Plasmodium

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Siqueira-Neto, J. L., Wicht, K. J., Chibale, K., Burrows, J. N., Fidock, D. A., & Winzeler, E. A. (2023). Antimalarial drug discovery: progress and approaches. Nature Reviews Drug Discovery, 22(10), 807–826. https://doi.org/10.1038/s41573-023-00772-9
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Deni, I., Stokes, B. H., Ward, K. E., Fairhurst, K. J., Pasaje, C. F. A., Yeo, T., Akbar, S., Park, H., Muir, R., Bick, D. S., Zhan, W., Zhang, H., Liu, Y. J., Ng, C. L., Kirkman, L. A., Almaliti, J., Gould, A. E., Duffey, M., O’Donoghue, A. J., … Fidock, D. A. (2023). Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome. Cell Chemical Biology, 30(5), 470-485.e6. https://doi.org/10.1016/j.chembiol.2023.03.002
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Arendse, L. B., Murithi, J. M., Qahash, T., Pasaje, C. F. A., Godoy, L. C., Dey, S., Gibhard, L., Ghidelli-Disse, S., Drewes, G., Bantscheff, M., Lafuente-Monasterio, M. J., Fienberg, S., Wambua, L., Gachuhi, S., Coertzen, D., van der Watt, M., Reader, J., Aswat, A. S., Erlank, E., … Chibale, K. (2022). The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages. Science Translational Medicine, 14(667). https://doi.org/10.1126/scitranslmed.abo7219
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Forte, B., Ottilie, S., Plater, A., Campo, B., Dechering, K. J., Gamo, F. J., Goldberg, D. E., Istvan, E. S., Lee, M., Lukens, A. K., McNamara, C. W., Niles, J. C., Okombo, J., Pasaje, C. F. A., Siegel, M. G., Wirth, D., Wyllie, S., Fidock, D. A., Baragaña, B., … Gilbert, I. H. (2021). Prioritization of Molecular Targets for Antimalarial Drug Discovery. ACS Infectious Diseases, 7(10), 2764–2776. https://doi.org/10.1021/acsinfecdis.1c00322
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