Contributions of major tau kinase activation and phospho-tau accumulation to cortical and hippocampal tangle formation and cognition in older adults

Hernández-Hernández, E., Petyuk, V. A., Valor-Blanquer, J., Yáñez-Gómez, F., Barr, A. M., De Jager, P. L., Chen, E.-Y., Leurgans, S. E., Schneider, J. A., Bennett, D. A., Honer, W. G., García-Fuster, M. J., & Ramos-Miguel, A. (2025). Contributions of major tau kinase activation and phospho-tau accumulation to cortical and hippocampal tangle formation and cognition in older adults. Neurobiology of Disease, 210, 106924. https://doi.org/10.1016/j.nbd.2025.106924
Authors:
Elena Hernández-Hernández
Vladislav A Petyuk
Júlia Valor-Blanquer
Fernando Yáñez-Gómez
Alasdair M Barr
Philip L De Jager
Er-Yun Chen
Sue E Leurgans
Julie A Schneider
David A Bennett
William G Honer
M Julia García-Fuster
Alfredo Ramos-Miguel
Affiliated Authors:
Philip L De Jager
Author Keywords:
alzheimer's disease
cdk-5
erk1/2
gsk-3beta
human brain
neurofibrillary tangles
phosphotau
tau kinase
working memory
p25/p35
Publication Type:
Article
Unique ID:
10.1016/j.nbd.2025.106924
PMID:
Publication Date:
Data Source:
PubMed

Record Created: