Molecular Mechanisms of Ras Signaling Pathways

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Fontana, M., Maurer, M. S., Gillmore, J. D., Bender, S., Jay, P. Y., & Solomon, S. D. (2025). Worsening of Heart Failure in Outpatients With Transthyretin Amyloidosis and Cardiomyopathy in the APOLLO-B Trial. Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2024.10.097
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Wasko, U. N., Jiang, J., Dalton, T. C., Curiel-Garcia, A., Edwards, A. C., Wang, Y., Lee, B., Orlen, M., Tian, S., Stalnecker, C. A., Drizyte-Miller, K., Menard, M., Dilly, J., Sastra, S. A., Palermo, C. F., Hasselluhn, M. C., Decker-Farrell, A. R., Chang, S., Jiang, L., … Olive, K. P. (2024). Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature, 629(8013), 927–936. https://doi.org/10.1038/s41586-024-07379-z
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Garcia‐Pavia, P., Grogan, M., Kale, P., Berk, J. L., Maurer, M. S., Conceição, I., Di Carli, M., Solomon, S. D., Chen, C., Yureneva, E., Vest, J., & Gillmore, J. D. (2024). Impact of vutrisiran on exploratory cardiac parameters in hereditary transthyretin‐mediated amyloidosis with polyneuropathy. European Journal of Heart Failure, 26(2), 397–410. Portico. https://doi.org/10.1002/ejhf.3138
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Postler, T. S., Wang, A., Brundu, F. G., Wang, P., Wu, Z., Butler, K. E., Grinberg-Bleyer, Y., Krishnareddy, S., Lagana, S. M., Saqi, A., Oeckinghaus, A., Rabadan, R., & Ghosh, S. (2023). A pan-cancer analysis implicates human NKIRAS1 as a tumor-suppressor gene. Proceedings of the National Academy of Sciences, 120(46). https://doi.org/10.1073/pnas.2312595120
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Thummalapalli, R., Bernstein, E., Herzberg, B., Li, B. T., Iqbal, A., Preeshagul, I., Santini, F. C., Eng, J., Ladanyi, M., Yang, S.-R., Shen, R., Lito, P., Riely, G. J., Sabari, J. K., & Arbour, K. C. (2023). Clinical and Genomic Features of Response and Toxicity to Sotorasib in a Real-World Cohort of Patients With Advanced KRAS G12C-Mutant Non–Small Cell Lung Cancer. JCO Precision Oncology, 7. https://doi.org/10.1200/po.23.00030
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Johnson, J. L., Yaron, T. M., Huntsman, E. M., Kerelsky, A., Song, J., Regev, A., Lin, T.-Y., Liberatore, K., Cizin, D. M., Cohen, B. M., Vasan, N., Ma, Y., Krismer, K., Robles, J. T., van de Kooij, B., van Vlimmeren, A. E., Andrée-Busch, N., Käufer, N. F., Dorovkov, M. V., … Cantley, L. C. (2023). An atlas of substrate specificities for the human serine/threonine kinome. Nature, 613(7945), 759–766. https://doi.org/10.1038/s41586-022-05575-3
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Banka, S., Bennington, A., Baker, M. J., Rijckmans, E., Clemente, G. D., Ansor, N. M., Sito, H., Prasad, P., Anyane-Yeboa, K., Badalato, L., Dimitrov, B., Fitzpatrick, D., Hurst, A. C. E., Jansen, A. C., Kelly, M. A., Krantz, I., Rieubland, C., Ross, M., Rudy, N. L., … Millard, T. H. (2022). Activating RAC1 variants in the switch II region cause a developmental syndrome and alter neuronal morphology. Brain, 145(12), 4232–4245. https://doi.org/10.1093/brain/awac049
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Wang, Y., Spolitu, S., Zadroga, J. A., Sarecha, A. K., & Ozcan, L. (2022). Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia. Cell Reports, 40(8), 111259. https://doi.org/10.1016/j.celrep.2022.111259
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Zhang, X., Wang, B. Z., Kim, M., Nash, T. R., Liu, B., Rao, J., Lock, R., Tamargo, M., Soni, R. K., Belov, J., Li, E., Vunjak-Novakovic, G., & Fine, B. (2022). STK25 inhibits PKA signaling by phosphorylating PRKAR1A. Cell Reports, 40(7), 111203. https://doi.org/10.1016/j.celrep.2022.111203
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Cuddy, S. A. M., Jerosch-Herold, M., Falk, R. H., Kijewski, M. F., Singh, V., Ruberg, F. L., Sanchorawala, V., Landau, H., Maurer, M. S., Yee, A. J., Bianchi, G., Di Carli, M. F., Liao, R., Kwong, R. Y., & Dorbala, S. (2022). Myocardial Composition in Light-Chain Cardiac Amyloidosis More Than 1 Year After Successful Therapy. JACC: Cardiovascular Imaging, 15(4), 594–603. https://doi.org/10.1016/j.jcmg.2021.09.032
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