Regulation and Function of Microtubules in Cell Division

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Damuka, N., Gollepalli, K. K., Krizan, I., Bhoopal, B., Miller, M., Deep, O., Bashetti, N., Kumar, J. S., Orr, M. E., Macauley, S. L., Whitlow, C. T., Mintz, A., Lockhart, S. N., Craft, S., & Sai, K. K. S. (2024). Exploring Microtubule Dynamics in Alzheimer’s Disease: Longitudinal Assessment Using [11C]MPC‐6827 PET Imaging in APP/PS1 and PS301S Mouse Models. Alzheimer’s & Dementia, 20(S9). Portico. https://doi.org/10.1002/alz.093929
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Damuka, N., Miller, M., Krizan, I., Bhoopal, B., Orr, M. E., Gollepalli, K. K., Lockhart, S. N., Whitlow, C. T., Mintz, A., Craft, S., & Sai, K. K. S. (2024). PET Imaging of Microtubules in Cognitively Impaired and Normal Older Adults. Alzheimer’s & Dementia, 20(S8). Portico. https://doi.org/10.1002/alz.095392
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Bellutti, L., Macaisne, N., El Mossadeq, L., Ganeswaran, T., Canman, J. C., & Dumont, J. (2024). Regulation of outer kinetochore assembly during meiosis I and II by CENP-A and KNL-2/M18BP1 in C. elegans oocytes. Current Biology, 34(21), 4853-4868.e6. https://doi.org/10.1016/j.cub.2024.09.004
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Perrier, A., Guiglielmoni, N., Naquin, D., Gorrichon, K., Thermes, C., Lameiras, S., Dammermann, A., Schiffer, P. H., Brunstein, M., Canman, J. C., & Dumont, J. (2024). Maternal inheritance of functional centrioles in two parthenogenetic nematodes. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-50427-5
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Kumar, A., Larrea, D., Pero, M. E., Infante, P., Conenna, M., Shin, G. J., Van Elias, V., Grueber, W. B., Di Marcotullio, L., Area-Gomez, E., & Bartolini, F. (2024). MFN2 coordinates mitochondria motility with α-tubulin acetylation and this regulation is disrupted in CMT2A. IScience, 27(6), 109994. https://doi.org/10.1016/j.isci.2024.109994
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Infante, P., Conenna, M., Adabbo, G., Bufalieri, F., Bottero, M., Severini, L. L., Bartolini, F., & Marcotullio, L. D. (2024). MDB-28. THE CYTOSKELETON REGULATORS FORMINS CONTROL THE SHH PATHWAY AND ARE INVOLVED IN MEDULLOBLASTOMA TUMORIGENESIS. Neuro-Oncology, 26(Supplement_4), 0–0. https://doi.org/10.1093/neuonc/noae064.477
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Zhao, X., Quintremil, S., Rodriguez Castro, E. D., Cui, H., Moraga, D., Wang, T., Vallee, R. B., & Solmaz, S. R. (2024). Molecular mechanism for recognition of the cargo adapter Rab6GTPby the dynein adapter BicD2. Life Science Alliance, 7(7), e202302430. https://doi.org/10.26508/lsa.202302430
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Cheng, Y. L., Banu, M. A., Zhao, W., Rosenfeld, S. S., Canoll, P., & Sims, P. A. (2024). Multiplexed single-cell lineage tracing of mitotic kinesin inhibitor resistance in glioblastoma. Cell Reports, 43(5), 114139. https://doi.org/10.1016/j.celrep.2024.114139
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Galanti, L., Peritore, M., Gnügge, R., Cannavo, E., Heipke, J., Palumbieri, M. D., Steigenberger, B., Symington, L. S., Cejka, P., & Pfander, B. (2024). Dbf4-dependent kinase promotes cell cycle controlled resection of DNA double-strand breaks and repair by homologous recombination. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-46951-z
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Schneider, M., Potthoff, A., Karpel‐Massler, G., Schuss, P., Siegelin, M. D., Debatin, K., Duffau, H., Vatter, H., Herrlinger, U., & Westhoff, M. (2024). The Alcatraz‐Strategy: a roadmap to break the connectivity barrier in malignant brain tumours. Molecular Oncology. Portico. https://doi.org/10.1002/1878-0261.13642
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Pitayu-Nugroho, L., Aubry, M., Laband, K., Geoffroy, H., Ganeswaran, T., Primadhanty, A., Canman, J. C., & Dumont, J. (2023). Kinetochore component function in C. elegans oocytes revealed by 4D tracking of holocentric chromosomes. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-39702-z
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Parato, J., Peris, L., Qu, X., Goldberg, Y., Moutin, M.-J., Andrieux, A., & Bartolini, F. (2023). IMPAIRED α-TUBULIN RE-TYROSINATION LEADS TO SYNAPTIC DYSFUNCTION AND IS A FEATURE OF ALZHEIMER’S DISEASE. IBRO Neuroscience Reports, 15, S34. https://doi.org/10.1016/j.ibneur.2023.08.2116
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Ong, H. W., Liang, Y., Richardson, W., Lowry, E. R., Wells, C. I., Chen, X., Silvestre, M., Dempster, K., Silvaroli, J. A., Smith, J. L., Wichterle, H., Pabla, N. S., Ultanir, S. K., Bullock, A. N., Drewry, D. H., & Axtman, A. D. (2023). Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. ACS Chemical Neuroscience, 14(9), 1672–1685. https://doi.org/10.1021/acschemneuro.3c00135
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Banka, S., Bennington, A., Baker, M. J., Rijckmans, E., Clemente, G. D., Ansor, N. M., Sito, H., Prasad, P., Anyane-Yeboa, K., Badalato, L., Dimitrov, B., Fitzpatrick, D., Hurst, A. C. E., Jansen, A. C., Kelly, M. A., Krantz, I., Rieubland, C., Ross, M., Rudy, N. L., … Millard, T. H. (2022). Activating RAC1 variants in the switch II region cause a developmental syndrome and alter neuronal morphology. Brain, 145(12), 4232–4245. https://doi.org/10.1093/brain/awac049
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Lee, S. B., Garofano, L., Ko, A., D’Angelo, F., Frangaj, B., Sommer, D., Gan, Q., Kim, K., Cardozo, T., Iavarone, A., & Lasorella, A. (2022). Regulated interaction of ID2 with the anaphase-promoting complex links progression through mitosis with reactivation of cell-type-specific transcription. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29502-2
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Kim, S., Leong, A., Kim, M., & Yang, H. W. (2022). CDK4/6 initiates Rb inactivation and CDK2 activity coordinates cell-cycle commitment and G1/S transition. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-20769-5
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Damuka, N., Orr, M. E., Bansode, A. H., Krizan, I., Miller, M., Lee, J., Macauley, S. L., Whitlow, C. T., Mintz, A., Craft, S., & Solingapuram Sai, K. K. (2022). Preliminary mechanistic insights of a brain-penetrant microtubule imaging PET ligand in a tau-knockout mouse model. EJNMMI Research, 12(1). https://doi.org/10.1186/s13550-022-00912-z
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Peris, L., Parato, J., Qu, X., Soleilhac, J. M., Lanté, F., Kumar, A., Pero, M. E., Martínez-Hernández, J., Corrao, C., Falivelli, G., Payet, F., Gory-Fauré, S., Bosc, C., Blanca Ramirez, M., Sproul, A., Brocard, J., Di Cara, B., Delagrange, P., Buisson, A., … Andrieux, A. (2022). Tubulin tyrosination regulates synaptic function and is disrupted in Alzheimer’s disease. Brain, 145(7), 2486–2506. https://doi.org/10.1093/brain/awab436
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Gavade, J. N., Puccia, C. M., Herod, S. G., Trinidad, J. C., Berchowitz, L. E., & Lacefield, S. (2022). Identification of 14-3-3 proteins, Polo kinase, and RNA-binding protein Pes4 as key regulators of meiotic commitment in budding yeast. Current Biology, 32(7), 1534-1547.e9. https://doi.org/10.1016/j.cub.2022.02.022
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Wang, F., Liu, Y., Qiu, W., Shum, E., Feng, M., Zhao, D., Zheng, D., Borczuk, A., Cheng, H., & Halmos, B. (2022). Functional Analysis of MET Exon 14 Skipping Alteration in Cancer Invasion and Metastatic Dissemination. Cancer Research, 82(7), 1365–1379. https://doi.org/10.1158/0008-5472.can-21-1327
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Lu, H., Gomaa, A., Wang-Bishop, L., Ballout, F., Hu, T., McDonald, O., Washington, M. K., Livingstone, A. S., Wang, T. C., Peng, D., El-Rifai, W., & Chen, Z. (2022). Unfolded Protein Response Is Activated by Aurora Kinase A in Esophageal Adenocarcinoma. Cancers, 14(6), 1401. https://doi.org/10.3390/cancers14061401
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Hirsch, S. M., Edwards, F., Shirasu-Hiza, M., Dumont, J., & Canman, J. C. (2022). Functional midbody assembly in the absence of a central spindle. Journal of Cell Biology, 221(3). https://doi.org/10.1083/jcb.202011085
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Damuka, N., Macauley, S. L., Orr, M. E., Shively, C. A., Lockhart, S. N., Bansode, A., Frye, B. M., Mintz, A., Kim, J., Register, T. C., Whitlow, C. T., Craft, S., & Solingapuram Sai, K. K. (2021). Initial biological evaluation of a novel microtubule‐based PET ligand in rodent and NHP models of AD. Alzheimer’s & Dementia, 17(S4). Portico. https://doi.org/10.1002/alz.052101
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