Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins

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Wu, W.-H., Tsai, Y.-T., Huang, I.-W., Cheng, C.-H., Hsu, C.-W., Cui, X., Ryu, J., Quinn, P. M. J., Caruso, S. M., Lin, C.-S., & Tsang, S. H. (2022). CRISPR genome surgery in a novel humanized model for autosomal dominant retinitis pigmentosa. Molecular Therapy, 30(4), 1407–1420. https://doi.org/10.1016/j.ymthe.2022.02.010
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Bao, K., Shan, C.-M., Chen, X., Raiymbek, G., Monroe, J. G., Fang, Y., Toda, T., Koutmou, K. S., Ragunathan, K., Lu, C., Berchowitz, L. E., & Jia, S. (2022). The cAMP signaling pathway regulates Epe1 protein levels and heterochromatin assembly. PLOS Genetics, 18(2), e1010049. https://doi.org/10.1371/journal.pgen.1010049
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Sen, A., Prager, B. C., Zhong, C., Park, D., Zhu, Z., Gimple, R. C., Wu, Q., Bernatchez, J. A., Beck, S., Clark, A. E., Siqueira-Neto, J. L., Rich, J. N., & McVicker, G. (2021). Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma. Cancer Research, 82(3), 377–390. https://doi.org/10.1158/0008-5472.can-21-0810
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Li, H., Engel, C., de la Hoya, M., Peterlongo, P., Yannoukakos, D., Livraghi, L., Radice, P., Thomassen, M., Hansen, T. V. O., Gerdes, A.-M., Nielsen, H. R., Caputo, S. M., Zambelli, A., Borg, A., Solano, A., Thomas, A., Parsons, M. T., Antoniou, A. C., Leslie, G., … Goldgar, D. E. (2022). Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants. Genetics in Medicine, 24(1), 119–129. https://doi.org/10.1016/j.gim.2021.08.016
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Martinez-Pastor, B., Silveira, G. G., Clarke, T. L., Chung, D., Gu, Y., Cosentino, C., Davidow, L. S., Mata, G., Hassanieh, S., Salsman, J., Ciccia, A., Bae, N., Bedford, M. T., Megias, D., Rubin, L. L., Efeyan, A., Dellaire, G., & Mostoslavsky, R. (2021). Assessing kinetics and recruitment of DNA repair factors using high content screens. Cell Reports, 37(13), 110176. https://doi.org/10.1016/j.celrep.2021.110176
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Barbuti, P. A., Ohnmacht, J., Santos, B. F. R., Antony, P. M., Massart, F., Cruciani, G., Dording, C. M., Pavelka, L., Casadei, N., Kwon, Y.-J., & Krüger, R. (2021). Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-01505-x
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Grancharova, T., Gerbin, K. A., Rosenberg, A. B., Roco, C. M., Arakaki, J. E., DeLizo, C. M., Dinh, S. Q., Donovan-Maiye, R. M., Hirano, M., Nelson, A. M., Tang, J., Theriot, J. A., Yan, C., Menon, V., Palecek, S. P., Seelig, G., & Gunawardane, R. N. (2021). A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-94732-1
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Dang, N., Lance-Byrne, A., Tung, A., Guo, X., Cecchi, R. J., Buchthal, J., Chavez, A., & Yeo, N. C. (2021). Generation and Application of a Versatile CRISPR Toolkit for Mammalian Cell Engineering. Synthetic Biology. https://doi.org/10.1093/synbio/ysab033
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Tisdale, J. F., Thompson, A. A., Mapara, M. Y., Kwiatkowski, J. L., Krishnamurti, L., Aygun, B., Kasow, K. A., Rifkin-Zenenberg, S., Schmidt, M., Pierciey, F. J., Whitney, D., Rogers, C., Nnamani, M., Foos, M., Miller, A., Zhang, X., Lynch, J., Walters, M. C., Kanter, J., & Bonner, M. (2021). Polyclonality Strongly Correlates with Biological Outcomes and Is Significantly Increased Following Improvements to the Phase 1/2 HGB-206 Protocol and Manufacturing of LentiGlobin for Sickle Cell Disease (SCD; bb1111) Gene Therapy (GT). Blood, 138(Supplement 1), 561–561. https://doi.org/10.1182/blood-2021-147760
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Taglialatela, A., Leuzzi, G., Sannino, V., Cuella-Martin, R., Huang, J.-W., Wu-Baer, F., Baer, R., Costanzo, V., & Ciccia, A. (2021). REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps. Molecular Cell, 81(19), 4008-4025.e7. https://doi.org/10.1016/j.molcel.2021.08.016
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Lebedeva, I. V., Wagner, M. V., Sahdeo, S., Lu, Y.-F., Anyanwu-Ofili, A., Harms, M. B., Wadia, J. S., Rajagopal, G., Boland, M. J., & Goldstein, D. B. (2021). Precision genetic cellular models identify therapies protective against ER stress. Cell Death & Disease, 12(8). https://doi.org/10.1038/s41419-021-04045-4
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