Histones

Displaying 1 - 32 of 32CSV
Vann, K. R., Sharma, R., Hsu, C.-C., Devoucoux, M., Tencer, A. H., Zeng, L., Lin, K., Zhu, L., Li, Q., Lachance, C., Ospina, R. R., Tong, Q., Cheung, K. L., Yang, S., Biswas, S., Xuan, H., Gatchalian, J., Alamillo, L., Wang, J., … Kutateladze, T. G. (2025). Structure-function relationship of ASH1L and histone H3K36 and H3K4 methylation. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-57556-5
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Duan, S., Nodelman, I. M., Zhou, H., Tsukiyama, T., Bowman, G. D., & Zhang, Z. (2025). H3K56 acetylation regulates chromatin maturation following DNA replication. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55144-7
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Shipman, G. A., Padilla, R., Horth, C., Hu, B., Bareke, E., Vitorino, F. N., Gongora, J. M., Garcia, B. A., Lu, C., & Majewski, J. (2024). Systematic perturbations of SETD2, NSD1, NSD2, NSD3, and ASH1L reveal their distinct contributions to H3K36 methylation. Genome Biology, 25(1). https://doi.org/10.1186/s13059-024-03415-3
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Gretarsson, K. H., Abini-Agbomson, S., Gloor, S. L., Weinberg, D. N., McCuiston, J. L., Kumary, V. U. S., Hickman, A. R., Sahu, V., Lee, R., Xu, X., Lipieta, N., Flashner, S., Adeleke, O. A., Popova, I. K., Taylor, H. F., Noll, K., Windham, C. L., Maryanski, D. N., Venters, B. J., … Lu, C. (2024). Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch. Science Advances, 10(35). https://doi.org/10.1126/sciadv.adp0975
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Serra-Cardona, A., Hua, X., McNutt, S. W., Zhou, H., Toda, T., Jia, S., Chu, F., & Zhang, Z. (2024). The PCNA–Pol δ complex couples lagging strand DNA synthesis to parental histone transfer for epigenetic inheritance. Science Advances, 10(23). https://doi.org/10.1126/sciadv.adn5175
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Watanabe, J., Clutter, M. R., Gullette, M. J., Sasaki, T., Uchida, E., Kaur, S., Mo, Y., Abe, K., Ishi, Y., Takata, N., Natsumeda, M., Gadd, S., Zhang, Z., Becher, O. J., & Hashizume, R. (2024). BET bromodomain inhibition potentiates radiosensitivity in models of H3K27-altered diffuse midline glioma. Journal of Clinical Investigation, 134(13). https://doi.org/10.1172/jci174794
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Fang, Y., Hua, X., Shan, C.-M., Toda, T., Qiao, F., Zhang, Z., & Jia, S. (2024). Coordination of histone chaperones for parental histone segregation and epigenetic inheritance. Genes & Development, 38(3–4), 189–204. https://doi.org/10.1101/gad.351278.123
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Gan, S., Yang, W.-S., Wei, L., Zhang, Z., & Xu, R.-M. (2024). Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2. Science China Life Sciences, 67(6), 1305–1307. https://doi.org/10.1007/s11427-024-2560-8
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Arrillaga-Romany, I., Gardner, S. L., Odia, Y., Aguilera, D., Allen, J. E., Batchelor, T., Butowski, N., Chen, C., Cloughesy, T., Cluster, A., de Groot, J., Dixit, K. S., Graber, J. J., Haggiagi, A. M., Harrison, R. A., Kheradpour, A., Kilburn, L. B., Kurz, S. C., Lu, G., … Wen, P. Y. (2024). ONC201 (Dordaviprone) in Recurrent H3 K27M–Mutant Diffuse Midline Glioma. Journal of Clinical Oncology, 42(13), 1542–1552. https://doi.org/10.1200/jco.23.01134
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Basavarajappa, B. S., & Subbanna, S. (2024). Unlocking the Epigenetic Symphony: Histone Acetylation’s Impact on Neurobehavioral Change in Neurodegenerative Disorders. Epigenomics, 16(5), 331–358. https://doi.org/10.2217/epi-2023-0428
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Mendelson, K., Martin, T. C., Nguyen, C. B., Hsu, M., Xu, J., Lang, C. C. V., Dummer, R., Saenger, Y., Messina, J. L., Sondak, V. K., Desman, G., Hasson, D., Bernstein, E., Parsons, R. E., & Celebi, J. T. (2024). Differential histone acetylation and super-enhancer regulation underlie melanoma cell dedifferentiation. JCI Insight. https://doi.org/10.1172/jci.insight.166611
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Giacomini, G., Piquet, S., Chevallier, O., Dabin, J., Bai, S.-K., Kim, B., Siddaway, R., Raught, B., Coyaud, E., Shan, C.-M., Reid, R. J. D., Toda, T., Rothstein, R., Barra, V., Wilhelm, T., Hamadat, S., Bertin, C., Crane, A., Dubois, F., … Polo, S. E. (2024). Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors. Nucleic Acids Research, 52(5), 2372–2388. https://doi.org/10.1093/nar/gkad1257
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Li, A. M., He, B., Karagiannis, D., Li, Y., Jiang, H., Srinivasan, P., Ramirez, Y., Zhou, M.-N., Curtis, C., Gruber, J. J., Lu, C., Rankin, E. B., & Ye, J. (2023). Serine starvation silences estrogen receptor signaling through histone hypoacetylation. Proceedings of the National Academy of Sciences, 120(38). https://doi.org/10.1073/pnas.2302489120
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Liu, C.-P., Yu, Z., Xiong, J., Hu, J., Song, A., Ding, D., Yu, C., Yang, N., Wang, M., Yu, J., Hou, P., Zeng, K., Li, Z., Zhang, Z., Zhang, X., Li, W., Zhang, Z., Zhu, B., Li, G., & Xu, R.-M. (2023). Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381(6660). https://doi.org/10.1126/science.add8673
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Abini-Agbomson, S., Gretarsson, K., Shih, R. M., Hsieh, L., Lou, T., De Ioannes, P., Vasilyev, N., Lee, R., Wang, M., Simon, M. D., Armache, J.-P., Nudler, E., Narlikar, G., Liu, S., Lu, C., & Armache, K.-J. (2023). Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1. Molecular Cell, 83(16), 2872-2883.e7. https://doi.org/10.1016/j.molcel.2023.07.020
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Bacon, B., Repin, M., Shuryak, I., Wu, H., Santella, R. M., Terry, M. B., Brenner, D. J., & Turner, H. C. (2023). High‐throughput measurement of double strand break global repair phenotype in peripheral blood mononuclear cells after long‐term cryopreservation. Cytometry Part A, 103(7), 575–583. Portico. https://doi.org/10.1002/cyto.a.24725
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Wang, Y.-C., Kelso, A. A., Karamafrooz, A., Chen, Y.-H., Chen, W.-K., Cheng, C.-T., Qi, Y., Gu, L., Malkas, L., Taglialatela, A., Kung, H.-J., Moldovan, G.-L., Ciccia, A., Stark, J. M., & Ann, D. K. (2023). Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination. Cell Reports, 42(4), 112296. https://doi.org/10.1016/j.celrep.2023.112296
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Khazaei, S., Chen, C. C. L., Andrade, A. F., Kabir, N., Azarafshar, P., Morcos, S. M., França, J. A., Lopes, M., Lund, P. J., Danieau, G., Worme, S., Adnani, L., Nzirorera, N., Chen, X., Yogarajah, G., Russo, C., Zeinieh, M., Wong, C. J., Bryant, L., … Jabado, N. (2023). Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration. Cell, 186(6), 1162-1178.e20. https://doi.org/10.1016/j.cell.2023.02.023
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Alves, C. A. P. F., Sherbini, O., D’Arco, F., Steel, D., Kurian, M. A., Radio, F. C., Ferrero, G. B., Carli, D., Tartaglia, M., Balci, T. B., Powell-Hamilton, N. N., Schrier Vergano, S. A., Reutter, H., Hoefele, J., Günthner, R., Roeder, E. R., Littlejohn, R. O., Lessel, D., Lüttgen, S., … Vanderver, A. (2022). Brain Abnormalities in Patients with Germline Variants inH3F3: Novel Imaging Findings and Neurologic Symptoms Beyond Somatic Variants and Brain Tumors. American Journal of Neuroradiology, 43(7), 1048–1053. https://doi.org/10.3174/ajnr.a7555
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Chen, H., Hu, B., Horth, C., Bareke, E., Rosenbaum, P., Kwon, S. Y., Sirois, J., Weinberg, D. N., Robison, F. M., Garcia, B. A., Lu, C., Pastor, W. A., & Majewski, J. (2022). H3K36 dimethylation shapes the epigenetic interaction landscape by directing repressive chromatin modifications in embryonic stem cells. Genome Research. https://doi.org/10.1101/gr.276383.121
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Garrido, A., Kim, E., Teijeiro, A., Sánchez Sánchez, P., Gallo, R., Nair, A., Matamala Montoya, M., Perna, C., Vicent, G. P., Muñoz, J., Campos-Olivas, R., Melms, J. C., Izar, B., Schwabe, R. F., & Djouder, N. (2022). Histone acetylation of bile acid transporter genes plays a critical role in cirrhosis. Journal of Hepatology, 76(4), 850–861. https://doi.org/10.1016/j.jhep.2021.12.019
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Evrin, C., Serra‐Cardona, A., Duan, S., Mukherjee, P. P., Zhang, Z., & Labib, K. P. M. (2022). Spt5 histone binding activity preserves chromatin during transcription by RNA polymerase II. The EMBO Journal, 41(5). Portico. https://doi.org/10.15252/embj.2021109783
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Martinez-Pastor, B., Silveira, G. G., Clarke, T. L., Chung, D., Gu, Y., Cosentino, C., Davidow, L. S., Mata, G., Hassanieh, S., Salsman, J., Ciccia, A., Bae, N., Bedford, M. T., Megias, D., Rubin, L. L., Efeyan, A., Dellaire, G., & Mostoslavsky, R. (2021). Assessing kinetics and recruitment of DNA repair factors using high content screens. Cell Reports, 37(13), 110176. https://doi.org/10.1016/j.celrep.2021.110176
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