PLOS Pathogens
Displaying 1 - 14 of 14
Rawat, M., Padalino, G., Adika, E., Okombo, J., Yeo, T., Brancale, A., Fidock, D. A., Hoffmann, K. F., & Lee, M. C. S. (2025). Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity. PLOS Pathogens, 21(2), e1012216. https://doi.org/10.1371/journal.ppat.1012216
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Columbia Affiliation
Xie, S. C., Tai, C.-W., Morton, C. J., Ma, L., Huang, S.-C., Wittlin, S., Du, Y., Hu, Y., Dogovski, C., Salimimarand, M., Griffin, R., England, D., de la Cruz, E., Deni, I., Yeo, T., Burkhard, A. Y., Striepen, J., Schindler, K. A., Crespo, B., … Tilley, L. (2024). A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo. PLOS Pathogens, 20(12), e1012429. https://doi.org/10.1371/journal.ppat.1012429
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Columbia Affiliation
Ferreira, L. T., Cassiano, G. C., Alvarez, L. C. S., Okombo, J., Calit, J., Fontinha, D., Gil-Iturbe, E., Coyle, R., Andrade, C. H., Sunnerhagen, P., Bargieri, D. Y., Prudêncio, M., Quick, M., Cravo, P. V., Lee, M. C. S., Fidock, D. A., & Costa, F. T. M. (2024). A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants. PLOS Pathogens, 20(10), e1012627. https://doi.org/10.1371/journal.ppat.1012627
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Columbia Affiliation
Vagelos College of Physicians and Surgeons; Department of Microbiology and Immunology; Department of Psychiatry; Division of Molecular Therapeutics; Department of Physiology and Cellular Biophysics; Center for Malaria Therapeutics and Antimicrobial Resistance; Department of Medicine; Division of Infectious Diseases
Bobba, S., Chauhan, K. S., Akter, S., Das, S., Mittal, E., Mathema, B., Philips, J. A., & Khader, S. A. (2024). A protective role for type I interferon signaling following infection with Mycobacterium tuberculosis carrying the rifampicin drug resistance-conferring RpoB mutation H445Y. PLOS Pathogens, 20(4), e1012137. https://doi.org/10.1371/journal.ppat.1012137
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Columbia Affiliation
Joseph, S. B., Abrahams, M.-R., Moeser, M., Tyers, L., Archin, N. M., Council, O. D., Sondgeroth, A., Spielvogel, E., Emery, A., Zhou, S., Doolabh, D., Ismail, S. D., Karim, S. A., Margolis, D. M., Pond, S. K., Garrett, N., Swanstrom, R., & Williamson, C. (2024). The timing of HIV-1 infection of cells that persist on therapy is not strongly influenced by replication competency or cellular tropism of the provirus. PLOS Pathogens, 20(2), e1011974. https://doi.org/10.1371/journal.ppat.1011974
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Columbia Affiliation
Berton, R. R., McGonagil, P. W., Jensen, I. J., Ybarra, T. K., Bishop, G. A., Harty, J. T., Griffith, T. S., & Badovinac, V. P. (2023). Sepsis leads to lasting changes in phenotype and function of naïve CD8 T cells. PLOS Pathogens, 19(10), e1011720. https://doi.org/10.1371/journal.ppat.1011720
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Columbia Affiliation
Ou, L., Chen, S. J., Teng, I.-T., Yang, L., Zhang, B., Zhou, T., Biju, A., Cheng, C., Kong, W.-P., Morano, N. C., Stancofski, E.-S. D., Todd, J.-P., Tsybovsky, Y., Wang, S., Zheng, C.-Y., Mascola, J. R., Shapiro, L., Woodward, R. A., Buchholz, U. J., & Kwong, P. D. (2023). Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus. PLOS Pathogens, 19(9), e1011584. https://doi.org/10.1371/journal.ppat.1011584
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Columbia Affiliation
Maximova, O. A., Weller, M. L., Krogmann, T., Sturdevant, D. E., Ricklefs, S., Virtaneva, K., Martens, C., Wollenberg, K., Minai, M., Moore, I. N., Sauter, C. S., Barker, J. N., Lipkin, W. I., Seilhean, D., Nath, A., & Cohen, J. I. (2023). Pathogenesis and outcome of VA1 astrovirus infection in the human brain are defined by disruption of neural functions and imbalanced host immune responses. PLOS Pathogens, 19(8), e1011544. https://doi.org/10.1371/journal.ppat.1011544
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Columbia Affiliation
Kucharski, M., Wirjanata, G., Nayak, S., Boentoro, J., Dziekan, J. M., Assisi, C., van der Pluijm, R. W., Miotto, O., Mok, S., Dondorp, A. M., & Bozdech, Z. (2023). Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmodium falciparum. PLOS Pathogens, 19(1), e1011118. https://doi.org/10.1371/journal.ppat.1011118
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Columbia Affiliation
Zhang, B., Huang, W., Pei, S., Zeng, J., Shen, W., Wang, D., Wang, G., Chen, T., Yang, L., Cheng, P., Wang, D., Shu, Y., & Du, X. (2022). Mechanisms for the circulation of influenza A(H3N2) in China: A spatiotemporal modelling study. PLOS Pathogens, 18(12), e1011046. https://doi.org/10.1371/journal.ppat.1011046
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Columbia Affiliation
Okombo, J., Mok, S., Qahash, T., Yeo, T., Bath, J., Orchard, L. M., Owens, E., Koo, I., Albert, I., Llinás, M., & Fidock, D. A. (2022). Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages. PLOS Pathogens, 18(10), e1010926. https://doi.org/10.1371/journal.ppat.1010926
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Columbia Affiliation
Morris, S. E., Strehlau, R., Shiau, S., Abrams, E. J., Tiemessen, C. T., Kuhn, L., & Yates, A. J. (2022). Healthy dynamics of CD4 T cells may drive HIV resurgence in perinatally-infected infants on antiretroviral therapy. PLOS Pathogens, 18(8), e1010751. https://doi.org/10.1371/journal.ppat.1010751
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Columbia Affiliation
Palrasu, M., Zaika, E., Paulrasu, K., Caspa Gokulan, R., Suarez, G., Que, J., El-Rifai, W., Peek, R. M., Garcia-Buitrago, M., & Zaika, A. I. (2022). Helicobacter pylori pathogen inhibits cellular responses to oncogenic stress and apoptosis. PLOS Pathogens, 18(6), e1010628. https://doi.org/10.1371/journal.ppat.1010628
Publication Date
Columbia Affiliation
Small-Saunders, J. L., Hagenah, L. M., Wicht, K. J., Dhingra, S. K., Deni, I., Kim, J., Vendome, J., Gil-Iturbe, E., Roepe, P. D., Mehta, M., Mancia, F., Quick, M., Eppstein, M. J., & Fidock, D. A. (2022). Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance. PLOS Pathogens, 18(2), e1010278. https://doi.org/10.1371/journal.ppat.1010278
Publication Date
Columbia Affiliation
Vagelos College of Physicians and Surgeons; Department of Physiology and Cellular Biophysics; Department of Psychiatry; Division of Molecular Therapeutics; Center for Malaria Therapeutics and Antimicrobial Resistance; Division of Infectious Diseases; Department of Medicine; Department of Microbiology and Immunology