Lin, X., Gupta, D., Vaitsiankova, A., Bhandari, S. K., Leung, K. S. K., Menolfi, D., Lee, B. J., Russell, H. R., Gershik, S., Huang, X., Gu, W., McKinnon, P. J., Dantzer, F., Rothenberg, E., Tomkinson, A. E., & Zha, S. (2024). Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts. Molecular Cell, 84(20), 3916-3931.e7. https://doi.org/10.1016/j.molcel.2024.09.020

Hu, X., Kabir, M., Lin, Y., Xiong, Y., Parsons, R. E., Gu, W., & Jin, J. (2024). Design, Synthesis, and Evaluation of p53Y220C Acetylation Targeting Chimeras (AceTACs). Journal of Medicinal Chemistry, 67(16), 14633–14648. https://doi.org/10.1021/acs.jmedchem.4c01497

de Queiroz, R. M., Efe, G., Guzman, A., Hashimoto, N., Kawashima, Y., Tanaka, T., Rustgi, A. K., & Prives, C. (2024). Mdm2 requires Sprouty4 to regulate focal adhesion formation and metastasis independent of p53. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-51488-2

Efe, G., Rustgi, A. K., & Prives, C. (2024). p53 at the crossroads of tumor immunity. Nature Cancer, 5(7), 983–995. https://doi.org/10.1038/s43018-024-00796-z

Elvira-Blázquez, D., Fernández-Justel, J. M., Arcas, A., Statello, L., Goñi, E., González, J., Ricci, B., Zaccara, S., Raimondi, I., & Huarte, M. (2024). YTHDC1 m6A-dependent and m6A-independent functions converge to preserve the DNA damage response. The EMBO Journal, 43(16), 3494–3522. https://doi.org/10.1038/s44318-024-00153-x

Liu, Y., Su, Z., Tavana, O., & Gu, W. (2024). Understanding the complexity of p53 in a new era of tumor suppression. Cancer Cell, 42(6), 946–967. https://doi.org/10.1016/j.ccell.2024.04.009

Regunath, K., Fomin, V., Liu, Z., Wang, P., Hoque, M., Tian, B., Rabadan, R., & Prives, C. (2024). Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types. Molecular Cancer Research, 22(6), 555–571. https://doi.org/10.1158/1541-7786.mcr-23-0295

Yi, J., Tavana, O., Li, H., Wang, D., Baer, R. J., & Gu, W. (2023). Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-37617-3

Li, F., Chen, D., Sun, Q., Wu, J., Gan, Y., Leong, K. W., & Liang, X. (2023). MDM2‐Targeting Reassembly Peptide (TRAP) Nanoparticles for p53‐Based Cancer Therapy. Advanced Materials, 35(45). Portico. https://doi.org/10.1002/adma.202305164

Whelan, K., Dillon, M., Strickland, K. C., Pothuri, B., Bae-Jump, V., Borden, L. E., Thaker, P. H., Haight, P., Arend, R. C., Ko, E., Jackson, A. L., Corr, B. R., Ayoola-Adeola, M., Wright, J. D., Podwika, S., Smitherman, C., Thomas, S., Lightfoot, M., Newton, M., … Alvarez Secord, A. (2023). TP53 mutation and abnormal p53 expression in endometrial cancer: Associations with race and outcomes. Gynecologic Oncology, 178, 44–53. https://doi.org/10.1016/j.ygyno.2023.09.009

Girish, V., Lakhani, A. A., Thompson, S. L., Scaduto, C. M., Brown, L. M., Hagenson, R. A., Sausville, E. L., Mendelson, B. E., Kandikuppa, P. K., Lukow, D. A., Yuan, M. L., Stevens, E. C., Lee, S. N., Schukken, K. M., Akalu, S. M., Vasudevan, A., Zou, C., Salovska, B., Li, W., … Sheltzer, J. M. (2023). Oncogene-like addiction to aneuploidy in human cancers. Science, 381(6660). https://doi.org/10.1126/science.adg4521

Yang, X., Wang, Z., Zandkarimi, F., Liu, Y., Duan, S., Li, Z., Kon, N., Zhang, Z., Jiang, X., Stockwell, B. R., & Gu, W. (2023). Regulation of VKORC1L1 is critical for p53-mediated tumor suppression through vitamin K metabolism. Cell Metabolism, 35(8), 1474-1490.e8. https://doi.org/10.1016/j.cmet.2023.06.014

Kabir, M., Sun, N., Hu, X., Martin, T. C., Yi, J., Zhong, Y., Xiong, Y., Kaniskan, H. Ü., Gu, W., Parsons, R., & Jin, J. (2023). Acetylation Targeting Chimera Enables Acetylation of the Tumor Suppressor p53. Journal of the American Chemical Society, 145(27), 14932–14944. https://doi.org/10.1021/jacs.3c04640

Sun, X.-L., Chen, Z.-H., Guo, X., Wang, J., Ge, M., Wong, S. Z. H., Wang, T., Li, S., Yao, M., Johnston, L. A., & Wu, Q.-F. (2023). Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development. Developmental Cell, 58(9), 744-759.e11. https://doi.org/10.1016/j.devcel.2023.03.016

Ambrosini, G., Natale, C. A., Musi, E., Garyantes, T., & Schwartz, G. K. (2023). The GPER Agonist LNS8801 Induces Mitotic Arrest and Apoptosis in Uveal Melanoma Cells. Cancer Research Communications, 3(4), 540–547. https://doi.org/10.1158/2767-9764.crc-22-0399

Su, Z., Kon, N., Yi, J., Zhao, H., Zhang, W., Tang, Q., Li, H., Kobayashi, H., Li, Z., Duan, S., Liu, Y., Olive, K. P., Zhang, Z., Honig, B., Manfredi, J. J., Rustgi, A. K., & Gu, W. (2023). Specific regulation of BACH1 by the hotspot mutant p53R175H reveals a distinct gain-of-function mechanism. Nature Cancer, 4(4), 564–581. https://doi.org/10.1038/s43018-023-00532-z

Caspa Gokulan, R., Paulrasu, K., Azfar, J., El-Rifai, W., Que, J., Boutaud, O. G., Ban, Y., Gao, Z., Buitrago, M. G., Dikalov, S. I., & Zaika, A. I. (2023). Protein adduction causes non-mutational inhibition of p53 tumor suppressor. Cell Reports, 42(1), 112024. https://doi.org/10.1016/j.celrep.2023.112024

Liu, Y., & Gu, W. (2022). The complexity of p53-mediated metabolic regulation in tumor suppression. Seminars in Cancer Biology, 85, 4–32. https://doi.org/10.1016/j.semcancer.2021.03.010

Xia, Z., Kon, N., Gu, A. P., Tavana, O., & Gu, W. (2022). Deciphering the acetylation code of p53 in transcription regulation and tumor suppression. Oncogene, 41(22), 3039–3050. https://doi.org/10.1038/s41388-022-02331-9