npj Parkinson's Disease
Displaying 1 - 22 of 22
Merino-Galán, L., Zamarbide, M., Belloso-Iguerategui, A., Alonso-Moreno, M. C., Gago, B., Reinares-Sebastián, A., Blesa, J., Dumitriu, D., Quiroga-Varela, A., & Rodríguez-Oroz, M. C. (2025). Resilience of striatal synaptic plasticity over early structural adaptations in premotor parkinsonism. Npj Parkinson’s Disease, 11(1). https://doi.org/10.1038/s41531-025-00994-1
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Columbia Affiliation
Johansson, E., Freuchet, A., Williams, G. P., Michealis, T., Frazier, A., Litvan, I., Goldman, J. G., Alcalay, R. N., Standaert, D. G., Amara, A. W., Stover, N., Fon, E. A., Postuma, R. B., Sidney, J., Sulzer, D., Lindestam Arlehamn, C. S., & Sette, A. (2025). T cell responses towards PINK1 and α-synuclein are elevated in prodromal Parkinson’s disease. Npj Parkinson’s Disease, 11(1). https://doi.org/10.1038/s41531-025-01001-3
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Columbia Affiliation
Freuchet, A., Johansson, E., Frazier, A., Litvan, I., Goldman, J. G., Alcalay, R. N., Sulzer, D., Lindestam Arlehamn, C. S., & Sette, A. (2025). Differential memory enrichment of cytotoxic CD4 T cells in Parkinson’s disease patients reactive to α-synuclein. Npj Parkinson’s Disease, 11(1). https://doi.org/10.1038/s41531-025-00981-6
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Columbia Affiliation
Parlar, S. C., Senkevich, K., Yu, E., Ruskey, J. A., Ahmad, J., Asayesh, F., Spiegelman, D., Waters, C., Monchi, O., Dauvilliers, Y., Dupré, N., Greenbaum, L., Hassin-Baer, S., Miliukhina, I., Timofeeva, A., Emelyanov, A., Pchelina, S., Alcalay, R. N., Fon, E. A., … Gan-Or, Z. (2025). LRRK2 rare-variant per-domain genetic burden in Parkinson’s Disease: association confined to the kinase domain. Npj Parkinson’s Disease, 11(1). https://doi.org/10.1038/s41531-025-00934-z
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Columbia Affiliation
Barbuti, P. A., Guardia-Laguarta, C., Yun, T., Chatila, Z. K., Flowers, X., Wong, C., Santos, B. F. R., Larsen, S. B., Lotti, J. S., Hattori, N., Bradshaw, E., Dettmer, U., Fanning, S., Menon, V., Reddy, H., Teich, A. F., Krüger, R., Area-Gomez, E., & Przedborski, S. (2025). The role of alpha-synuclein in synucleinopathy: Impact on lipid regulation at mitochondria–ER membranes. Npj Parkinson’s Disease, 11(1). https://doi.org/10.1038/s41531-025-00960-x
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Columbia Affiliation
Vagelos College of Physicians and Surgeons; Department of Neurology; Motor Neuron Center; Taub Institute for Research on Alzheimer’s Disease and the Aging Brain; Center for Translational and Computational Neuroimmunology; Department of Pathology and Cell Biology; Department of Neuroscience; Carol and Gene Ludwig Center for Research on Neurodegeneration
Ren, W.-H., Chen, B., He, J.-Q., Qi, Y.-M., Yan, Y.-Y., Jin, S.-X., & Chang, Y. (2025). Patterns of cerebellar cortex hypermetabolism on motor and cognitive functions in PD. Npj Parkinson’s Disease, 11(1). https://doi.org/10.1038/s41531-025-00931-2
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Columbia Affiliation
Dam, T., Pagano, G., Brumm, M. C., Gochanour, C., Poston, K. L., Weintraub, D., Chahine, L. M., Coffey, C., Tanner, C. M., Kopil, C. M., Xiao, Y., Chowdhury, S., Concha-Marambio, L., DiBiaso, P., Foroud, T., Frasier, M., Jennings, D., Kieburtz, K., Merchant, K., … Wubuli, D. (2024). Neuronal alpha-Synuclein Disease integrated staging system performance in PPMI, PASADENA, and SPARK baseline cohorts. Npj Parkinson’s Disease, 10(1). https://doi.org/10.1038/s41531-024-00789-w
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Oas, H., Cook, L., Schwantes-An, T.-H., Walsh, L. E., Wills, A.-M., Mata, I. F., Nance, M. A., Beck, J. C., Naito, A., Marder, K., Alcalay, R. N., & Verbrugge, J. (2024). Participant-reported personal utility of genetic testing for Parkinson’s disease and interest in clinical trial participation. Npj Parkinson’s Disease, 10(1). https://doi.org/10.1038/s41531-024-00805-z
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Columbia Affiliation
Senkevich, K., Parlar, S. C., Chantereault, C., Yu, E., Ahmad, J., Ruskey, J. A., Asayesh, F., Spiegelman, D., Waters, C., Monchi, O., Dauvilliers, Y., Dupré, N., Miliukhina, I., Timofeeva, A., Emelyanov, A., Pchelina, S., Greenbaum, L., Hassin-Baer, S., Alcalay, R. N., & Gan-Or, Z. (2024). Are rare heterozygous SYNJ1 variants associated with Parkinson’s disease? Npj Parkinson’s Disease, 10(1). https://doi.org/10.1038/s41531-024-00809-9
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Columbia Affiliation
Wang, V. A., Delaney, S., Flynn, L. E., Racette, B. A., Miller, G. W., Braun, D., Zanobetti, A., & Mork, D. (2024). The effect of air pollution on hospitalizations with Parkinson’s disease among medicare beneficiaries nationwide. Npj Parkinson’s Disease, 10(1). https://doi.org/10.1038/s41531-024-00815-x
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Columbia Affiliation
Gala, A. S., Wilkins, K. B., Petrucci, M. N., Kehnemouyi, Y. M., Velisar, A., Trager, M. H., & Bronte-Stewart, H. M. (2024). The digital signature of emergent tremor in Parkinson’s disease. Npj Parkinson’s Disease, 10(1). https://doi.org/10.1038/s41531-024-00754-7
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Columbia Affiliation
Weber, S., Menees, K. B., Park, J., Agin-Liebes, J., Lin, C.-C., Alcalay, R. N., & Lee, J.-K. (2024). Distinctive CD56dim NK subset profiles and increased NKG2D expression in blood NK cells of Parkinson’s disease patients. Npj Parkinson’s Disease, 10(1). https://doi.org/10.1038/s41531-024-00652-y
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Columbia Affiliation
Ramalingam, N., Jin, S.-X., Moors, T. E., Fonseca-Ornelas, L., Shimanaka, K., Lei, S., Cam, H. P., Watson, A. H., Brontesi, L., Ding, L., Hacibaloglu, D. Y., Jiang, H., Choi, S. J., Kanter, E., Liu, L., Bartels, T., Nuber, S., Sulzer, D., Mosharov, E. V., … Dettmer, U. (2023). Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity. Npj Parkinson’s Disease, 9(1). https://doi.org/10.1038/s41531-023-00444-w
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Columbia Affiliation
Avisar, H., Guardia-Laguarta, C., Surface, M., Papagiannakis, N., Maniati, M., Antonellou, R., Papadimitriou, D., Koros, C., Athanassiadou, A., Przedborski, S., Lerner, B., Stefanis, L., Area-Gomez, E., & Alcalay, R. N. (2022). Lipid level alteration in human and cellular models of alpha synuclein mutations. Npj Parkinson’s Disease, 8(1). https://doi.org/10.1038/s41531-022-00313-y
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Columbia Affiliation
Kedariti, M., Frattini, E., Baden, P., Cogo, S., Civiero, L., Ziviani, E., Zilio, G., Bertoli, F., Aureli, M., Kaganovich, A., Cookson, M. R., Stefanis, L., Surface, M., Deleidi, M., Di Fonzo, A., Alcalay, R. N., Rideout, H., Greggio, E., & Plotegher, N. (2022). LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson’s disease. Npj Parkinson’s Disease, 8(1). https://doi.org/10.1038/s41531-022-00354-3
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Columbia Affiliation
Dhanwani, R., Lima-Junior, J. R., Sethi, A., Pham, J., Williams, G., Frazier, A., Xu, Y., Amara, A. W., Standaert, D. G., Goldman, J. G., Litvan, I., Alcalay, R. N., Peters, B., Sulzer, D., Arlehamn, C. S. L., & Sette, A. (2022). Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signatures. Npj Parkinson’s Disease, 8(1). https://doi.org/10.1038/s41531-022-00282-2
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Columbia Affiliation
Cook, L., Schulze, J., Uhlmann, W. R., Verbrugge, J., Marder, K., Lee, A. J., Wang, Y., Alcalay, R. N., Nance, M., & Beck, J. C. (2022). Tools for communicating risk for Parkinson’s disease. Npj Parkinson’s Disease, 8(1). https://doi.org/10.1038/s41531-022-00432-6
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Columbia Affiliation
Simuni, T., Merchant, K., Brumm, M. C., Cho, H., Caspell-Garcia, C., Coffey, C. S., Chahine, L. M., Alcalay, R. N., Nudelman, K., Foroud, T., Mollenhauer, B., Siderowf, A., Tanner, C., Iwaki, H., Sherer, T., Marek, K., Siderowf, A., … Tauscher, J. (2022). Longitudinal clinical and biomarker characteristics of non-manifesting LRRK2 G2019S carriers in the PPMI cohort. Npj Parkinson’s Disease, 8(1). https://doi.org/10.1038/s41531-022-00404-w
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Columbia Affiliation
Petropoulou-Vathi, L., Simitsi, A., Valkimadi, P.-E., Kedariti, M., Dimitrakopoulos, L., Koros, C., Papadimitriou, D., Papadimitriou, A., Stefanis, L., Alcalay, R. N., & Rideout, H. J. (2022). Distinct profiles of LRRK2 activation and Rab GTPase phosphorylation in clinical samples from different PD cohorts. Npj Parkinson’s Disease, 8(1). https://doi.org/10.1038/s41531-022-00336-5
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Columbia Affiliation
Chalazonitis, A., Rao, M., & Sulzer, D. (2022). Similarities and differences between nigral and enteric dopaminergic neurons unravel distinctive involvement in Parkinson’s disease. Npj Parkinson’s Disease, 8(1). https://doi.org/10.1038/s41531-022-00308-9
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Columbia Affiliation
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Liu, B., Sjölander, A., Pedersen, N. L., Ludvigsson, J. F., Chen, H., Fang, F., & Wirdefeldt, K. (2021). Irritable bowel syndrome and Parkinson’s disease risk: register-based studies. Npj Parkinson’s Disease, 7(1). https://doi.org/10.1038/s41531-020-00145-8
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Columbia Affiliation
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Feeney, M. P., Xu, Y., Surface, M., Shah, H., Vanegas-Arroyave, N., Chan, A. K., Delaney, E., Przedborski, S., Beck, J. C., & Alcalay, R. N. (2021). The impact of COVID-19 and social distancing on people with Parkinson’s disease: a survey study. Npj Parkinson’s Disease, 7(1). https://doi.org/10.1038/s41531-020-00153-8
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Columbia Affiliation
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