Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia

Wang, Y., Spolitu, S., Zadroga, J. A., Sarecha, A. K., & Ozcan, L. (2022). Hepatocyte Rap1a contributes to obesity- and statin-associated hyperglycemia. Cell Reports, 40(8), 111259. https://doi.org/10.1016/j.celrep.2022.111259
Authors:
Yating Wang
Stefano Spolitu
John A. Zadroga
Amesh K. Sarecha
Lale Özcan
Affiliated Authors:
Yating Wang
Stefano Spolitu
John A. Zadroga
Amesh K. Sarecha
Lale Özcan
Columbia Affiliation:
Subjects:
Diabetes Mellitus, Type 2 (MeSH)
Glucose Intolerance (MeSH)
Hydroxymethylglutaryl-CoA Reductase Inhibitors (MeSH)
Hyperglycemia (MeSH)
Molecular Mechanisms of Ras Signaling Pathways (OpenAlex Topic)
Role of AMP-Activated Protein Kinase in Cellular Metabolism (OpenAlex Topic)
mTOR Signaling in Growth and Disease (OpenAlex Topic)
Author Keywords:
cp: metabolism
geranylgeranylation
gluconeogenesis
hepatic glucose production
hyperglycemia
obesity
rap1a
statins
type 2 diabetes
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Publication Type:
Article
Unique ID:
10.1016/j.celrep.2022.111259
PMID:
36001955
DOI:
10.1016/j.celrep.2022.111259
Journal:
Cell Reports
Publication Date:
Data Source:
OpenAlex
Source Link:
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