Global Burden of Leishmaniasis Incidence and Treatment

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Rawat, M., Padalino, G., Adika, E., Okombo, J., Yeo, T., Brancale, A., Fidock, D. A., Hoffmann, K. F., & Lee, M. C. S. (2025). Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity. PLOS Pathogens, 21(2), e1012216. https://doi.org/10.1371/journal.ppat.1012216
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Rosenthal, P. J., Asua, V., Bailey, J. A., Conrad, M. D., Ishengoma, D. S., Kamya, M. R., Rasmussen, C., Tadesse, F. G., Uwimana, A., & Fidock, D. A. (2024). The emergence of artemisinin partial resistance in Africa: how do we respond? The Lancet Infectious Diseases. https://doi.org/10.1016/s1473-3099(24)00141-5
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Kucharski, M., Wirjanata, G., Nayak, S., Boentoro, J., Dziekan, J. M., Assisi, C., van der Pluijm, R. W., Miotto, O., Mok, S., Dondorp, A. M., & Bozdech, Z. (2023). Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmodium falciparum. PLOS Pathogens, 19(1), e1011118. https://doi.org/10.1371/journal.ppat.1011118
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Lowe, M. A., Cardenas, A., Valentin, J.-P., Zhu, Z., Abendroth, J., Castro, J. L., Class, R., Delaunois, A., Fleurance, R., Gerets, H., Gryshkova, V., King, L., Lorimer, D. D., MacCoss, M., Rowley, J. H., Rosseels, M.-L., Royer, L., Taylor, R. D., Wong, M., … de Haro, T. (2022). Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362. Journal of Medicinal Chemistry, 65(20), 14121–14143. https://doi.org/10.1021/acs.jmedchem.2c01336
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