Division of Aging and Dementia
Zolnoori, M., Barrón, Y., Song, J., Noble, J., Burgdorf, J., Ryvicker, M., & Topaz, M. (2023). HomeADScreen: Developing Alzheimer’s disease and related dementia risk identification model in home healthcare. International Journal of Medical Informatics, 177, 105146. https://doi.org/10.1016/j.ijmedinf.2023.105146
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Columbia Affiliation
Saunders‐Pullman, R., Raymond, D., Ortega, R. A., Shalash, A., Gatto, E., Salari, M., Markgraf, M., Alcalay, R. N., Mascalzoni, D., Mencacci, N. E., Bonifati, V., Merello, M., Chung, S. J., Novakovic, I., Bardien, S., Pal, G., Hall, A., Hattori, N., Lynch, T., … Simuni, T. (2023). International Genetic Testing and Counseling Practices for Parkinson’s Disease. Movement Disorders, 38(8), 1527–1535. Portico. https://doi.org/10.1002/mds.29442
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Columbia Affiliation
McKay, N. S., Gordon, B. A., Hornbeck, R. C., Dincer, A., Flores, S., Keefe, S. J., Joseph-Mathurin, N., Jack, C. R., Koeppe, R., Millar, P. R., Ances, B. M., Chen, C. D., Daniels, A., Hobbs, D. A., Jackson, K., Koudelis, D., Massoumzadeh, P., McCullough, A., Nickels, M. L., … la Fougère, C. (2023). Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN). Nature Neuroscience, 26(8), 1449–1460. https://doi.org/10.1038/s41593-023-01359-8
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Columbia Affiliation
Agin‐Liebes, J., Hickman, R. A., Vonsattel, J. P., Faust, P. L., Flowers, X., Utkina Sosunova, I., Ntiri, J., Mayeux, R., Surface, M., Marder, K., Fahn, S., Przedborski, S., & Alcalay, R. N. (2023). Patterns of TDP‐43 Deposition in Brains with LRRK2 G2019S Mutations. Movement Disorders, 38(8), 1541–1545. Portico. https://doi.org/10.1002/mds.29449
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Columbia Affiliation
Pal, G., Cook, L., Schulze, J., Verbrugge, J., Alcalay, R. N., Merello, M., Sue, C. M., Bardien, S., Bonifati, V., Chung, S. J., Foroud, T., Gatto, E., Hall, A., Hattori, N., Lynch, T., Marder, K., Mascalzoni, D., Novaković, I., Thaler, A., … Klein, C. (2023). Genetic Testing in Parkinson’s Disease. Movement Disorders, 38(8), 1384–1396. Portico. https://doi.org/10.1002/mds.29500
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Columbia Affiliation
Brickman, A. M., Yeung, L.-K., Alschuler, D. M., Ottaviani, J. I., Kuhnle, G. G. C., Sloan, R. P., Luttmann-Gibson, H., Copeland, T., Schroeter, H., Sesso, H. D., Manson, J. E., Wall, M., & Small, S. A. (2023). Dietary flavanols restore hippocampal-dependent memory in older adults with lower diet quality and lower habitual flavanol consumption. Proceedings of the National Academy of Sciences, 120(23). https://doi.org/10.1073/pnas.2216932120
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Columbia Affiliation
Castaneda, I., Marder, K., Kashyap, S., & Rosenbaum, M. (2023). Clinical research resource support for off‐site research coordinators in intensive and specialty care units. Clinical and Translational Science, 16(6), 915–921. Portico. https://doi.org/10.1111/cts.13516
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Columbia Affiliation
Irving Institute for Clinical and Translational Research; Vagelos College of Physicians and Surgeons; Department of Neurology; Division of Aging and Dementia; Taub Institute for Research on Alzheimer’s Disease and the Aging Brain; Department of Pediatrics; Division of Neonatology and Perinatology; Division of Molecular Genetics
Narayan, C. K., Stein, C. M., Ake, J. M., Benavides, A., Huey, E. D., Goldman, J., Mejia, A., Chapman, S., Joyce, J. L., Stern, Y., Cosentino, S., & Sunderaraman, P. (2023). Financial Behaviors and Experiences of Financial Loss in those with Alzheimer’s disease and Frontotemporal Dementia: Preliminary findings from a survey. Alzheimer’s & Dementia, 19(S4). Portico. https://doi.org/10.1002/alz.066596
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Basavaraju, R., France, J., Sigmon, H. C., Girgis, R. R., Brucato, G., Lieberman, J. A., Small, S. A., & Provenzano, F. A. (2023). Increased parietal and occipital lobe gyrification predicts conversion to syndromal psychosis in a clinical high-risk cohort. Schizophrenia Research, 255, 246–255. https://doi.org/10.1016/j.schres.2023.03.027
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Columbia Affiliation
Gouveia Roque, C., Chung, K. M., McCurdy, E. P., Jagannathan, R., Randolph, L. K., Herline-Killian, K., Baleriola, J., & Hengst, U. (2023). CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer’s disease gene expression linked to neuropathology. Science Advances, 9(9). https://doi.org/10.1126/sciadv.add2671
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Columbia Affiliation
Idnay, B., Fang, Y., Dreisbach, C., Marder, K., Weng, C., & Schnall, R. (2023). Clinical research staff perceptions on a natural language processing-driven tool for eligibility prescreening: An iterative usability assessment. International Journal of Medical Informatics, 171, 104985. https://doi.org/10.1016/j.ijmedinf.2023.104985
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Columbia Affiliation
Vagelos College of Physicians and Surgeons; Department of Biomedical Informatics; Department of Neurology; Division of Aging and Dementia; Taub Institute for Research on Alzheimer’s Disease and the Aging Brain; School of Nursing; Heilbrunn Department of Population and Family Health; Mailman School of Public Health
Lauriola, V., Brickman, A. M., Sloan, R. P., & Small, S. A. (2023). Anatomical biology guides a search for nutrients for the aging brain. Molecular Aspects of Medicine, 89, 101154. https://doi.org/10.1016/j.mam.2022.101154
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Vollstedt, E., Schaake, S., Lohmann, K., Padmanabhan, S., Brice, A., Lesage, S., Tesson, C., Vidailhet, M., Wurster, I., Hentati, F., Mirelman, A., Giladi, N., Marder, K., Waters, C., Fahn, S., Kasten, M., Brüggemann, N., Borsche, M., … Foroud, T. (2023). Embracing Monogenic Parkinson’s Disease: The MJFF Global Genetic PD Cohort. Movement Disorders, 38(2), 286–303. Portico. https://doi.org/10.1002/mds.29288
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Columbia Affiliation
Jensen, A. M. G., Kitago, Y., Fazeli, E., Vægter, C. B., Small, S. A., Petsko, G. A., & Andersen, O. M. (2023). Dimerization of the Alzheimer’s disease pathogenic receptor SORLA regulates its association with retromer. Proceedings of the National Academy of Sciences, 120(4). https://doi.org/10.1073/pnas.2212180120
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Columbia Affiliation
Hickman, R. A., Faust, P. L., Marder, K., Yamamoto, A., & Vonsattel, J.-P. (2022). The distribution and density of Huntingtin inclusions across the Huntington disease neocortex: regional correlations with Huntingtin repeat expansion independent of pathologic grade. Acta Neuropathologica Communications, 10(1). https://doi.org/10.1186/s40478-022-01364-1
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Columbia Affiliation
Asadzadeh, J., Ruchti, E., Jiao, W., Limoni, G., MacLachlan, C., Small, S. A., Knott, G., Santa-Maria, I., & McCabe, B. D. (2022). Retromer deficiency in Tauopathy models enhances the truncation and toxicity of Tau. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-32683-5
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Columbia Affiliation
Cook, L., Schulze, J., Uhlmann, W. R., Verbrugge, J., Marder, K., Lee, A. J., Wang, Y., Alcalay, R. N., Nance, M., & Beck, J. C. (2022). Tools for communicating risk for Parkinson’s disease. Npj Parkinson’s Disease, 8(1). https://doi.org/10.1038/s41531-022-00432-6
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Columbia Affiliation
Constant, A. B., Basavaraju, R., France, J., Honig, L. S., Marder, K. S., & Provenzano, F. A. (2022). Longitudinal Patterns of Cortical Atrophy on MRI in Patients With Alzheimer Disease With and Without Lewy Body Pathology. Neurology, 99(17). https://doi.org/10.1212/wnl.0000000000200947
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Columbia Affiliation
Staffaroni, A. M., Quintana, M., Wendelberger, B., Heuer, H. W., Russell, L. L., Cobigo, Y., Wolf, A., Goh, S.-Y. M., Petrucelli, L., Gendron, T. F., Heller, C., Clark, A. L., Taylor, J. C., Wise, A., Ong, E., Forsberg, L., Brushaber, D., Rojas, J. C., VandeVrede, L., … Afonso, S. (2022). Temporal order of clinical and biomarker changes in familial frontotemporal dementia. Nature Medicine, 28(10), 2194–2206. https://doi.org/10.1038/s41591-022-01942-9
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Columbia Affiliation
Andersen, O. M., Bøgh, N., Landau, A. M., Pløen, G. G., Jensen, A. M. G., Monti, G., Ulhøi, B. P., Nyengaard, J. R., Jacobsen, K. R., Jørgensen, M. M., Holm, I. E., Kristensen, M. L., Alstrup, A. K. O., Hansen, E. S. S., Teunissen, C. E., Breidenbach, L., Droescher, M., Liu, Y., Pedersen, H. S., … Sørensen, C. B. (2022). A genetically modified minipig model for Alzheimer’s disease with SORL1 haploinsufficiency. Cell Reports Medicine, 3(9), 100740. https://doi.org/10.1016/j.xcrm.2022.100740
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Columbia Affiliation
Saunders-Pullman, R., Ortega, R. A., Wang, C., Raymond, D., Elango, S., Leaver, K., Urval, N., Katsnelson, V., Gerber, R., Swan, M., Shanker, V., Alcalay, R. N., Mirelman, A., Brumm, M. C., Mejia-Santana, H., Coffey, C. S., Marek, K., Ozelius, L. J., Giladi, N., … Bressman, S. B. (2022). Association of Olfactory Performance With Motor Decline and Age at Onset in People With Parkinson Disease and the LRRK2 G2019S Variant. Neurology, 99(8). https://doi.org/10.1212/wnl.0000000000200737
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Columbia Affiliation
Liu, C., Zhu, N., Sun, H., Zhang, J., Feng, X., Gjerswold-Selleck, S., Sikka, D., Zhu, X., Liu, X., Nuriel, T., Wei, H.-J., Wu, C.-C., Vaughan, J. T., Laine, A. F., Provenzano, F. A., Small, S. A., & Guo, J. (2022). Deep learning of MRI contrast enhancement for mapping cerebral blood volume from single-modal non-contrast scans of aging and Alzheimer’s disease brains. Frontiers in Aging Neuroscience, 14. https://doi.org/10.3389/fnagi.2022.923673
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Columbia Affiliation
Vagelos College of Physicians and Surgeons; Department of Pathology and Cell Biology; Taub Institute for Research on Alzheimer’s Disease and the Aging Brain; Department of Neurology; Division of Aging and Dementia; Department of Radiation Oncology; Department of Psychiatry; Zuckerman Mind, Brain, and Behavior Institute
Quinn, L., Playle, R., Drew, C. J. G., Taiyari, K., Williams-Thomas, R., Muratori, L. M., Hamana, K., Griffin, B. A., Kelson, M., Schubert, R., Friel, C., Morgan-Jones, P., Rosser, A., Busse, M., Montojo, T., Ruiz Idiago, J. M., Hershberg, J., Marder, K., Bordelon, Y., … Landwehrmeyer, B. (2022). Physical activity and exercise outcomes in Huntington’s disease (PACE-HD): results of a 12-month trial-within-cohort feasibility study of a physical activity intervention in people with Huntington’s disease. Parkinsonism & Related Disorders, 101, 75–89. https://doi.org/10.1016/j.parkreldis.2022.06.013
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Columbia Affiliation
Fang, Y., Idnay, B., Sun, Y., Liu, H., Chen, Z., Marder, K., Xu, H., Schnall, R., & Weng, C. (2022). Combining human and machine intelligence for clinical trial eligibility querying. Journal of the American Medical Informatics Association, 29(7), 1161–1171. https://doi.org/10.1093/jamia/ocac051
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Columbia Affiliation
Vagelos College of Physicians and Surgeons; Department of Biomedical Informatics; Department of Neurology; Division of Aging and Dementia; Taub Institute for Research on Alzheimer’s Disease and the Aging Brain; School of Nursing; Heilbrunn Department of Population and Family Health; Mailman School of Public Health
Ma, D. J., Le, H. A., Ye, Y., Laine, A. F., Lieberman, J. A., Rothman, D. L., Small, S. A., & Guo, J. (2021). MR spectroscopy frequency and phase correction using convolutional neural networks. Magnetic Resonance in Medicine, 87(4), 1700–1710. Portico. https://doi.org/10.1002/mrm.29103
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Columbia Affiliation
Barker, M. S., Gottesman, R. T., Manoochehri, M., Chapman, S., Appleby, B. S., Brushaber, D., Devick, K. L., Dickerson, B. C., Domoto-Reilly, K., Fields, J. A., Forsberg, L. K., Galasko, D. R., Ghoshal, N., Goldman, J., Graff-Radford, N. R., Grossman, M., Heuer, H. W., Hsiung, G.-Y., Knopman, D. S., … Weintraub, S. (2022). Proposed research criteria for prodromal behavioural variant frontotemporal dementia. Brain, 145(3), 1079–1097. https://doi.org/10.1093/brain/awab365
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Columbia Affiliation
Feng, X., Provenzano, F. A., & Small, S. A. (2022). A deep learning MRI approach outperforms other biomarkers of prodromal Alzheimer’s disease. Alzheimer’s Research & Therapy, 14(1). https://doi.org/10.1186/s13195-022-00985-x
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Columbia Affiliation
Pal, G., Mangone, G., Hill, E. J., Ouyang, B., Liu, Y., Lythe, V., Ehrlich, D., Saunders‐Pullman, R., Shanker, V., Bressman, S., Alcalay, R. N., Garcia, P., Marder, K. S., Aasly, J., Mouradian, M. M., Link, S., Rosenbaum, M., Anderson, S., Bernard, B., … Goetz, C. G. (2022). Parkinson Disease and Subthalamic Nucleus Deep Brain Stimulation: Cognitive Effects in GBA Mutation Carriers. Annals of Neurology, 91(3), 424–435. Portico. https://doi.org/10.1002/ana.26302
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Columbia Affiliation
Xu, Y., Surface, M., Chan, A. K., Halpern, J., Vanegas-Arroyave, N., Ford, B., Feeney, M. P., Kwei, K. T., Katus, L. E., Kuo, S.-H., Shah, H., Waters, C., Winfield, L. M., Beck, J. C., Przedborski, S., Fahn, S., & Alcalay, R. N. (2021). COVID-19 manifestations in people with Parkinson’s disease: a USA cohort. Journal of Neurology, 269(3), 1107–1113. https://doi.org/10.1007/s00415-021-10784-3
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Columbia Affiliation
Revah-Politi, A., Kushary, S. (Tina), Vena, N., May, H., Lippa, N., Bier, L., Goldman, J., Alkelai, A., Baugh, E., Zoghbi, A., Kayser, R., Goldstein, D., & Simpson, H. B. (2022). eP435: Issues in interpreting results in research genomic testing for common disorders: an example within an OCD cohort. Genetics in Medicine, 24(3), S272–S273. https://doi.org/10.1016/j.gim.2022.01.469
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Scott, G. D., Arnold, M. R., Beach, T. G., Gibbons, C. H., Kanthasamy, A. G., Lebovitz, R. M., Lemstra, A. W., Shaw, L. M., Teunissen, C. E., Zetterberg, H., Taylor, A. S., Graham, T. C., Boeve, B. F., Gomperts, S. N., Graff-Radford, N. R., Moussa, C., Poston, K. L., Rosenthal, L. S., Sabbagh, M. N., … Irwin, D. J. (2022). Fluid and Tissue Biomarkers of Lewy Body Dementia: Report of an LBDA Symposium. Frontiers in Neurology, 12. https://doi.org/10.3389/fneur.2021.805135
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Surface, M., Balwani, M., Waters, C., Haimovich, A., Gan‐Or, Z., Marder, K. S., Hsieh, T., Song, L., Padmanabhan, S., Hsieh, F., Merchant, K. M., & Alcalay, R. N. (2021). Plasma Glucosylsphingosine in GBA1 Mutation Carriers with and without Parkinson’s Disease. Movement Disorders, 37(2), 416–421. Portico. https://doi.org/10.1002/mds.28846
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Columbia Affiliation
Qureshi, Y. H., Berman, D. E., Marsh, S. E., Klein, R. L., Patel, V. M., Simoes, S., Kannan, S., Petsko, G. A., Stevens, B., & Small, S. A. (2022). The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer’s disease. Cell Reports, 38(3), 110262. https://doi.org/10.1016/j.celrep.2021.110262
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Columbia Affiliation
Hickman, R. A., Dewan, R., Cortes, E., Traynor, B. J., Marder, K., & Vonsattel, J.-P. (2021). Amyotrophic lateral sclerosis is over-represented in two Huntington’s disease brain bank cohorts: further evidence to support genetic pleiotropy of pathogenic HTT gene expansion. Acta Neuropathologica, 143(1), 105–108. https://doi.org/10.1007/s00401-021-02385-1
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Griguer, C. E., Oliva, C. R., Coffey, C. S., Cudkowicz, M. E., Conwit, R. A., Gudjonsdottir, A. L., Ecklund, D. J., Fedler, J. K., Neill-Hudson, T. M., Nabors, L. B., Benge, M., Hackney, J. R., Chase, M., Leonard, T. P., Patel, T., Colman, H., de la Fuente, M., Chaudhary, R., Marder, K., … Markert, J. (2021). Prospective biomarker study in newly diagnosed glioblastoma: Cyto-C clinical trial. Neuro-Oncology Advances, 4(1). https://doi.org/10.1093/noajnl/vdab186
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Basavaraju, R., Guo, J., Small, S. A., Lieberman, J. A., Girgis, R. R., & Provenzano, F. A. (2022). Hippocampal Glutamate and Positive Symptom Severity in Clinical High Risk for Psychosis. JAMA Psychiatry, 79(2), 178. https://doi.org/10.1001/jamapsychiatry.2021.3710
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Simoes, S., Guo, J., Buitrago, L., Qureshi, Y. H., Feng, X., Kothiya, M., Cortes, E., Patel, V., Kannan, S., Kim, Y. H., & Alzheimer's Disease Neuroimaging Initiative. (2021). Alzheimer's vulnerable brain region relies on a distinct retromer core dedicated to endosomal recycling. Cell Reports, 37(13), Article 110182. https://doi.org/10.1016/j.celrep.2021.110182
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Columbia Affiliation
Feeney, M. P., Xu, Y., Surface, M., Shah, H., Vanegas-Arroyave, N., Chan, A. K., Delaney, E., Przedborski, S., Beck, J. C., & Alcalay, R. N. (2021). The impact of COVID-19 and social distancing on people with Parkinson’s disease: a survey study. Npj Parkinson’s Disease, 7(1). https://doi.org/10.1038/s41531-020-00153-8
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McDonnell, E. I., Wang, Y., Goldman, J., & Marder, K. (2021). Age of Onset of Huntington’s Disease in Carriers of Reduced Penetrance Alleles. Movement Disorders, 36(12), 2958–2961. Portico. https://doi.org/10.1002/mds.28789
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Gurel, K., Serra, G. P., Allende, A. J. S., Brickman, A. M., Kreisl, W. C., & Gutierrez, J. (2021). Basilar artery dilatation relates to Alzheimer dementia, particularly among APOE4 non‐carriers. Alzheimer’s & Dementia, 17(S4). Portico. https://doi.org/10.1002/alz.054604
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Sloan, R. P., Wall, M., Yeung, L.-K., Feng, T., Feng, X., Provenzano, F., Schroeter, H., Lauriola, V., Brickman, A. M., & Small, S. A. (2021). Insights into the role of diet and dietary flavanols in cognitive aging: results of a randomized controlled trial. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-83370-2
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Singhania, A., Pham, J., Dhanwani, R., Frazier, A., Rezende Dutra, J., Marder, K. S., Phillips, E., Mallal, S., Amara, A. W., Standaert, D. G., Sulzer, D., Peters, B., Sette, A., & Lindestam Arlehamn, C. S. (2021). The TCR repertoire of α-synuclein-specific T cells in Parkinson’s disease is surprisingly diverse. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-020-79726-9
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Goldman, J. G., Boeve, B. F., Armstrong, M. J., Galasko, D. R., Galvin, J. E., Irwin, D. J., Leverenz, J. B., Marder, K., Abler, V., Biglan, K., Irizarry, M. C., Keller, B., Lai, R., Munsie, L., Belleville, M., Chaney, O., Richard, I., Taylor, A., & Graham, T. (2021). Lewy Body Dementia Association’s Industry Advisory Council: proceedings of the second annual meeting. Alzheimer’s Research & Therapy, 13(1). https://doi.org/10.1186/s13195-021-00868-7
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Bajorek, L. P., Kiekhofer, R., Hall, M., Taylor, J., Lucente, D. E., Brushaber, D., Appleby, B., Coppolla, G., Bordelon, Y. M., Botha, H., Dickerson, B. C., Dickson, D. W., Domoto‐Reilly, K., Fagan, A. M., Fields, J. A., Fong, J. C., Foroud, T. M., Forsberg, L. K., … Galasko, D. R. (2021). Demographic and psychosocial factors associated with the decision to learn mutation status in familial frontotemporal dementia and the impact of disclosure on mood. Alzheimer’s & Dementia, 17(S7). Portico. https://doi.org/10.1002/alz.050692
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Cook, L., Schulze, J., Verbrugge, J., Beck, J. C., Marder, K. S., Saunders-Pullman, R., Klein, C., Naito, A., Alcalay, R. N., Brice, A., Kumeh, A., West, A. B., Singleton, A., Naito, A., Schüle, B., Fiske, B., Gabbert, C., Klein, C., Marras, C., … Bonifati, V. (2021). The commercial genetic testing landscape for Parkinson’s disease. Parkinsonism & Related Disorders, 92, 107–111. https://doi.org/10.1016/j.parkreldis.2021.10.001
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