Recurrent RhoGAP gene fusion CLDN18-ARHGAP26 promotes RHOA activation and focal adhesion kinase and YAP-TEAD signalling in diffuse gastric cancer

Zhang, F., Sahu, V., Peng, K., Wang, Y., Li, T., Bala, P., Aitymbayev, D., Sahgal, P., Schaefer, A., Der, C. J., Ryeom, S., Yoon, S., Sethi, N., Bass, A. J., & Zhang, H. (2024). Recurrent RhoGAP gene fusion CLDN18-ARHGAP26 promotes RHOA activation and focal adhesion kinase and YAP-TEAD signalling in diffuse gastric cancer. Gut, 73(8), 1280–1291. https://doi.org/10.1136/gutjnl-2023-329686
Authors:
Feifei Zhang
Varun Sahu
Ke Peng
Yichen Wang
Tianxia Li
Pratyusha Bala
Daulet Aitymbayev
Pranshu Sahgal
Antje Schaefer
Channing J. Der
Sandra Ryeom
Sam S. Yoon
Nilay S. Sethi
Adam J. Bass
Haisheng Zhang
Affiliated Authors:
Varun Sahu
Tianxia Li
Sandra Ryeom
Sam S. Yoon
Adam J. Bass
Columbia Affiliation:
Subjects:
Stomach Neoplasms (MeSH)
GTPase-Activating Proteins (MeSH)
rhoA GTP-Binding Protein (MeSH)
Claudins (MeSH)
Signal Transduction (MeSH)
Mice, Transgenic (MeSH)
YAP-Signaling Proteins (MeSH)
Transcription Factors (MeSH)
Role of Hippo Signaling Pathway in Mechanotransduction (OpenAlex Topic)
Protein Arginine Methylation in Mammals (OpenAlex Topic)
mTOR Signaling in Growth and Disease (OpenAlex Topic)
Author Keywords:
gastric cancer
molecular oncology
elink
Publication Type:
Article
Unique ID:
10.1136/gutjnl-2023-329686
PMID:
38621923
DOI:
10.1136/gutjnl-2023-329686
Journal:
Gut
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
View PubMed Record
View Scopus Record
View Web of Science Record

Record Created: