Poly(ADP-ribose) Polymerase Inhibitors

Displaying 1 - 8 of 8CSV
Pappas, K., Ferrari, M., Smith, P., Nandakumar, S., Khan, Z., Young, S. B., LaClair, J., Russo, M. V., Huang-Hobbs, E., Schultz, N., Abida, W., Karthaus, W., Jasin, M., & L. Sawyers, C. (2025). BRCA2 reversion mutation–independent resistance to PARP inhibition through impaired DNA prereplication complex function. Proceedings of the National Academy of Sciences, 122(23). https://doi.org/10.1073/pnas.2426743122
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Tai, Y., Chow, A., Han, S., Coker, C., Ma, W., Gu, Y., Estrada Navarro, V., Kandpal, M., Hibshoosh, H., Kalinsky, K., Manova-Todorova, K., Safonov, A., Walsh, E. M., Robson, M., Norton, L., Baer, R., Merghoub, T., Biswas, A. K., & Acharyya, S. (2024). FLT1 activation in cancer cells promotes PARP-inhibitor resistance in breast cancer. EMBO Molecular Medicine, 16(8), 1957–1980. https://doi.org/10.1038/s44321-024-00094-2
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Boila, L. D., Ghosh, S., Bandyopadhyay, S. K., Jin, L., Murison, A., Zeng, A. G. X., Shaikh, W., Bhowmik, S., Muddineni, S. S. N. A., Biswas, M., Sinha, S., Chatterjee, S. S., Mbong, N., Gan, O. I., Bose, A., Chakraborty, S., Arruda, A., Kennedy, J. A., Mitchell, A., … Sengupta, A. (2023). KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition. Leukemia, 37(4), 751–764. https://doi.org/10.1038/s41375-023-01833-z
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Hayward, S. B., & Ciccia, A. (2021). Towards a CRISPeR understanding of homologous recombination with high-throughput functional genomics. Current Opinion in Genetics & Development, 71, 171–181. https://doi.org/10.1016/j.gde.2021.08.006
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