Drug Discovery

Displaying 1 - 6 of 6CSV
Syphers, J. L., Wright, J. A., Liu, S., Gee, Y. S., Gao, F., Mudududdla, R., Che, D. Q., Chang, A., Sloan, E. K., Narasimhan, V., Heriot, A., Ramsay, R. G., de Nys, R., Silva, T. N., Vrbanac, L., Sammour, T., Lawrence, M. J., Tin, T., Maddern, G. J., … Baell, J. B. (2025). Discovery of WEE1 Kinase Inhibitors with Potent Activity against Patient-Derived, Metastatic Colorectal Cancer Organoids. Journal of Medicinal Chemistry, 68(8), 8065–8090. https://doi.org/10.1021/acs.jmedchem.4c02541
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Teles, D., & Fine, B. M. (2024). Using induced pluripotent stem cells for drug discovery in arrhythmias. Expert Opinion on Drug Discovery, 19(7), 827–840. https://doi.org/10.1080/17460441.2024.2360420
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Rajbhandari, P., Neelakantan, T. V., Hosny, N., & Stockwell, B. R. (2024). Spatial pharmacology using mass spectrometry imaging. Trends in Pharmacological Sciences, 45(1), 67–80. https://doi.org/10.1016/j.tips.2023.11.003
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Lin, W., Gandhi, S., Bhattarai, P., Kasa, K., Kizil, C., & Zhang, Y. (2023). Combining high throughput array synthesis and growth algorithm to discover TNF-α binders with new structures and properties. European Journal of Medicinal Chemistry, 248, 115078. https://doi.org/10.1016/j.ejmech.2022.115078
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Mishra, A., Malik, R., Hachiya, T., Jürgenson, T., Namba, S., Posner, D. C., Kamanu, F. K., Koido, M., Le Grand, Q., Shi, M., He, Y., Georgakis, M. K., Caro, I., Krebs, K., Liaw, Y.-C., Vaura, F. C., Lin, K., Winsvold, B. S., Srinivasasainagendra, V., … Debette, S. (2022). Stroke genetics informs drug discovery and risk prediction across ancestries. Nature, 611(7934), 115–123. https://doi.org/10.1038/s41586-022-05165-3
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