R01AG026390

NIH – National Institute On Aging

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Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways

Bradley, J., Pottier, C., da Fonseca, E. L., Kurup, J. T., Western, D., Wang, C., Neupane, A., Ray, N. R., Jean‐Francois, M., Ali, M., Timsina, J., Bergmann, K., Budde, J., Martin, E. R., Pericak‐Vance, M. A., Cuccaro, M., Naj, A. C., Kunkle, B. W., … Cruchaga, C. (2025). Novel early‐onset Alzheimer‐associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways. Alzheimer’s & Dementia, 21(6). Portico. https://doi.org/10.1002/alz.70377
Authors:
Joseph Bradley
Cyril Pottier
Daniel Western
Ciyang Wang
Achal Neupane
Muhammad Ali
Jigyasha Timsina
Kristy Bergmann
John Budde
Victoria Fernandez
Carlos Cruchaga
Eder Lucio da Fonseca
Melissa Jean-Francois
Eden R. Martin
Margaret A. Pericak-Vance
Michael Cuccaro
Brian W. Kunkle
Gary W. Beecham
Jiji Thulaseedhara Kurup
Nicholas R. Ray
Christiane Reitz
Adam C. Naj
Gerard D. Schellenberg
Jonathan Haines
John C. Morris
David M. Holtzman
Richard J. Perrin
Affiliated Authors:
Jiji Thulaseedhara Kurup
Nicholas R. Ray
Christiane Reitz
Columbia Affiliation:
Author Keywords:
adgc
alzheimer's disease risk
early onset alzheimer's disease
gene-mapping
genetic ancestry
gwas
late onset alzheimer's disease
meta-analysis
multi-ancestry
glutamic acid
aged
alzheimer disease
female
genetic predisposition
genetics
genome-wide association study
human
immunology
male
metabolism
middle aged
onset age
quantitative trait locus
signal transduction
single nucleotide polymorphism
age of onset
genetic predisposition to disease
humans
polymorphism, single nucleotide
quantitative trait loci
gene‐mapping
meta‐analysis
multi‐ancestry
Grants:
KL2RR024151 (NIH – National Center for Research Resources)
P01AG002219 (NIH – National Institute On Aging)
P01AG003949 (NIH – National Institute On Aging)
P01AG003991 (NIH – National Institute On Aging)
P01AG009464 (NIH – National Institute on Aging)
P01AG010491 (NIH – National Institute On Aging)
P01AG017216 (NIH – National Institute On Aging)
P01AG019724 (NIH – National Institute On Aging)
P01AG026276 (NIH – National Institute On Aging)
P20MD000546 (NIH – National Institute On Minority Health and Health Disparities)
P30AG008017 (NIH – National Institute On Aging)
P30AG008051 (NIH – National Institute On Aging)
P30AG010124 (NIH – National Institute On Aging)
P30AG010129 (NIH – National Institute On Aging)
P30AG010133 (NIH – National Institute On Aging)
P30AG010161 (NIH – National Institute On Aging)
P30AG012300 (NIH – National Institute On Aging)
P30AG013846 (NIH – National Institute On Aging)
P30AG013854 (NIH – National Institute On Aging)
P30AG019610 (NIH – National Institute On Aging)
P30AG028377 (NIH – National Institute On Aging)
P30AG028383 (NIH – National Institute On Aging)
P30AG066444 (NIH – National Institute On Aging)
P30AG066515 (NIH – National Institute On Aging)
P30AG072975 (NIH – National Institute On Aging)
P50AG005128 (NIH – National Institute on Aging)
P50AG005131 (NIH – National Institute On Aging)
P50AG005133 (NIH – National Institute On Aging)
P50AG005134 (NIH – National Institute On Aging)
P50AG005136 (NIH – National Institute On Aging)
P50AG005138 (NIH – National Institute On Aging)
P50AG005142 (NIH – National Institute On Aging)
P50AG005144 (NIH – National Institute on Aging)
P50AG005146 (NIH – National Institute On Aging)
P50AG005681 (NIH – National Institute On Aging)
P50AG008671 (NIH – National Institute On Aging)
P50AG008702 (NIH – National Institute On Aging)
P50AG016570 (NIH – National Institute On Aging)
P50AG016573 (NIH – National Institute On Aging)
P50AG016574 (NIH – National Institute On Aging)
P50AG016582 (NIH – National Institute On Aging)
P50AG023501 (NIH – National Institute On Aging)
P50AG025688 (NIH – National Institute On Aging)
P50AG025711 (NIH – National Institute On Aging)
P50AG033514 (NIH – National Institute On Aging)
P50MH060451 (NIH – National Institute of Mental Health)
P50NS039764 (NIH – National Institute of Neurological Disorders and Stroke)
R00AG062723 (NIH – National Institute on Aging)
R01AG009029 (NIH – National Institute on Aging)
R01AG009956 (NIH – National Institute On Aging)
R01AG012101 (NIH – National Institute On Aging)
R01AG013616 (NIH – National Institute On Aging)
R01AG015819 (NIH – National Institute On Aging)
R01AG017173 (NIH – National Institute On Aging)
R01AG017917 (NIH – National Institute On Aging)
R01AG018023 (NIH – National Institute On Aging)
R01AG019085 (NIH – National Institute On Aging)
R01AG019757 (NIH – National Institute on Aging)
R01AG020688 (NIH – National Institute on Aging)
R01AG021547 (NIH – National Institute on Aging)
R01AG022018 (NIH – National Institute On Aging)
R01AG022374 (NIH – National Institute On Aging)
R01AG025259 (NIH – National Institute On Aging)
R01AG026390 (NIH – National Institute On Aging)
R01AG026916 (NIH – National Institute on Aging)
R01AG027944 (NIH – National Institute On Aging)
R01AG028786 (NIH – National Institute On Aging)
R01AG030146 (NIH – National Institute On Aging)
R01AG030653 (NIH – National Institute On Aging)
R01AG031581 (NIH – National Institute On Aging)
R01AG032990 (NIH – National Institute On Aging)
R01AG033193 (NIH – National Institute On Aging)
R01AG035137 (NIH – National Institute On Aging)
R01AG036836 (NIH – National Institute On Aging)
R01AG037212 (NIH – National Institute On Aging)
R01AG041232 (NIH – National Institute On Aging)
R01AG041718 (NIH – National Institute On Aging)
R01AG041797 (NIH – National Institute On Aging)
R01AG042437 (NIH – National Institute On Aging)
R01AG044546 (NIH – National Institute On Aging)
R01AG048927 (NIH – National Institute On Aging)
R01AG058501 (NIH – National Institute on Aging)
R01AG074007 (NIH – National Institute on Aging)
R01CA129769 (NIH – National Cancer Institute)
R01MH080295 (NIH – National Institute of Mental Health)
R01NS059873 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS080820 (NIH – National Institute of Neurological Disorders and Stroke)
R37AG015473 (NIH – National Institute On Aging)
RC2AG036502 (NIH – National Institute On Aging)
RC2AG036528 (NIH – National Institute On Aging)
RC2AG036650 (NIH – National Institute On Aging)
RF1AG015473 (NIH – National Institute On Aging)
RF1AG015819 (NIH – National Institute On Aging)
RF1AG022018 (NIH – National Institute On Aging)
RF1AG044546 (NIH – National Institute On Aging)
RF1AG053303 (NIH – National Institute On Aging)
RF1AG057440 (NIH – National Institute On Aging)
RF1AG058501 (NIH – National Institute On Aging)
RF1AG074007 (NIH – National Institute On Aging)
U01AG006781 (NIH – National Institute On Aging)
U01AG006786 (NIH – National Institute On Aging)
U01AG010483 (NIH – National Institute On Aging)
U01AG017173 (NIH – National Institute on Aging)
U01AG024904 (NIH – National Institute On Aging)
U01AG032984 (NIH – National Institute On Aging)
U01AG046139 (NIH – National Institute On Aging)
U01AG046152 (NIH – National Institute On Aging)
U01AG046170 (NIH – National Institute On Aging)
U01AG052410 (NIH – National Institute On Aging)
U01AG058922 (NIH – National Institute On Aging)
U01AG061356 (NIH – National Institute On Aging)
U01HG004610 (NIH – National Human Genome Research Institute)
U01HG006375 (NIH – National Human Genome Research Institute)
U01HG008657 (NIH – National Human Genome Research Institute)
U24AG021886 (NIH – National Institute On Aging)
U24AG026395 (NIH – National Institute On Aging)
U24AG041689 (NIH – National Institute On Aging)
U24AG061340 (NIH – National Institute on Aging)
U24AG072122 (NIH – National Institute On Aging)
U24NS072026 (NIH – National Institute of Neurological Disorders and Stroke)
U54AG052427 (NIH – National Institute On Aging)
UL1RR029893 (NIH – National Center for Research Resources)
Publication Type:
Article
Unique ID:
10.1002/alz.70377
PMID:
40556318
DOI:
10.1002/alz.70377
Journal:
Alzheimer's and Dementia
Publication Date:
Data Source:
Web of Science
Source Link:
View Web of Science Record
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View Scopus Record
View PubMed Record

Record Created:

Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry

Ray, N. R., Kunkle, B. W., Hamilton‐Nelson, K., Kurup, J. T., Rajabli, F., Qiao, M., Vardarajan, B. N., Cosacak, M. I., Kizil, C., Jean‐Francois, M., Cuccaro, M., Reyes‐Dumeyer, D., Cantwell, L., Kuzma, A., Vance, J. M., Gao, S., Hendrie, H. C., Baiyewu, O., … Ogunniyi, A. (2024). Extended genome‐wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer’s disease in individuals of African ancestry. Alzheimer’s & Dementia. Portico. https://doi.org/10.1002/alz.13880
Authors:
Nicholas R Ray
Brian W Kunkle
Kara Hamilton-Nelson
Jiji T Kurup
Farid Rajabli
Min Qiao
Badri N Vardarajan
Mehmet I Cosacak
Caghan Kizil
Melissa Jean-Francois
Michael Cuccaro
Dolly Reyes-Dumeyer
Laura Cantwell
Amanda Kuzma
Jeffery M Vance
Sujuan Gao
Hugh C Hendrie
Olusegun Baiyewu
Adesola Ogunniyi
Rufus O Akinyemi
Wan-Ping Lee
Eden R Martin
Li-San Wang
Gary W Beecham
William S Bush
Wanying Xu
Fulai Jin
Liyong Wang
Lindsay A Farrer
Jonathan L Haines
Goldie S Byrd
Gerard D Schellenberg
Richard Mayeux
Margaret A Pericak-Vance
Christiane Reitz
Affiliated Authors:
Nicholas R Ray
Jiji T Kurup
Min Qiao
Badri N Vardarajan
Caghan Kizil
Dolly Reyes-Dumeyer
Richard Mayeux
Christiane Reitz
Columbia Affiliation:
Author Keywords:
african americans
african genome panel
alzheimer's disease
genome-wide association study
genome‐wide association study
Grants:
R01CA129769 (NIH – National Cancer Institute)
R01CA267872 (NIH – National Cancer Institute)
UL1RR029893 (NIH – National Center for Research Resources)
KL2RR024151 (NIH – National Center for Research Resources)
R01HG009658 (NIH – National Human Genome Research Institute)
U01HG008657 (NIH – National Human Genome Research Institute)
U01HG006375 (NIH – National Human Genome Research Institute)
R01HG012384 (NIH – National Human Genome Research Institute)
U01HG004610 (NIH – National Human Genome Research Institute)
R01DK131437 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01MH080295 (NIH – National Institute of Mental Health)
P50MH060451 (NIH – National Institute of Mental Health)
UG3NS132061 (NIH – National Institute of Neurological Disorders and Stroke)
R01NS059873 (NIH – National Institute of Neurological Disorders and Stroke)
P50NS039764 (NIH – National Institute of Neurological Disorders and Stroke)
R01AG012101 (NIH – National Institute On Aging)
U01AG062943 (NIH – National Institute On Aging)
R37AG015473 (NIH – National Institute On Aging)
U01AG052410 (NIH – National Institute On Aging)
P30AG013854 (NIH – National Institute On Aging)
R01AG072547 (NIH – National Institute On Aging)
P50AG008702 (NIH – National Institute On Aging)
R01AG022018 (NIH – National Institute On Aging)
P30AG008017 (NIH – National Institute On Aging)
R01AG041797 (NIH – National Institute On Aging)
U01AG072579 (NIH – National Institute On Aging)
P30AG013846 (NIH – National Institute On Aging)
R01AG022374 (NIH – National Institute On Aging)
R01AG032990 (NIH – National Institute On Aging)
P30AG019610 (NIH – National Institute On Aging)
P50AG005131 (NIH – National Institute On Aging)
R01AG033193 (NIH – National Institute On Aging)
R01AG030653 (NIH – National Institute On Aging)
R01AG027944 (NIH – National Institute On Aging)
U19AG074865 (NIH – National Institute On Aging)
R01AG048927 (NIH – National Institute On Aging)
U01AG061356 (NIH – National Institute On Aging)
R01AG026390 (NIH – National Institute On Aging)
R01AG041718 (NIH – National Institute On Aging)
P30AG066462 (NIH – National Institute On Aging)
R01AG031581 (NIH – National Institute On Aging)
U01AG010483 (NIH – National Institute On Aging)
P50AG025688 (NIH – National Institute On Aging)
P50AG005133 (NIH – National Institute On Aging)
U01AG024904 (NIH – National Institute On Aging)
P30AG028383 (NIH – National Institute On Aging)
U01AG057659 (NIH – National Institute On Aging)
U01AG016976 (NIH – National Institute On Aging)
P50AG005681 (NIH – National Institute On Aging)
U01AG046161 (NIH – National Institute On Aging)
P30AG008051 (NIH – National Institute On Aging)
P50AG005142 (NIH – National Institute On Aging)
P01AG026276 (NIH – National Institute On Aging)
R01AG035137 (NIH – National Institute On Aging)
RF1AG059018 (NIH – National Institute On Aging)
P50AG016570 (NIH – National Institute On Aging)
R01AG036836 (NIH – National Institute On Aging)
P50AG016573 (NIH – National Institute On Aging)
R01AG019085 (NIH – National Institute On Aging)
P30AG012300 (NIH – National Institute On Aging)
R01AG042437 (NIH – National Institute On Aging)
P50AG023501 (NIH – National Institute On Aging)
P30AG010124 (NIH – National Institute On Aging)
P30AG066518 (NIH – National Institute On Aging)
R01AG037212 (NIH – National Institute On Aging)
R01AG013616 (NIH – National Institute On Aging)
RF1AG057473 (NIH – National Institute On Aging)
P30AG010129 (NIH – National Institute On Aging)
P50AG005134 (NIH – National Institute On Aging)
P30AG066444 (NIH – National Institute On Aging)
P50AG005138 (NIH – National Institute On Aging)
R01AG028786 (NIH – National Institute On Aging)
U01AG046152 (NIH – National Institute On Aging)
R01AG030146 (NIH – National Institute On Aging)
P30AG010133 (NIH – National Institute On Aging)
R01AG015819 (NIH – National Institute On Aging)
P50AG016574 (NIH – National Institute On Aging)
U24AG041689 (NIH – National Institute On Aging)
P01AG019724 (NIH – National Institute On Aging)
U54AG052427 (NIH – National Institute On Aging)
U01AG006781 (NIH – National Institute On Aging)
U01AG032984 (NIH – National Institute On Aging)
R01AG041232 (NIH – National Institute On Aging)
P30AG028377 (NIH – National Institute On Aging)
P01AG003991 (NIH – National Institute On Aging)
U24AG056270 (NIH – National Institute On Aging)
P30AG010161 (NIH – National Institute On Aging)
R01AG048015 (NIH – National Institute On Aging)
R01AG064614 (NIH – National Institute On Aging)
P50AG033514 (NIH – National Institute On Aging)
P50AG005146 (NIH – National Institute On Aging)
R01AG017917 (NIH – National Institute On Aging)
U24AG021886 (NIH – National Institute On Aging)
P50AG005136 (NIH – National Institute On Aging)
R01AG036042 (NIH – National Institute On Aging)
U01AG058654 (NIH – National Institute On Aging)
RC2AG036547 (NIH – National Institute On Aging)
R01AG009956 (NIH – National Institute On Aging)
P50AG016582 (NIH – National Institute On Aging)
R01AG025259 (NIH – National Institute On Aging)
P01AG002219 (NIH – National Institute On Aging)
U24AG026395 (NIH – National Institute On Aging)
R01AG017173 (NIH – National Institute On Aging)
P50AG008671 (NIH – National Institute On Aging)
RC2AG036528 (NIH – National Institute On Aging)
RC2AG036650 (NIH – National Institute On Aging)
RC2AG036502 (NIH – National Institute On Aging)
P01AG010491 (NIH – National Institute On Aging)
P20MD000546 (NIH – National Institute On Minority Health and Health Disparities)
Publication Type:
Article
Unique ID:
10.1002/alz.13880
PMID:
38958117
DOI:
10.1002/alz.13880
Journal:
Alzheimer's and Dementia
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record
View Web of Science Record

Record Created:

Whole genome‐wide sequence analysis of long‐lived families (Long‐Life Family Study) identifies MTUS2 gene associated with late‐onset Alzheimer's disease

Xicota, L., Cosentino, S., Vardarajan, B., Mayeux, R., Perls, T. T., Andersen, S. L., Zmuda, J. M., Thyagarajan, B., Yashin, A., Wojczynski, M. K., Krinsky‐McHale, S., Handen, B. L., Christian, B. T., Head, E., Mapstone, M. E., Schupf, N., Lee, J. H., & Barral, S. (2024). Whole genome‐wide sequence analysis of long‐lived families (Long‐Life Family Study) identifies MTUS2 gene associated with late‐onset Alzheimer’s disease. Alzheimer’s & Dementia, 20(4), 2670–2679. Portico. https://doi.org/10.1002/alz.13718
Authors:
Laura Xicota
Stephanie Cosentino
Badri N. Vardarajan
Richard Mayeux
Thomas T. Perls
Stacy Anderson
Joseph M. Zmuda
Bharat Thyagarajan
Anatoli I. Yashin
Mary K. Wojczynski
Sharon J. Krinsky‐McHale
Benjamin L. Handen
Bradley T. Christian
Elizabeth Head
Mark Mapstone
Nicole Schupf
Joseph H. Lee
Sandra Barral
Affiliated Authors:
Laura Xicota
Stephanie Cosentino
Badri N. Vardarajan
Richard Mayeux
Sharon J. Krinsky‐McHale
Nicole Schupf
Joseph H. Lee
Sandra Barral
Columbia Affiliation:
Subjects:
Alzheimer Disease (MeSH)
Mechanisms of Alzheimer's Disease (OpenAlex Topic)
Diagnosis and Management of Alzheimer's Disease (OpenAlex Topic)
Standards and Guidelines for Genetic Variant Interpretation (OpenAlex Topic)
Author Keywords:
mtus2 gene
genetic risk
late‐onset alzheimer's disease
microtubule protein
whole genome sequence
late-onset alzheimer's disease
Grants:
P50HD105353 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
U54HD087011 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
U54HD090256 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
UL1TR002345 (NIH – National Center for Advancing Translational Sciences)
UL1TR001414 (NIH – National Center for Advancing Translational Sciences)
UL1TR001857 (NIH – National Center for Advancing Translational Sciences)
UL1TR002373 (NIH – National Center for Advancing Translational Sciences)
UL1TR001873 (NIH – National Center for Advancing Translational Sciences)
P30AG072947 (NIH – National Institute On Aging)
P30AG072979 (NIH – National Institute On Aging)
P30AG066507 (NIH – National Institute On Aging)
U01AG032984 (NIH – National Institute On Aging)
R01AG028786 (NIH – National Institute On Aging)
P30AG010161 (NIH – National Institute On Aging)
P20AG068024 (NIH – National Institute On Aging)
RF1AG022018 (NIH – National Institute On Aging)
P30AG066546 (NIH – National Institute On Aging)
R01AG026390 (NIH – National Institute On Aging)
P50AG008702 (NIH – National Institute On Aging)
P30AG072946 (NIH – National Institute On Aging)
U24AG072122 (NIH – National Institute On Aging)
RF1AG066107 (NIH – National Institute On Aging)
P50AG005681 (NIH – National Institute On Aging)
P30AG066512 (NIH – National Institute On Aging)
P30AG072931 (NIH – National Institute On Aging)
P30AG072959 (NIH – National Institute On Aging)
P30AG062677 (NIH – National Institute On Aging)
U01AG023755 (NIH – National Institute On Aging)
P30AG066511 (NIH – National Institute On Aging)
P50AG005133 (NIH – National Institute On Aging)
P30AG066515 (NIH – National Institute On Aging)
R01AG041797 (NIH – National Institute On Aging)
U01AG023746 (NIH – National Institute On Aging)
R01AG079280 (NIH – National Institute On Aging)
U19AG063893 (NIH – National Institute On Aging)
R37AG015473 (NIH – National Institute On Aging)
P30AG066530 (NIH – National Institute On Aging)
R01AG072474 (NIH – National Institute On Aging)
P20AG068053 (NIH – National Institute On Aging)
P30AG066468 (NIH – National Institute On Aging)
U01AG051412 (NIH – National Institute On Aging)
P30AG072972 (NIH – National Institute On Aging)
P30AG066444 (NIH – National Institute On Aging)
U24AG021886 (NIH – National Institute On Aging)
P30AG072958 (NIH – National Institute On Aging)
R01AG015819 (NIH – National Institute On Aging)
U01AG023749 (NIH – National Institute On Aging)
U54AG052427 (NIH – National Institute On Aging)
P30AG066514 (NIH – National Institute On Aging)
P30AG066462 (NIH – National Institute On Aging)
P30AG066518 (NIH – National Institute On Aging)
P30AG066506 (NIH – National Institute On Aging)
U01AG016976 (NIH – National Institute On Aging)
P30AG062715 (NIH – National Institute On Aging)
U01AG051406 (NIH – National Institute On Aging)
P30AG072975 (NIH – National Institute On Aging)
P30AG066509 (NIH – National Institute On Aging)
U19AG068054 (NIH – National Institute On Aging)
P30AG062422 (NIH – National Institute On Aging)
P30AG066508 (NIH – National Institute On Aging)
P30AG072977 (NIH – National Institute On Aging)
U01AG023712 (NIH – National Institute On Aging)
P30AG072978 (NIH – National Institute On Aging)
R01AG017917 (NIH – National Institute On Aging)
P30AG066519 (NIH – National Institute On Aging)
U01AG023744 (NIH – National Institute On Aging)
P30AG062429 (NIH – National Institute On Aging)
P20AG068082 (NIH – National Institute On Aging)
U24AG041689 (NIH – National Institute On Aging)
P20AG068077 (NIH – National Institute On Aging)
P30AG062421 (NIH – National Institute On Aging)
R01AG037212 (NIH – National Institute On Aging)
P30AG072976 (NIH – National Institute On Aging)
P30AG072973 (NIH – National Institute On Aging)
RC2AG036528 (NIH – National Institute On Aging)
U24AG026395 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1002/alz.13718
PMID:
38380866
DOI:
10.1002/alz.13718
Journal:
Alzheimer's and Dementia
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
View PubMed Record
View Scopus Record
View Web of Science Record

Record Created:

Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease

Jun, G. R., You, Y., Zhu, C., Meng, G., Chung, J., Panitch, R., Hu, J., Xia, W., Bennett, D. A., Foroud, T. M., Wang, L., Haines, J. L., Mayeux, R., Pericak‐Vance, M. A., Schellenberg, G. D., Au, R., Lunetta, K. L., Ikezu, T., … Farrer, L. A. (2022). Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer’s disease. Alzheimer’s & Dementia, 18(11), 2042–2054. Portico. https://doi.org/10.1002/alz.12607
Authors:
Gyungah R. Jun
Yang You
Congcong Zhu
Gaoyuan Meng
Jaeyoon Chung
Rebecca Panitch
Junming Hu
Weiming Xia
David A. Bennett
Tatiana M. Foroud
Li-San Wang
Jonathan L. Haines
Richard Mayeux
Margaret A. Pericak-Vance
Gerard D. Schellenberg
Rhoda Au
Kathryn L. Lunetta
Tsuneya Ikezu
Thor D. Stein
Lindsay A. Farrer
Affiliated Authors:
Richard Mayeux
Columbia Affiliation:
Author Keywords:
alzheimer's disease
apolipoprotein e
c4b
human induced pluripotent stem cells
ppp2cb
tau protein
Grants:
R01CA129769 (NIH – National Cancer Institute)
R01CA109650 (NIH – National Cancer Institute)
KL2RR024151 (NIH – National Center for Research Resources)
UL1RR029893 (NIH – National Center for Research Resources)
U01HG006375 (NIH – National Human Genome Research Institute)
U01HG008657 (NIH – National Human Genome Research Institute)
U01HG004610 (NIH – National Human Genome Research Institute)
R01MH080295 (NIH – National Institute of Mental Health)
P50MH060451 (NIH – National Institute of Mental Health)
R01NS059873 (NIH – National Institute of Neurological Disorders and Stroke)
R21NS104609 (NIH – National Institute of Neurological Disorders and Stroke)
P50NS039764 (NIH – National Institute of Neurological Disorders and Stroke)
P50AG005146 (NIH – National Institute On Aging)
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R01AG041797 (NIH – National Institute On Aging)
R01AG015819 (NIH – National Institute On Aging)
P30AG062422 (NIH – National Institute On Aging)
U24AG041689 (NIH – National Institute On Aging)
P50AG005136 (NIH – National Institute On Aging)
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R01AG022374 (NIH – National Institute On Aging)
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U19AG068753 (NIH – National Institute On Aging)
P50AG016570 (NIH – National Institute On Aging)
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U01AG010483 (NIH – National Institute On Aging)
U01AG032984 (NIH – National Institute On Aging)
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R01AG022018 (NIH – National Institute On Aging)
U24AG021886 (NIH – National Institute On Aging)
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RC2AG036502 (NIH – National Institute On Aging)
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Publication Type:
Article
Unique ID:
10.1002/alz.12607
PMID:
35142023
DOI:
10.1002/alz.12607
Journal:
Alzheimer's and Dementia
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View Web of Science Record

Record Created:

CSV