Genome sequence analyses identify novel risk loci for multiple system atrophy

Chia, R., Ray, A., Shah, Z., Ding, J., Ruffo, P., Fujita, M., Menon, V., Saez-Atienzar, S., Reho, P., Kaivola, K., Walton, R. L., Reynolds, R. H., Karra, R., Sait, S., Akcimen, F., Diez-Fairen, M., Alvarez, I., Fanciulli, A., Stefanova, N., … Scholz, S. W. (2024). Genome sequence analyses identify novel risk loci for multiple system atrophy. Neuron, 112(13), 2142-2156.e5. https://doi.org/10.1016/j.neuron.2024.04.002
Authors:
Ruth Chia
Anindita Ray
Zalak Shah
Jinhui Ding
Paola Ruffo
Masashi Fujita
Vilas Menon
Sara Saez-Atienzar
Paolo Reho
Karri Kaivola
Ronald L Walton
Regina H Reynolds
Ramita Karra
Shaimaa Sait
Fulya Akcimen
Monica Diez-Fairen
Ignacio Alvarez
Alessandra Fanciulli
Nadia Stefanova
Klaus Seppi
Susanne Duerr
Fabian Leys
Florian Krismer
Victoria Sidoroff
Alexander Zimprich
Walter Pirker
Olivier Rascol
Alexandra Foubert-Samier
Wassilios G Meissner
François Tison
Anne Pavy-Le Traon
Maria Teresa Pellecchia
Paolo Barone
Maria Claudia Russillo
Juan Marín-Lahoz
Jaime Kulisevsky
Soraya Torres
Pablo Mir
Maria Teresa Periñán
Christos Proukakis
Viorica Chelban
Lesley Wu
Yee Y Goh
Laura Parkkinen
Michele T Hu
Christopher Kobylecki
Jennifer A Saxon
Sara Rollinson
Emily Garland
Italo Biaggioni
Irene Litvan
Ileana Rubio
Roy N Alcalay
Kimberly T Kwei
Steven J Lubbe
Qinwen Mao
Margaret E Flanagan
Rudolph J Castellani
Vikram Khurana
Alain Ndayisaba
Andrea Calvo
Gabriele Mora
Antonio Canosa
Gianluca Floris
Ryan C Bohannan
Anni Moore
Lucy Norcliffe-Kaufmann
Jose-Alberto Palma
Horacio Kaufmann
Changyoun Kim
Michiyo Iba
Eliezer Masliah
Ted M Dawson
Liana S Rosenthal
Alexander Pantelyat
Marilyn S Albert
Olga Pletnikova
Juan C Troncoso
Jon Infante
Carmen Lage
Pascual Sánchez-Juan
Geidy E Serrano
Thomas G Beach
Pau Pastor
Huw R Morris
Diego Albani
Jordi Clarimon
Gregor K Wenning
John A Hardy
Mina Ryten
Eric Topol
Ali Torkamani
Adriano Chiò
David A Bennett
Philip L De Jager
Philip A Low
Wolfgang Singer
William P Cheshire
Zbigniew K Wszolek
Dennis W Dickson
Bryan J Traynor
J Raphael Gibbs
Clifton L Dalgard
Owen A Ross
Henry Houlden
Sonja W Scholz
Affiliated Authors:
Masashi Fujita
Vilas Menon
Roy N Alcalay
Kimberly T Kwei
Philip L De Jager
Columbia Affiliation:
Subjects:
Pathophysiology of Parkinson's Disease (OpenAlex Topic)
Nurr1/CoREST Pathway in Neuroprotection and Inflammation (OpenAlex Topic)
Neurodegeneration with Brain Iron Accumulation (OpenAlex Topic)
Multiple System Atrophy (MeSH)
Genome-Wide Association Study (MeSH)
Genetic Predisposition to Disease (MeSH)
Author Keywords:
colocalization
gene-burden analysis
genome-wide association study
gwas
msa
multiple system atrophy
pathway analysis
repeat expansion mapping
transcriptome-wide association study
twas
whole genome sequencing
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Publication Type:
Article
Unique ID:
10.1016/j.neuron.2024.04.002
PMID:
38701790
DOI:
10.1016/j.neuron.2024.04.002
Journal:
Neuron
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record
View OpenAlex Record

Record Created: