Peroxisome Proliferator-Activated Receptors

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Plumber, S. A., Tate, T., Al-Ahmadie, H., Chen, X., Choi, W., Basar, M., Lu, C., Viny, A., Batourina, E., Li, J., Gretarsson, K., Alija, B., Molotkov, A., Wiessner, G., Lee, B. H. L., McKiernan, J., McConkey, D. J., Dinney, C., Czerniak, B., & Mendelsohn, C. L. (2024). Rosiglitazone and trametinib exhibit potent anti-tumor activity in a mouse model of muscle invasive bladder cancer. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-50678-2
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Yarchoan, M., Powderly, J. D., Bastos, B. R., Karasic, T. B., Crysler, O. V., Munster, P. N., McKean, M. A., Emens, L. A., Saenger, Y. M., Ged, Y., Stagg, R., Smith, S., Whiting, C. C., Moon, A., Prasit, P., Jenkins, Y., Standifer, N., Dubensky, T. W., Whiting, S. H., & Ulahannan, S. V. (2024). First-in-human Phase I Trial of TPST-1120, an Inhibitor of PPARα, as Monotherapy or in Combination with Nivolumab, in Patients with Advanced Solid Tumors. Cancer Research Communications, 4(4), 1100–1110. https://doi.org/10.1158/2767-9764.crc-24-0082
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Kaiyrzhanov, R., Rad, A., Lin, S.-J., Bertoli-Avella, A., Kallemeijn, W. W., Godwin, A., Zaki, M. S., Huang, K., Lau, T., Petree, C., Efthymiou, S., Karimiani, E. G., Hempel, M., Normand, E. A., Rudnik-Schöneborn, S., Schatz, U. A., Baggelaar, M. P., Ilyas, M., Sultan, T., … Maroofian, R. (2023). Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders. Brain, 147(4), 1436–1456. https://doi.org/10.1093/brain/awad380
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Pian, X., Tang, Y., Sun, Y., Sheng, Y., Yan, S., Yuan, H., Sun, Y., Cui, J., & Li, Y. (2024). Danggui Shaoyao powder improves hepatic lipid metabolism in atherosclerosis mice via PPARγ-LXRα-ABCA1 pathway regulation. Journal of Traditional Chinese Medical Sciences, 11(2), 199–206. https://doi.org/10.1016/j.jtcms.2024.03.010
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Liu, B., Xie, D., Huang, X., Jin, S., Dai, Y., Sun, X., Li, D., Bennett, A. M., Diano, S., & Huang, Y. (2024). Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α. Diabetologia, 67(4), 724–737. https://doi.org/10.1007/s00125-023-06073-5
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Yuan, M., Mahmud, I., Katsushima, K., Joshi, K., Saulnier, O., Pokhrel, R., Lee, B., Liyanage, W., Kunhiraman, H., Stapleton, S., Gonzalez-Gomez, I., Kannan, R. M., Eisemann, T., Kolanthai, E., Seal, S., Garrett, T. J., Abbasi, S., Bockley, K., Hanes, J., … Perera, R. J. (2023). miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4. Acta Neuropathologica Communications, 11(1). https://doi.org/10.1186/s40478-023-01684-w
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Bedoya-Guzmán, F. A., Pacheco-Herrero, M., Salomon-Cruz, I. D., Barrera-Sandoval, A. M., Gutierrez Vargas, J. A., Villamil-Ortiz, J. G., Villegas Lanau, C. A., Arias-Londoño, J. D., Area-Gomez, E., & Cardona Gomez, G. P. (2023). BACE1 and SCD1 are associated with neurodegeneration. Frontiers in Aging Neuroscience, 15. https://doi.org/10.3389/fnagi.2023.1194203
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Chen, F., Wang, X., Jang, S.-K., Quach, B. C., Weissenkampen, J. D., Khunsriraksakul, C., Yang, L., Sauteraud, R., Albert, C. M., Allred, N. D. D., Arnett, D. K., Ashley-Koch, A. E., Barnes, K. C., Barr, R. G., Becker, D. M., Bielak, L. F., Bis, J. C., Blangero, J., Boorgula, M. P., … Liu, D. J. (2023). Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing. Nature Genetics, 55(2), 291–300. https://doi.org/10.1038/s41588-022-01282-x
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Huang, P.-P., Zhu, W.-Q., Xiao, J.-M., Zhang, Y.-Q., Li, R., Yang, Y., Shen, L., Luo, F., Dai, W., Lian, P.-A., Tang, Y.-X., Ran, J.-L., & Huang, X.-S. (2022). Alterations in sorting and secretion of hepatic apoA5 induce hypertriglyceridemia due to short-term use of olanzapine. Frontiers in Pharmacology, 13. https://doi.org/10.3389/fphar.2022.935362
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Coon, B. G., Timalsina, S., Astone, M., Zhuang, Z. W., Fang, J., Han, J., Themen, J., Chung, M., Yang-Klingler, Y. J., Jain, M., Hirschi, K. K., Yamamato, A., Trudeau, L.-E., Santoro, M., & Schwartz, M. A. (2022). A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells. Journal of Cell Biology, 221(7). https://doi.org/10.1083/jcb.202109144
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