CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer

Filippone, M. G., Gaglio, D., Bonfanti, R., Tucci, F. A., Ceccacci, E., Pennisi, R., Bonanomi, M., Jodice, G., Tillhon, M., Montani, F., Bertalot, G., Freddi, S., Vecchi, M., Taglialatela, A., Romanenghi, M., Romeo, F., Bianco, N., Munzone, E., Sanguedolce, F., … Pece, S. (2022). CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-30375-8

Authors:

M.G. Filippone

D. Gaglio

R. Bonfanti

F.A. Tucci

E. Ceccacci

R. Pennisi

M. Bonanomi

G. Jodice

M. Tillhon

F. Montani

G. Bertalot