P30CA054174

NIH – National Cancer Institute

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Promotion of DNA end resection by BRCA1-BARD1 in homologous recombination

Salunkhe, S., Daley, J. M., Kaur, H., Tomimatsu, N., Xue, C., Raina, V. B., Jasper, A. M., Rogers, C. M., Li, W., Zhou, S., Mojidra, R., Kwon, Y., Fang, Q., Ji, J.-H., Badamchi Shabestari, A., Fitzgerald, O., Dinh, H., Mukherjee, B., Habib, A. A., … Sung, P. (2024). Promotion of DNA end resection by BRCA1–BARD1 in homologous recombination. Nature, 634(8033), 482–491. https://doi.org/10.1038/s41586-024-07910-2
Authors:
Sameer Salunkhe
James M Daley
Hardeep Kaur
Nozomi Tomimatsu
Chaoyou Xue
Vivek B Raina
Angela M Jasper
Cody M Rogers
Wenjing Li
Shuo Zhou
Rahul Mojidra
Youngho Kwon
Qingming Fang
Jae-Hoon Ji
Aida Badamchi Shabestari
O'Taveon Fitzgerald
Hoang Dinh
Bipasha Mukherjee
Amyn A Habib
Robert Hromas
Alexander V Mazin
Elizabeth V Wasmuth
Shaun K Olsen
David S Libich
Daohong Zhou
Weixing Zhao
Eric C Greene
Sandeep Burma
Patrick Sung
Affiliated Authors:
Chaoyou Xue
Vivek B Raina
Eric C Greene
Columbia Affiliation:
Subjects:
BRCA1 Protein (MeSH)
DNA Breaks, Double-Stranded (MeSH)
Exodeoxyribonucleases (MeSH)
Homologous Recombination (MeSH)
RecQ Helicases (MeSH)
Tumor Suppressor Proteins (MeSH)
Ubiquitin-Protein Ligases (MeSH)
Grants:
R01CA236606 (NIH – National Cancer Institute)
F30CA278370 (NIH – National Cancer Institute)
R01CA244212 (NIH – National Cancer Institute)
P30CA054174 (NIH – National Cancer Institute)
R35CA241801 (NIH – National Cancer Institute)
R01CA168635 (NIH – National Cancer Institute)
R01CA246807 (NIH – National Cancer Institute)
R01CA139429 (NIH – National Cancer Institute)
R01CA221858 (NIH – National Cancer Institute)
R50CA265315 (NIH – National Cancer Institute)
R01CA219836 (NIH – National Cancer Institute)
R01ES007061 (NIH – National Institute of Environmental Health Sciences)
R35GM118026 (NIH – National Institute of General Medical Sciences)
R01GM136717 (NIH – National Institute of General Medical Sciences)
R01GM141091 (NIH – National Institute of General Medical Sciences)
R00GM140264 (NIH – National Institute of General Medical Sciences)
R01GM140127 (NIH – National Institute of General Medical Sciences)
R01GM128731 (NIH – National Institute of General Medical Sciences)
R01GM115568 (NIH – National Institute of General Medical Sciences)
T32GM145432 (NIH – National Institute of General Medical Sciences)
R01NS119225 (NIH – National Institute of Neurological Disorders and Stroke)
S10OD030432 (NIH – Office of the Director, National Institutes of Health)
Publication Type:
Article
Unique ID:
10.1038/s41586-024-07910-2
PMID:
39261729
DOI:
10.1038/s41586-024-07910-2
Journal:
Nature
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Clinical characteristics, racial inequities, and outcomes in patients with breast cancer and COVID-19: A COVID-19 and cancer consortium (CCC19) cohort study

Nagaraj, G., Vinayak, S., Khaki, A. R., Sun, T., Kuderer, N. M., Aboulafia, D. M., Acoba, J. D., Awosika, J., Bakouny, Z., Balmaceda, N. B., Bao, T., Bashir, B., Berg, S., Bilen, M. A., Bindal, P., Blau, S., Bodin, B. E., Borno, H. T., … Castellano, C. (2023). Clinical characteristics, racial inequities, and outcomes in patients with breast cancer and COVID-19: A COVID-19 and cancer consortium (CCC19) cohort study. ELife, 12. CLOCKSS. https://doi.org/10.7554/elife.82618
Authors:
Gayathri Nagaraj
Shaveta Vinayak
Ali Raza Khaki
Tianyi Sun
Nicole M. Kuderer
David M. Aboulafia
Jared D. Acoba
Joy Awosika
Ziad Bakouny
Nicole Baranda Balmaceda
Ting Bao
Babar Bashir
Stephanie Berg
Mehmet Asım Bilen
Poorva Bindal
Sibel Blau
Brianne E. Bodin
Hala T. Borno
Cecilia A. Castellano
Horyun Choi
John F. Deeken
Aakash Desai
Natasha Edwin
Lawrence E. Feldman
Daniel B. Flora
Christopher R. Friese
Matthew D. Galsky
Cyndi J Gonzalez
Petros Grivas
Shilpa Gupta
Marcy Haynam
Hannah Heilman
Dawn L. Hershman
Clara Hwang
Chinmay Jani
Sachin R. Jhawar
Monika Joshi
Virginia Kaklamani
Elizabeth J. Klein
Natalie Knox
Vadim S. Koshkin
Amit Kulkarni
Daniel H. Kwon
Chris Labaki
Philip E. Lammers
Kate Lathrop
Mark A. Lewis
Xuanyi Li
Gilberto Lopes
Gary H. Lyman
Della Makower
Abdul-Hai Mansoor
Merry Jennifer Markham
Sandeep H. Mashru
Rana R. McKay
Ian Messing
Vasil Mico
Rajani Nadkarni
Swathi Namburi
Ruby H.N. Nguyen
Taylor K. Nonato
Tracey L. O’Connor
Orestis A. Panagiotou
Kyu Park
Jaymin Patel
Kanishka G. Patel
Jeffrey Peppercorn
Hyma Polimera
Matthew Puc
Yuan James Rao
Pedram Razavi
Sonya Reid
Jonathan W. Riess
Donna R. Rivera
Mark E. Robson
Suzanne J. Rose
Atlantis Dawn Russ
Lidia Schapira
Pankil Shah
M Kelly Shanahan
Lauren C. Shapiro
Melissa Smits
Daniel G. Stover
Mitrianna Streckfuss
Lisa Tachiki
Michael A Thompson
Sara M. Tolaney
Lisa B. Weissmann
Grace Wilson
Michael Wotman
Elizabeth Wulff‐Burchfield
Sanjay Mishra
Benjamin French
Jeremy L. Warner
Maryam B. Lustberg
Melissa K. Accordino
Dimpy P. Shah
Affiliated Authors:
Brianne E. Bodin
Dawn L. Hershman
Melissa K. Accordino
Columbia Affiliation:
Subjects:
COVID-19 (MeSH)
Breast Neoplasms (MeSH)
Impact of COVID-19 on Cancer Patients and Care (OpenAlex Topic)
Global Cancer Incidence and Mortality Patterns (OpenAlex Topic)
Economic Burden of Cancer Treatment (OpenAlex Topic)
Author Keywords:
covid-19
sars-cov-2
breast cancer
epidemiology
global health
human
oncology
pandemic
racial inequities
Grants:
P30CA068485 (NIH – National Cancer Institute)
P30CA054174 (NIH – National Cancer Institute)
P30CA023100 (NIH – National Cancer Institute)
P30CA046592 (NIH – National Cancer Institute)
P30CA008748 (NIH – National Cancer Institute)
UL1TR000445 (NIH – National Center for Advancing Translational Sciences)
KL2TR002646 (NIH – National Center for Advancing Translational Sciences)
Publication Type:
Article
Unique ID:
10.7554/elife.82618
PMID:
37846664
DOI:
10.7554/elife.82618
Journal:
eLife
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
View PubMed Record

Record Created:

Structural insights into BCDX2 complex function in homologous recombination

Rawal, Y., Jia, L., Meir, A., Zhou, S., Kaur, H., Ruben, E. A., Kwon, Y., Bernstein, K. A., Jasin, M., Taylor, A. B., Burma, S., Hromas, R., Mazin, A. V., Zhao, W., Zhou, D., Wasmuth, E. V., Greene, E. C., Sung, P., & Olsen, S. K. (2023). Structural insights into BCDX2 complex function in homologous recombination. Nature, 619(7970), 640–649. https://doi.org/10.1038/s41586-023-06219-w
Authors:
Yashpal Rawal
Lijia Jia
Aviv Meir
Shuo Zhou
Hardeep Kaur
Eliza A Ruben
Youngho Kwon
Kara A Bernstein
Maria Jasin
Alexander B Taylor
Sandeep Burma
Robert Hromas
Alexander V Mazin
Weixing Zhao
Daohong Zhou
Elizabeth V Wasmuth
Eric C Greene
Patrick Sung
Shaun K Olsen
Affiliated Authors:
Aviv Meir
Eric C Greene
Columbia Affiliation:
Subjects:
DNA-Binding Proteins (MeSH)
Homologous Recombination (MeSH)
Multiprotein Complexes (MeSH)
Grants:
P30CA008748 (NIH – National Cancer Institute)
R35CA241801 (NIH – National Cancer Institute)
R01CA237286 (NIH – National Cancer Institute)
P01CA092584 (NIH – National Cancer Institute)
R01CA258381 (NIH – National Cancer Institute)
R01CA246807 (NIH – National Cancer Institute)
R01CA221858 (NIH – National Cancer Institute)
R01CA188347 (NIH – National Cancer Institute)
R50CA265315 (NIH – National Cancer Institute)
R01CA168635 (NIH – National Cancer Institute)
R01CA139429 (NIH – National Cancer Institute)
P30CA054174 (NIH – National Cancer Institute)
R01ES031796 (NIH – National Institute of Environmental Health Sciences)
R01ES030335 (NIH – National Institute of Environmental Health Sciences)
P30ES013508 (NIH – National Institute of Environmental Health Sciences)
R01ES007061 (NIH – National Institute of Environmental Health Sciences)
R01GM128731 (NIH – National Institute of General Medical Sciences)
R01GM115568 (NIH – National Institute of General Medical Sciences)
R01GM136717 (NIH – National Institute of General Medical Sciences)
R35GM118026 (NIH – National Institute of General Medical Sciences)
R00GM140264 (NIH – National Institute of General Medical Sciences)
R01GM141091 (NIH – National Institute of General Medical Sciences)
Publication Type:
Article
Unique ID:
10.1038/s41586-023-06219-w
PMID:
37344589
DOI:
10.1038/s41586-023-06219-w
Journal:
Nature
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record

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Interplay of Immunosuppression and Immunotherapy Among Patients With Cancer and COVID-19

Bakouny, Z., Labaki, C., Grover, P., Awosika, J., Gulati, S., Hsu, C.-Y., Alimohamed, S. I., Bashir, B., Berg, S., Bilen, M. A., Bowles, D., Castellano, C., Desai, A., Elkrief, A., Eton, O. E., Fecher, L. A., Flora, D., Galsky, M. D., Gatti-Mays, M. E., … Stratton, C. (2023). Interplay of Immunosuppression and Immunotherapy Among Patients With Cancer and COVID-19. JAMA Oncology, 9(1), 128. https://doi.org/10.1001/jamaoncol.2022.5357
Authors:
Ziad Bakouny
Chris Labaki
Punita Grover
Joy Awosika
Shuchi Gulati
Chih–Yuan Hsu
Saif Alimohamed
Babar Bashir
Stephanie Berg
Mehmet Asım Bilen
Daniel W. Bowles
Cecilia A. Castellano
Aakash Desai
Arielle Elkrief
Omar Eton
Leslie A. Fecher
Daniel B. Flora
Matthew D. Galsky
Margaret E. Gatti‐Mays
Alicia Gesenhues
Michael Glover
Dharmesh Gopalakrishnan
Shilpa Gupta
Þorvarður R. Hálfdánarson
Brandon Hayes‐Lattin
Mohamed Hendawi
Emily Hsu
Clara Hwang
Roman Jandarov
Chinmay Jani
Douglas B. Johnson
Monika Joshi
Hina Khan
Shaheer Khan
Natalie Knox
Vadim S. Koshkin
Amit Kulkarni
Daniel H. Kwon
Sara Matar
Rana R. McKay
Sanjay Mishra
Feras A. Moria
Amanda Nizam
Nora L. Nock
Taylor K. Nonato
Justin Panasci
Lauren Pomerantz
Andrew J. Portuguese
Destie Provenzano
Matthew Puc
Yuan James Rao
Terence D. Rhodes
Gregory J. Riely
Jacob Ripp
Andrea Verghese Rivera
Erika Ruiz‐García
Andrew Schmidt
Adam J. Schoenfeld
Gary K. Schwartz
Sumit Shah
Justin Shaya
Suki Subbiah
Lisa Tachiki
Matthew D. Tucker
Melissa Valdés-Reyes
Lisa B. Weissmann
Michael Wotman
Elizabeth Wulff‐Burchfield
Zhuoer Xie
Yuanchu James Yang
Michael A. Thompson
Dimpy P. Shah
Jeremy L. Warner
Yu Shyr
Toni K. Choueiri
Trisha M. Wise‐Draper
Ariel Fromowitz
Rikin Gandhi
Benjamin A. Gartrell
Sanjay Goel
Balázs Halmos
Della Makower
Darciann O' Sullivan
Nitin Ohri
Mary Portes
Lauren C. Shapiro
Aditi Shastri
R. Alejandro Sica
Amit Verma
Omar H. Butt
Jian L. Campian
Mark A. Fiala
Jeffrey P. Henderson
Ryan Monahan
Keith Stockerl‐Goldstein
Alice Y. Zhou
Jacob D. Bitran
Sigrun Hallmeyer
Daniel Mundt
Sasirekha Pandravada
Affiliated Authors:
Shaheer Khan
Gary K. Schwartz
Columbia Affiliation:
Subjects:
COVID-19 (MeSH)
Neoplasms (MeSH)
Impact of COVID-19 on Cancer Patients and Care (OpenAlex Topic)
Coronavirus Disease 2019 (OpenAlex Topic)
Airborne Transmission of Respiratory Viruses (OpenAlex Topic)
Grants:
P30CA054174 (NIH – National Cancer Institute)
P30CA008748 (NIH – National Cancer Institute)
K12CA090625 (NIH – National Cancer Institute)
P30CA016058 (NIH – National Cancer Institute)
T32CA009515 (NIH – National Cancer Institute)
P30CA068485 (NIH – National Cancer Institute)
UL1TR000445 (NIH – National Center for Advancing Translational Sciences)
KL2TR001426 (NIH – National Center for Advancing Translational Sciences)
UL1TR001425 (NIH – National Center for Advancing Translational Sciences)
K23AG073534 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1001/jamaoncol.2022.5357
PMID:
36326731
DOI:
10.1001/jamaoncol.2022.5357
Journal:
JAMA Oncology
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
View Web of Science Record
View PubMed Record

Record Created:

Efficacy and safety of avapritinib in advanced systemic mastocytosis: interim analysis of the phase 2 PATHFINDER trial

Gotlib, J., Reiter, A., Radia, D. H., Deininger, M. W., George, T. I., Panse, J., Vannucchi, A. M., Platzbecker, U., Alvarez-Twose, I., Mital, A., Hermine, O., Dybedal, I., Hexner, E. O., Hicks, L. K., Span, L., Mesa, R., Bose, P., Pettit, K. M., Heaney, M. L., … DeAngelo, D. J. (2021). Efficacy and safety of avapritinib in advanced systemic mastocytosis: interim analysis of the phase 2 PATHFINDER trial. Nature Medicine, 27(12), 2192–2199. https://doi.org/10.1038/s41591-021-01539-8
Authors:
Jason Gotlib
Andreas Reiter
Deepti H Radia
Michael W Deininger
Tracy I George
Jens Panse
Alessandro M Vannucchi
Uwe Platzbecker
Iván Alvarez-Twose
Andrzej Mital
Olivier Hermine
Ingunn Dybedal
Elizabeth O Hexner
Lisa K Hicks
Lambert Span
Ruben Mesa
Prithviraj Bose
Kristen M Pettit
Mark L Heaney
Stephen T Oh
Jayita Sen
Hui-Min Lin
Brenton G Mar
Daniel J DeAngelo
Affiliated Authors:
Mark L Heaney
Subjects:
Role of Mast Cells in Immunoregulation and Disease (OpenAlex Topic)
Hypereosinophilic Syndrome and Related Disorders (OpenAlex Topic)
Pathogenesis and Treatment of Pemphigoid Diseases (OpenAlex Topic)
Mastocytosis, Systemic (MeSH)
Pyrazoles (MeSH)
Pyrroles (MeSH)
Triazines (MeSH)
Grants:
P01CA214278 (NIH – National Cancer Institute)
P30CA016672 (NIH – National Cancer Institute)
P30CA054174 (NIH – National Cancer Institute)
UE5CA246744 (NIH – National Cancer Institute)
UL1TR001878 (NIH – National Center for Advancing Translational Sciences)
R01HL148014 (NIH – National Heart, Lung, and Blood Institute)
Publication Type:
Article
Unique ID:
10.1038/s41591-021-01539-8
PMID:
34873345
DOI:
10.1038/s41591-021-01539-8
Journal:
Nature Medicine
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View OpenAlex Record
View Scopus Record
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Record Created:

Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer Consortium

Grivas, P., Khaki, A. R., Wise-Draper, T. M., French, B., Hennessy, C., Hsu, C.-Y., Shyr, Y., Li, X., Choueiri, T. K., Painter, C. A., Peters, S., Rini, B. I., Thompson, M. A., Mishra, S., Rivera, D. R., Acoba, J. D., Abidi, M. Z., Bakouny, Z., Bashir, B., … Lopes, GdL. (2021). Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer Consortium. Annals of Oncology, 32(6), 787–800. https://doi.org/10.1016/j.annonc.2021.02.024
Authors:
P. Grivas
A.R. Khaki
T.M. Wise-Draper
B. French
C. Hennessy
C.-Y. Hsu
Y. Shyr
X. Li
T.K. Choueiri
C.A. Painter
S. Peters
B.I. Rini
M.A. Thompson
S. Mishra
D.R. Rivera
J.D. Acoba
M.Z. Abidi
Z. Bakouny
B. Bashir
T. Bekaii-Saab
S. Berg
E.H. Bernicker
M.A. Bilen
P. Bindal
R. Bishnoi
N. Bouganim
D.W. Bowles
A. Cabal
P.F. Caimi
D.D. Chism
J. Crowell
C. Curran
A. Desai
B. Dixon
D.B. Doroshow
E.B. Durbin
A. Elkrief
D. Farmakiotis
A. Fazio
L.A. Fecher
D.B. Flora
C.R. Friese
J. Fu
S.M. Gadgeel
M.D. Galsky
D.M. Gill
M.J. Glover
S. Goyal
P. Grover
S. Gulati
S. Gupta
S. Halabi
T.R. Halfdanarson
B. Halmos
D.J. Hausrath
J.E. Hawley
E. Hsu
M. Huynh-Le
C. Hwang
C. Jani
A. Jayaraj
D.B. Johnson
A. Kasi
H. Khan
V.S. Koshkin
N.M. Kuderer
D.H. Kwon
P.E. Lammers
A. Li
A. Loaiza-Bonilla
C.A. Low
M.B. Lustberg
G.H. Lyman
R.R. McKay
C. McNair
H. Menon
R.A. Mesa
V. Mico
D. Mundt
G. Nagaraj
E.S. Nakasone
J. Nakayama
A. Nizam
N.L. Nock
C. Park
J.M. Patel
K.G. Patel
P. Peddi
N.A. Pennell
A.J. Piper-Vallillo
M. Puc
D. Ravindranathan
M.E. Reeves
D.Y. Reuben
L. Rosenstein
R.P. Rosovsky
S.M. Rubinstein
M. Salazar
A.L. Schmidt
G.K. Schwartz
M.R. Shah
S.A. Shah
C. Shah
J.A. Shaya
S.R.K. Singh
M. Smits
K.E. Stockerl-Goldstein
D.G. Stover
M. Streckfuss
S. Subbiah
L. Tachiki
E. Tadesse
A. Thakkar
M.D. Tucker
A.K. Verma
D.C. Vinh
M. Weiss
J.T. Wu
E. Wulff-Burchfield
Z. Xie
P.P. Yu
T. Zhang
A.Y. Zhou
H. Zhu
L. Zubiri
D.P. Shah
J.L. Warner
GdL. Lopes
Affiliated Authors:
J.E. Hawley
G.K. Schwartz
Columbia Affiliation:
Subjects:
COVID-19 (MeSH)
Neoplasms (MeSH)
Impact of COVID-19 on Cancer Patients and Care (OpenAlex Topic)
Coronavirus Disease 2019 (OpenAlex Topic)
Strategies to Reduce Low-Value Health Care Services (OpenAlex Topic)
Author Keywords:
sars-cov2
anticancer therapy
cancer
laboratory measurements
neoplasm
outcomes
Grants:
P30CA013330 (NIH – National Cancer Institute)
T32CA009515 (NIH – National Cancer Institute)
T32CA236621 (NIH – National Cancer Institute)
P30CA015704 (NIH – National Cancer Institute)
P30CA196521 (NIH – National Cancer Institute)
P30CA168524 (NIH – National Cancer Institute)
P30CA240139 (NIH – National Cancer Institute)
P30CA046592 (NIH – National Cancer Institute)
UG1CA189974 (NIH – National Cancer Institute)
P30CA016058 (NIH – National Cancer Institute)
UG1CA189859 (NIH – National Cancer Institute)
P30CA177558 (NIH – National Cancer Institute)
UG1CA190140 (NIH – National Cancer Institute)
P30CA013696 (NIH – National Cancer Institute)
P30CA068485 (NIH – National Cancer Institute)
U01CA231840 (NIH – National Cancer Institute)
P30CA056036 (NIH – National Cancer Institute)
P30CA023100 (NIH – National Cancer Institute)
P30CA054174 (NIH – National Cancer Institute)
P30CA046934 (NIH – National Cancer Institute)
UL1TR000445 (NIH – National Center for Advancing Translational Sciences)
UL1TR001873 (NIH – National Center for Advancing Translational Sciences)
UL1TR001425 (NIH – National Center for Advancing Translational Sciences)
Publication Type:
Article
Unique ID:
10.1016/j.annonc.2021.02.024
PMID:
33746047
DOI:
10.1016/j.annonc.2021.02.024
Journal:
Annals of Oncology
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View Web of Science Record
View PubMed Record
View OpenAlex Record

Record Created:

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