Piperazines
Brenner, I. R., Flanagan, C. F., Penazzato, M., Webb, K. A., Horsfall, S. B., Hyle, E. P., Abrams, E., Bacha, J., Neilan, A. M., Collins, I. J., Desmonde, S., Crichton, S., Davies, M.-A., Freedberg, K. A., & Ciaranello, A. L. (2024). Cost-effectiveness of viral load testing for transitioning antiretroviral therapy-experienced children to dolutegravir in South Africa: a modelling analysis. The Lancet Global Health, 12(12), e2068–e2079. https://doi.org/10.1016/s2214-109x(24)00381-4
Publication Date
Columbia Affiliation
Jhaveri, K. L., Accordino, M. K., Bedard, P. L., Cervantes, A., Gambardella, V., Hamilton, E., Italiano, A., Kalinsky, K., Krop, I. E., Oliveira, M., Schmid, P., Saura, C., Turner, N. C., Varga, A., Cheeti, S., Hilz, S., Hutchinson, K. E., Jin, Y., Royer-Joo, S., … Juric, D. (2024). Phase I/Ib Trial of Inavolisib Plus Palbociclib and Endocrine Therapy for PIK3CA-Mutated, Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Advanced or Metastatic Breast Cancer. Journal of Clinical Oncology, 42(33), 3947–3956. https://doi.org/10.1200/jco.24.00110
Publication Date
Columbia Affiliation
Abrams, E. J., Jao, J., Madlala, H. P., Zerbe, A., Catalano, P., Gerschenson, M., Goedecke, J. H., Gomba, Y., Josefson, J., Kurland, I. J., Legbedze, J., McComsey, G. A., Matyesini, S., Mukonda, E., Robinson, D., & Myer, L. (2024). An observational cohort study to investigate the impact of dolutegravir in pregnancy and its obesogenic effects on the metabolic health of women living with HIV and their children: Study protocol. PLOS ONE, 19(8), e0307296. https://doi.org/10.1371/journal.pone.0307296
Publication Date
Columbia Affiliation
Fojo, T., LaRose, M., & Bates, S. E. (2024). The Impact of Exuberance on Equipoise in Oncology Clinical Trials: Sotorasib as Archetype. The Oncologist, 29(4), 275–277. https://doi.org/10.1093/oncolo/oyae042
Publication Date
Columbia Affiliation
Mok, S., & Fidock, D. A. (2024). Determinants of piperaquine-resistant malaria in South America. The Lancet Infectious Diseases, 24(2), 114–116. https://doi.org/10.1016/s1473-3099(23)00564-9
Publication Date
Columbia Affiliation
Hagenah, L. M., Dhingra, S. K., Small-Saunders, J. L., Qahash, T., Willems, A., Schindler, K. A., Rangel, G. W., Gil-Iturbe, E., Kim, J., Akhundova, E., Yeo, T., Okombo, J., Mancia, F., Quick, M., Roepe, P. D., Llinás, M., & Fidock, D. A. (2024). Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered
Plasmodium falciparum
physiology. MBio, 15(1). https://doi.org/10.1128/mbio.01832-23
Publication Date
Columbia Affiliation
Vagelos College of Physicians and Surgeons; Department of Microbiology and Immunology; Department of Physiology and Cellular Biophysics; Department of Psychiatry; Division of Molecular Therapeutics; Center for Malaria Therapeutics and Antimicrobial Resistance; Division of Infectious Diseases; Department of Medicine
Ayaz, P., Lyczek, A., Paung, Y., Mingione, V. R., Iacob, R. E., de Waal, P. W., Engen, J. R., Seeliger, M. A., Shan, Y., & Shaw, D. E. (2023). Structural mechanism of a drug-binding process involving a large conformational change of the protein target. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-36956-5
Publication Date
Columbia Affiliation
View
Langelier, M.-F., Lin, X., Zha, S., & Pascal, J. M. (2023). Clinical PARP inhibitors allosterically induce PARP2 retention on DNA. Science Advances, 9(12). https://doi.org/10.1126/sciadv.adf7175
Publication Date
Columbia Affiliation
Small-Saunders, J. L., Hagenah, L. M., Wicht, K. J., Dhingra, S. K., Deni, I., Kim, J., Vendome, J., Gil-Iturbe, E., Roepe, P. D., Mehta, M., Mancia, F., Quick, M., Eppstein, M. J., & Fidock, D. A. (2022). Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance. PLOS Pathogens, 18(2), e1010278. https://doi.org/10.1371/journal.ppat.1010278
Publication Date
Columbia Affiliation
Vagelos College of Physicians and Surgeons; Department of Physiology and Cellular Biophysics; Department of Psychiatry; Division of Molecular Therapeutics; Center for Malaria Therapeutics and Antimicrobial Resistance; Division of Infectious Diseases; Department of Medicine; Department of Microbiology and Immunology
Kantrowitz, J. T. (2021). Additional perspective on cariprazine and negative symptoms. Expert Opinion on Pharmacotherapy, 23(12), 1469–1470. https://doi.org/10.1080/14656566.2021.1968828
Publication Date
Columbia Affiliation
Gunaratne, S. H., Tieu, H. V., Wilkin, T. J., & Taylor, B. S. (2021). CROI 2021: Advances in Antiretroviral Therapy for HIV and Antiviral Therapy for COVID-19. Topics in antiviral medicine, 29(3), 361–378.
Publication Date
Columbia Affiliation
View