Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer

Wasko, U. N., Jiang, J., Dalton, T. C., Curiel-Garcia, A., Edwards, A. C., Wang, Y., Lee, B., Orlen, M., Tian, S., Stalnecker, C. A., Drizyte-Miller, K., Menard, M., Dilly, J., Sastra, S. A., Palermo, C. F., Hasselluhn, M. C., Decker-Farrell, A. R., Chang, S., Jiang, L., … Olive, K. P. (2024). Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature, 629(8013), 927–936. https://doi.org/10.1038/s41586-024-07379-z
Authors:
Urszula N. Wasko
Jingjing Jiang
Tanner C. Dalton
Álvaro Curiel‐García
A. Cole Edwards
Yingyun Wang
Bianca J. Lee
Margo Orlen
Sha Tian
Clint A. Stalnecker
Kristina Drizyte‐Miller
Marie Ménard
Julien Dilly
Stephen A. Sastra
Carmine F. Palermo
Marie C. Hasselluhn
Amanda R. Decker-Farrell
Stephanie Chang
Lingyan Jiang
Wei Xing
Yu Chi Yang
Ciara Helland
Haley Courtney
Yevgeniy Gindin
Karl Muonio
Ruiping Zhao
Samantha B. Kemp
Cynthia Clendenin
Rina Sor
William P. Vostrejs
Priya S. Hibshman
Amber M. Amparo
Connor J. Hennessey
Matthew G. Rees
Melissa M. Ronan
Jennifer A. Roth
Jens Brodbeck
Lorenzo Tomassoni
Basil Bakir
Nicholas D. Socci
Laura E. Herring
Natalie K. Barker
Junning Wang
James M. Cleary
Brian M. Wolpin
John A. Chabot
Michael D. Kluger
Gulam A. Manji
Kenneth Y. Tsai
Miroslav Sekulic
Stephen M. Lagana
Andrea Califano
Elsa Quintana
Zhengping Wang
Jacqueline A.M. Smith
Matthew Holderfield
David Wildes
Scott W. Lowe
Michael A. Badgley
Andrew J. Aguirre
Robert H. Vonderheide
Ben Z. Stanger
Timour Baslan
Channing J. Der
Mallika Singh
Kenneth P. Olive
Affiliated Authors:
Urszula N. Wasko
Tanner C. Dalton
Álvaro Curiel‐García
Stephen A. Sastra
Carmine F. Palermo
Marie C. Hasselluhn
Amanda R. Decker-Farrell
Lorenzo Tomassoni
Basil Bakir
John A. Chabot
Michael D. Kluger
Gulam A. Manji
Miroslav Sekulic
Stephen M. Lagana
Andrea Califano
Michael A. Badgley
Kenneth P. Olive
Columbia Affiliation:
Subjects:
Antineoplastic Agents (MeSH)
Carcinoma, Pancreatic Ductal (MeSH)
Guanosine Triphosphate (MeSH)
Pancreatic Neoplasms (MeSH)
Proto-Oncogene Proteins p21(ras) (MeSH)
Pancreatic Cancer Research and Treatment (OpenAlex Topic)
Role of Pim Oncogenes in Tumorigenesis (OpenAlex Topic)
Molecular Mechanisms of Ras Signaling Pathways (OpenAlex Topic)
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Publication Type:
Article
Unique ID:
10.1038/s41586-024-07379-z
PMID:
38588697
DOI:
10.1038/s41586-024-07379-z
Journal:
Nature
Publication Date:
Data Source:
OpenAlex
Source Link:
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