R01EY032507

NIH – National Eye Institute

In Vivo Quantification of Anterior and Posterior Chamber Volumes in Mice: Implications for Aqueous Humor Dynamics

Kim, D., Fang, R., Zhang, P., Yan, Z., Sun, C., Li, G., Montgomery, C., John, S. W. M., Stamer, W. D., Zhang, H. F., & Ethier, C. R. (2025). In Vivo Quantification of Anterior and Posterior Chamber Volumes in Mice: Implications for Aqueous Humor Dynamics. Investigative Ophthalmology & Visual Science, 66(1), 18. https://doi.org/10.1167/iovs.66.1.18

Authors:

Daniel Kim

Raymond Fang

Pengpeng Zhang

Zihang Yan

Cheng Sun

Guorong Li

Christa Montgomery

Simon W M John

W Daniel Stamer

Hao F Zhang

C Ross Ethier

Affiliated Authors:

Christa Montgomery

Simon W M John

Columbia Affiliation:

Subjects:

Aqueous Humor (MeSH)

Tomography, Optical Coherence (MeSH)

Anterior Chamber (MeSH)

Mice, Inbred BALB C (MeSH)

Mice, Inbred C57BL (MeSH)

Author Keywords:

anterior chamber

aqueous humor

imaging

optical coherence tomography (oct)

posterior chamber

animal experiment

animal model

animal tissue

anterior eye chamber

anterior eye chamber volume

aqueous humor flow

article

c57bl 6 mouse

c57bl mouse

computer assisted tomography

controlled study

drug therapy

ex vivo study

female

fluorophotometry

histology

human

male

micro-computed tomography

mouse

nonhuman

optical coherence tomography

animal

bagg albino mouse

diagnostic imaging

intraocular pressure

metabolism

physiology

posterior eye segment

procedures

animals

mice

mice, inbred balb c

mice, inbred c57bl

tomography, optical coherence

x-ray microtomography

Grants:

F30EY034033 (NIH – National Eye Institute)

P30EY005722 (NIH – National Eye Institute)

P30EY019007 (NIH – National Eye Institute)

R01EY029121 (NIH – National Eye Institute)

R01EY030124 (NIH – National Eye Institute)

R01EY031710 (NIH – National Eye Institute)

R01EY032062 (NIH – National Eye Institute)

R01EY032507 (NIH – National Eye Institute)

R01EY033813 (NIH – National Eye Institute)

R01EY034353 (NIH – National Eye Institute)

R01EY034740 (NIH – National Eye Institute)

R44EY026466 (NIH – National Eye Institute)

U01EY033001 (NIH – National Eye Institute)

Publication Type:

Article

Unique ID:

10.1167/iovs.66.1.18

PMID:

39774626

DOI:

10.1167/iovs.66.1.18

Journal:

Investigative Ophthalmology and Visual Science

Publication Date:

2025-01-08

Data Source:

PubMed

Source Link:

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Record Created:

Tuesday, February 11, 2025 - 13:53

Transcriptomic profiling of Schlemm’s canal cells reveals a lymphatic-biased identity and three major cell states

Balasubramanian, R., Kizhatil, K., Li, T., Tolman, N., Bhandari, A., Clark, G., Bupp-Chickering, V., Kelly, R. A., Zhou, S., Peregrin, J., Simón, M., Montgomery, C., Stamer, W. D., Qian, J., & John, S. W. (2024). Transcriptomic profiling of Schlemm’s canal cells reveals a lymphatic-biased identity and three major cell states. ELife, 13. CLOCKSS. https://doi.org/10.7554/elife.96459

Authors:

Revathi Balasubramanian

Krishnakumar Kizhatil

Taibo Li

Nicholas Tolman

Aakriti Bhandari

Graham Clark

Violet Bupp-Chickering

Ruth A. Kelly

Sally Zhou

John Peregrin

Marina Simón

Christa Montgomery

W. Daniel Stamer

Jiang Qian

Simon W. M. John

Affiliated Authors:

Revathi Balasubramanian

Nicholas Tolman

Aakriti Bhandari

Violet Bupp-Chickering

Sally Zhou

John Peregrin

Marina Simón

Christa Montgomery

Simon W. M. John

Columbia Affiliation:

Subjects:

Endothelial Cells (MeSH)

Gene Expression Profiling (MeSH)

Mice, Inbred C57BL (MeSH)

Lymphangiogenesis in Cancer Metastasis and Disease (OpenAlex Topic)

Molecular Characterization of Colorectal Cancer (OpenAlex Topic)

Biology and Pathology of Keratins and Related Disorders (OpenAlex Topic)

Author Keywords:

cell biology

glaucoma anterior segment

mouse

schlemm's canal

single cell transcriptomics

trabecular meshwork

Grants:

P30EY019007 (NIH – National Eye Institute)

R01EY032507 (NIH – National Eye Institute)

P30EY005722 (NIH – National Eye Institute)

R01EY032062 (NIH – National Eye Institute)

R01EY029548 (NIH – National Eye Institute)

R01EY022359 (NIH – National Eye Institute)

R01EY028175 (NIH – National Eye Institute)

Publication Type:

Article

Unique ID:

10.7554/elife.96459

PMID:

39422453

DOI:

10.7554/elife.96459

Journal:

eLife

Publication Date:

2024-05-09

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

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Record Created:

Wednesday, December 4, 2024 - 13:33

CyclinD2-mediated regulation of neurogenic output from the retinal ciliary margin is perturbed in albinism

Slavi, N., Balasubramanian, R., Lee, M. A., Liapin, M., Oaks-Leaf, R., Peregrin, J., Potenski, A., Troy, C. M., Ross, M. E., Herrera, E., Kosmidis, S., John, S. W. M., & Mason, C. A. (2023). CyclinD2-mediated regulation of neurogenic output from the retinal ciliary margin is perturbed in albinism. Neuron, 111(1), 49-64.e5. https://doi.org/10.1016/j.neuron.2022.10.025

Authors:

Nefeli Slavi

Revathi Balasubramanian

Melissa Ann Lee

Michael Liapin

Rachel Oaks-Leaf

John Peregrin

Anna Potenski

Carol Marie Troy

Margaret Elizabeth Ross

Eloisa Herrera

Stylianos Kosmidis

Simon William Maxwell John

Carol Ann Mason

Affiliated Authors:

Nefeli Slavi

Revathi Balasubramanian

Melissa Ann Lee

Michael Liapin

Rachel Oaks-Leaf

John Peregrin

Anna Potenski

Carol Marie Troy

Stylianos Kosmidis

Simon William Maxwell John

Carol Ann Mason

Columbia Affiliation:

Subjects:

Albinism (MeSH)

Retina (MeSH)

Author Keywords:

albinism

binocular vision

ciliary margin

cyclind2

ipsilateral projection

neurogenesis

retinal ganglion cells

rpe

single-cell rna seq

Grants:

P30CA013696 (NIH – National Cancer Institute)

UL1TR001873 (NIH – National Center for Advancing Translational Sciences)

R01EY012736 (NIH – National Eye Institute)

R01EY032507 (NIH – National Eye Institute)

R01EY015290 (NIH – National Eye Institute)

R21EY023714 (NIH – National Eye Institute)

R01EY032062 (NIH – National Eye Institute)

P30EY019007 (NIH – National Eye Institute)

R01NS105477 (NIH – National Institute of Neurological Disorders and Stroke)

Publication Type:

Article

Unique ID:

10.1016/j.neuron.2022.10.025

PMID:

36351424

DOI:

10.1016/j.neuron.2022.10.025

Journal:

Neuron

Publication Date:

2023-01-04

Data Source:

PubMed

Source Link:

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Record Created:

Friday, August 16, 2024 - 13:01

Mouse models of NADK2 deficiency analyzed for metabolic and gene expression changes to elucidate pathophysiology

Murray, G. C., Bais, P., Hatton, C. L., Tadenev, A. L. D., Hoffmann, B. R., Stodola, T. J., Morelli, K. H., Pratt, S. L., Schroeder, D., Doty, R., Fiehn, O., John, S. W. M., Bult, C. J., Cox, G. A., & Burgess, R. W. (2022). Mouse models of NADK2 deficiency analyzed for metabolic and gene expression changes to elucidate pathophysiology. Human Molecular Genetics, 31(23), 4055–4074. https://doi.org/10.1093/hmg/ddac151

Authors:

G.C. Murray

P. Bais

C.L. Hatton

A.L.D. Tadenev

B.R. Hoffmann

T.J. Stodola

K.H. Morelli

S.L. Pratt

D. Schroeder

R. Doty

O. Fiehn

S.W.M. John

C.J. Bult

G.A. Cox

R.W. Burgess

Affiliated Authors:

S.W.M. John

Columbia Affiliation:

Subjects:

Hyperlysinemias (MeSH)

Neuroaxonal Dystrophies (MeSH)

Grants:

R01EY011721 (NIH – National Eye Institute)

R01EY032507 (NIH – National Eye Institute)

U2CES030158 (NIH – National Institute of Environmental Health Sciences)

T32GM132006 (NIH – National Institute of General Medical Sciences)

R37NS054154 (NIH – National Institute of Neurological Disorders and Stroke)

R21NS082666 (NIH – National Institute of Neurological Disorders and Stroke)

S10OD026816 (NIH – Office of the Director, National Institutes of Health)

Publication Type:

Article

Unique ID:

10.1093/hmg/ddac151

PMID:

35796562

DOI:

10.1093/hmg/ddac151

Journal:

Human Molecular Genetics

Publication Date:

2022-12-01

Data Source:

Scopus

Source Link:

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Record Created:

Thursday, September 12, 2024 - 09:43