Interruption of the visual cycle in a novel animal model induces progressive vision loss resembling Stargardts Disease

Sassone, F., Estay-Ahumada, C., Roux, M. J., Ciocca, D., Rossolillo, P., Birling, M.-C., Sparrow, J. R., Montenegro, D., & Hicks, D. (2024). Interruption of the visual cycle in a novel animal model induces progressive vision loss resembling Stargardts Disease. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-81869-y

Authors:

Fabiana Sassone

Catherine Estay-Ahumada

Michel Roux

Dominique Ciocca

Paola Rossolillo

Marie‐Christine Birling

Janet R. Sparrow

Diego Montenegro

David Hicks

Affiliated Authors:

Janet R. Sparrow

Diego Montenegro

Columbia Affiliation:

Vagelos College of Physicians and Surgeons
- Department of Ophthalmology
- Department of Pathology and Cell Biology

Subjects:

Disease Models, Animal (MeSH)

ATP-Binding Cassette Transporters (MeSH)

Stargardt Disease (MeSH)

Molecular Mechanisms of Retinal Degeneration and Regeneration (OpenAlex Topic)

Age-Related Macular Degeneration Research (OpenAlex Topic)

Optogenetics in Neuroscience and Biophysics Research (OpenAlex Topic)

Author Keywords:

stargardt's disease

retinal degeneration

animal model

gene editing

cone photoreceptors

electrophysiology

stargardt’s disease

Publication Type:

Article

Unique ID:

10.1038/s41598-024-81869-y

PMID:

DOI:

10.1038/s41598-024-81869-y

Journal:

Scientific Reports

Publication Date:

2024-12-28

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

View PubMed Record

View Scopus Record

View Web of Science Record

Record Created:

Wednesday, January 8, 2025 - 09:52