KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition

Boila, L. D., Ghosh, S., Bandyopadhyay, S. K., Jin, L., Murison, A., Zeng, A. G. X., Shaikh, W., Bhowmik, S., Muddineni, S. S. N. A., Biswas, M., Sinha, S., Chatterjee, S. S., Mbong, N., Gan, O. I., Bose, A., Chakraborty, S., Arruda, A., Kennedy, J. A., Mitchell, A., … Sengupta, A. (2023). KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition. Leukemia, 37(4), 751–764. https://doi.org/10.1038/s41375-023-01833-z
Authors:
Liberalis Debraj Boila
Subhadeep Ghosh
Subham K Bandyopadhyay
Liqing Jin
Alex Murison
Andy G X Zeng
Wasim Shaikh
Satyaki Bhowmik
Siva Sai Naga Anurag Muddineni
Mayukh Biswas
Sayantani Sinha
Shankha Subhra Chatterjee
Nathan Mbong
Olga I Gan
Anwesha Bose
Sayan Chakraborty
Andrea Arruda
James A Kennedy
Amanda Mitchell
Eric R Lechman
Debasis Banerjee
Michael Milyavsky
Mark D Minden
John E Dick
Amitava Sengupta
Affiliated Authors:
Mayukh Biswas
Publication Type:
Article
Unique ID:
10.1038/s41375-023-01833-z
PMID:
Journal:
Publication Date:
Data Source:
PubMed

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