Ocular Cancer Research and Treatment

Displaying 1 - 27 of 27CSV
Haile, H., Upadhyayula, P. S., Karlovich, E., Sisti, M. B., Gill, B. J. A., & Donovan, L. E. (2025). Management of asynchronous multifocal adult glioblastoma with loss of BRAFV600E -mutant clonality: a case report. Acta Neuropathologica Communications, 13(1). https://doi.org/10.1186/s40478-024-01894-w
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Yeager, L. B., Li, C. Y., Bogolmony, D., Debelenko, L., & Marr, B. P. (2025). Vitreous Hemorrhage in Posterior Uveal Melanocytoma: Two Case Reports. Case Reports in Ophthalmological Medicine, 2025(1). Portico. https://doi.org/10.1155/crop/5126550
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Dimitriou, F., Orloff, M. M., Koch Hein, E. C., Cheng, P. F., Hughes, I. F., Simeone, E., Montazeri, K., Grover, P., Mehmi, I., Gerard, C. L., Gaudy-Marqueste, C., Grob, J.-J., Michielin, O., Hamid, O., Long, G. V., Sullivan, R., Kapiteijn, E., Johnson, D. B., Ascierto, P. A., … Dummer, R. (2025). Treatment sequence with tebentafusp and immune checkpoint inhibitors in patients with metastatic uveal melanoma and metastatic GNA11/GNAQ mutant melanocytic tumors. European Journal of Cancer, 214, 115161. https://doi.org/10.1016/j.ejca.2024.115161
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Yun, J. K., Ryu, Y. J., & Lee, Y. (2024). Case report: Squamous cell carcinoma in situ of the cornea without involvement of the limbus and conjunctiva. Frontiers in Medicine, 11. https://doi.org/10.3389/fmed.2024.1418228
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Connelly, C. F., Desai, N., Cimic, A., Gonzalez, A. A., & Baskota, S. U. (2024). A six‐year comprehensive review of eye cytology cases received at a tertiary level hospital. Diagnostic Cytopathology, 52(9), 511–518. Portico. https://doi.org/10.1002/dc.25341
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Gallitto, M., Pan, P. C., Chan, M. D., Milano, M. T., & Wang, T. J. C. (2024). The role of radiotherapy in immunotherapy strategies in the central nervous system. Neuro-Oncology, 26(Supplement_1), S66–S75. https://doi.org/10.1093/neuonc/noad184
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Ventin, M., Cattaneo, G., Jia, J., Arya, S., Maggs, L., Sun, Y., Boland, G. M., Jenkins, R. W., Ksander, B. R., Haq, R., Wang, X., Ryeom, S., Ferrone, C. R., & Ferrone, S. (2023). 317 B7-H3-targeted CAR T cell with an inducible caspase 9 suicide gene effectively eradicates uveal melanoma liver metastases. Regular and Young Investigator Award Abstracts. https://doi.org/10.1136/jitc-2023-sitc2023.0317
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Patel, S. P., Carvajal, R., Montazeri, K., Reddy, S., Lutzky, J., Khan, S. A., Chmielowski, B., Bhatia, S., Medina, T., Haymaker, C., Sheth, R., Kuban, J. D., Thornton, L., Wehrenberg-Klee, E., Novelli, P., Lucci, A., Sarli, V., Meas, S., Cox, B., … Davar, D. (2023). 1534 Clinical activity of SD-101 with immune checkpoint inhibition (ICI) in metastatic uveal melanoma liver metastasis (MUM-LM) from the PERIO-01 Phase 1 trial. Late-Breaking Abstracts. https://doi.org/10.1136/jitc-2023-sitc2023.1534
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Orloff, M., Watkins, C., Carvajal, R. D., Shoushtari, A. N., Sacco, J. J., Schlaak, M., Gama, J., & Butler, M. O. (2023). 1129P Effect of subsequent therapies including checkpoint inhibitors on overall survival in a phase III randomized trial of tebentafusp in first-line metastatic uveal melanoma: Long-term follow-up. Annals of Oncology, 34, S678. https://doi.org/10.1016/j.annonc.2023.09.2263
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Pavlick, A. C., Ariyan, C. E., Buchbinder, E. I., Davar, D., Gibney, G. T., Hamid, O., Hieken, T. J., Izar, B., Johnson, D. B., Kulkarni, R. P., Luke, J. J., Mitchell, T. C., Mooradian, M. J., Rubin, K. M., Salama, A. K., Shirai, K., Taube, J. M., Tawbi, H. A., Tolley, J. K., … Sullivan, R. J. (2023). Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of melanoma, version 3.0. Journal for ImmunoTherapy of Cancer, 11(10), e006947. https://doi.org/10.1136/jitc-2023-006947
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Mckean, M., Chmielowski, B., Butler, M. O., Carvajal, R., Rodon, J., Carlino, M., Kim, K. B., Wise-draper, T., Khan, S., Salama, A. K. S., Moser, J., Reeves, J., Wilner, K. D., Maurer, M., Abed, M., Mitchell, B., Beaupre, D., & Orloff, M. (2023). 1081O ctDNA reduction and clinical efficacy of the darovasertib + crizotinib (daro + crizo) combination in metastatic uveal melanoma (MUM). Annals of Oncology, 34, S651. https://doi.org/10.1016/j.annonc.2023.09.2215
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Kim, A., Zhu, Y., Chen, D., Elmais, M., Athar, M., & Bickers, D. R. (2023). LB1763 Combinatorial BRD9 and SMO targeting synergistically suppress UV-induced BCC tumor burden in a murine model of Gorlin syndrome (GS). Journal of Investigative Dermatology, 143(9), B28. https://doi.org/10.1016/j.jid.2023.06.143
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Bauer, S., Larkin, J., Hodi, F. S., Stephen, F., Kapiteijn, E. H. W., Schwartz, G. K., Calvo, E., Yerramilli-Rao, P., Piperno-Neumann, S., & Carvajal, R. D. (2023). A phase Ib trial of combined PKC and MEK inhibition with sotrastaurin and binimetinib in patients with metastatic uveal melanoma. Frontiers in Oncology, 12. https://doi.org/10.3389/fonc.2022.975642
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Jeong, J., Rand, G. M., Lee, J.-Y., & Kwon, J.-W. (2023). Novel limbal dermoid surgery for visual acuity and cosmesis improvement: A 7-year retrospective review. PLOS ONE, 18(6), e0286250. https://doi.org/10.1371/journal.pone.0286250
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Vize, C. J., Kim, S. K., Matthews, T., Macsai, M., Merrell, R., Hsu, S., Kundu, M. G., Yoon, J., Kennedy, E., Pai, M., Bain, E., Lassman, A. B., & Moazami, G. (2023). A Phase 3b Study for Management of Ocular Side Effects in Patients with Epidermal Growth Factor Receptor-Amplified Glioblastoma Receiving Depatuxizumab Mafodotin. Ophthalmic Research, 1030–1043. Portico. https://doi.org/10.1159/000531142
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Ambrosini, G., Natale, C. A., Musi, E., Garyantes, T., & Schwartz, G. K. (2023). The GPER Agonist LNS8801 Induces Mitotic Arrest and Apoptosis in Uveal Melanoma Cells. Cancer Research Communications, 3(4), 540–547. https://doi.org/10.1158/2767-9764.crc-22-0399
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Piperno-Neumann, S., Carlino, M. S., Boni, V., Loirat, D., Speetjens, F. M., Park, J. J., Calvo, E., Carvajal, R. D., Nyakas, M., Gonzalez-Maffe, J., Zhu, X., Shirley, M. D., Ramkumar, T., Fessehatsion, A., Burks, H. E., Yerramilli-Rao, P., & Kapiteijn, E. (2023). A phase I trial of LXS196, a protein kinase C (PKC) inhibitor, for metastatic uveal melanoma. British Journal of Cancer, 128(6), 1040–1051. https://doi.org/10.1038/s41416-022-02133-6
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Carvajal, R. D., Butler, M. O., Shoushtari, A. N., Hassel, J. C., Ikeguchi, A., Hernandez-Aya, L., Nathan, P., Hamid, O., Piulats, J. M., Rioth, M., Johnson, D. B., Luke, J. J., Espinosa, E., Leyvraz, S., Collins, L., Goodall, H. M., Ranade, K., Holland, C., Abdullah, S. E., … Sato, T. (2022). Clinical and molecular response to tebentafusp in previously treated patients with metastatic uveal melanoma: a phase 2 trial. Nature Medicine, 28(11), 2364–2373. https://doi.org/10.1038/s41591-022-02015-7
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Khan, S., Patel, S. P., Shoushtari, A. N., Ambrosini, G., Cremers, S., Lee, S., Franks, L., Singh-Kandah, S., Hernandez, S., Sender, N., Vuolo, K., Nesson, A., Mundi, P., Izar, B., Schwartz, G. K., & Carvajal, R. D. (2022). Intermittent MEK inhibition for the treatment of metastatic uveal melanoma. Frontiers in Oncology, 12. https://doi.org/10.3389/fonc.2022.975643
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Wei, A. Z., Uriel, M., Porcu, A., Manos, M. P., Mercurio, A. C., Caplan, M. M., Hulse, L., Seedor, R. S., Holovatska, M., Francis, J., Khan, S. A., McDonnell, D. E., Bogomolny, D., Sato, T., Marr, B. P., Haq, R., Orloff, M., Shoushtari, A., & Carvajal, R. D. (2022). Characterizing metastatic uveal melanoma patients who develop symptomatic brain metastases. Frontiers in Oncology, 12. https://doi.org/10.3389/fonc.2022.961517
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Sato, T., Ikeguchi, A. P., Nathan, P., Carvajal, R. D., Shoushtari, A. N., Gajewski, T. F., Hassel, J. C., Rioth, M., Leyvraz, S., Daniels, G. A., Hernandez-Aya, L., Johnson, D. B., Kim, K., Piulats Rodriguez, J. M., Cowey, C. L., Lockwood, S., Collins, L., Karakuzu, O., Sacco, J. J., & Butler, M. O. (2022). 843P Long-term survivors on tebentafusp in phase II trial of previously treated patients with metastatic uveal melanoma. Annals of Oncology, 33, S934–S935. https://doi.org/10.1016/j.annonc.2022.07.969
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Dimitriou, F., Hassel, J. C., Orloff, M., Hughes, I., Kapiteijn, E., Mehmi, I., Montazeri, K., Johnson, D. B., Grover, P., Gerard, C. L., Simeone, E., Gaudy Marqueste, C., Cheng, P., Long, G. V., Carvajal, R. D., & Dummer, R. (2022). 832P Treatment sequence with tebentafusp (tebe) and anti-PD1/ipilimumab (PD1+IPI) in HLA-A2*02:01 patients (pts) with metastatic uveal melanoma (mUM). Annals of Oncology, 33, S929. https://doi.org/10.1016/j.annonc.2022.07.958
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Khan, S., Lutzky, J., Shoushtari, A. N., Jeter, J., Marr, B., Olencki, T. E., Cebulla, C. M., Abdel-Rahman, M., Harbour, J. W., Sender, N., Nesson, A., Singh-Kandah, S., Hernandez, S., King, J., Katari, M. S., Dimapanat, L., Izard, S., Ambrosini, G., Surriga, O., … Carvajal, R. D. (2022). Adjuvant crizotinib in high-risk uveal melanoma following definitive therapy. Frontiers in Oncology, 12. https://doi.org/10.3389/fonc.2022.976837
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Gordon, K. G., Carvajal, R. D., Graham, S. L., & Houghton, O. M. (2022). The reporting of uveal melanoma cases to the cancer registry in North Carolina. Frontiers in Oncology, 12. https://doi.org/10.3389/fonc.2022.877599
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Al-Dalahmah, O. A., Wang, L., Hsiao, S. J., Lin, C.-C., Mansukhani, M. M., Canoll, P., Bruce, J. N., & Zanazzi, G. (2022). Pineal region ganglioglioma: A neoplasm with a bimodal age distribution. Surgical Neurology International, 13, 245. https://doi.org/10.25259/sni_443_2022
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Carvajal, R. D., Nathan, P., Sacco, J. J., Orloff, M., Hernandez-Aya, L. F., Yang, J., Luke, J. J., Butler, M. O., Stanhope, S., Collins, L., McAlpine, C., Holland, C., Abdullah, S. E., & Sato, T. (2022). Phase I Study of Safety, Tolerability, and Efficacy of Tebentafusp Using a Step-Up Dosing Regimen and Expansion in Patients With Metastatic Uveal Melanoma. Journal of Clinical Oncology, 40(17), 1939–1948. https://doi.org/10.1200/jco.21.01805
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Lin, W. V., Rand, G. M., Miller, M. L., Marr, B. P., & Suh, L. H. (2022). A case of sight threatening complications from topical 1% 5-fluorouracil in the treatment of ocular surface squamous neoplasia. American Journal of Ophthalmology Case Reports, 25, 101265. https://doi.org/10.1016/j.ajoc.2022.101265
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