Transcriptomic profiling of Schlemm’s canal cells reveals a lymphatic-biased identity and three major cell states

Balasubramanian, R., Kizhatil, K., Li, T., Tolman, N., Bhandari, A., Clark, G., Bupp-Chickering, V., Kelly, R. A., Zhou, S., Peregrin, J., Simón, M., Montgomery, C., Stamer, W. D., Qian, J., & John, S. W. (2024). Transcriptomic profiling of Schlemm’s canal cells reveals a lymphatic-biased identity and three major cell states. ELife, 13. CLOCKSS. https://doi.org/10.7554/elife.96459
Authors:
Revathi Balasubramanian
Krishnakumar Kizhatil
Taibo Li
Nicholas Tolman
Aakriti Bhandari
Graham Clark
Violet Bupp-Chickering
Ruth A. Kelly
Sally Zhou
John Peregrin
Marina Simón
Christa Montgomery
W. Daniel Stamer
Jiang Qian
Simon W. M. John
Affiliated Authors:
Revathi Balasubramanian
Nicholas Tolman
Aakriti Bhandari
Violet Bupp-Chickering
Sally Zhou
John Peregrin
Marina Simón
Christa Montgomery
Simon W. M. John
Columbia Affiliation:
Subjects:
Endothelial Cells (MeSH)
Gene Expression Profiling (MeSH)
Mice, Inbred C57BL (MeSH)
Lymphangiogenesis in Cancer Metastasis and Disease (OpenAlex Topic)
Molecular Characterization of Colorectal Cancer (OpenAlex Topic)
Biology and Pathology of Keratins and Related Disorders (OpenAlex Topic)
Author Keywords:
cell biology
glaucoma anterior segment
mouse
schlemm's canal
single cell transcriptomics
trabecular meshwork
elink
Publication Type:
Article
Unique ID:
10.7554/elife.96459
PMID:
39422453
DOI:
10.7554/elife.96459
Journal:
eLife
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
View PubMed Record
View Scopus Record

Record Created: