A phase Ib trial of combined PKC and MEK inhibition with sotrastaurin and binimetinib in patients with metastatic uveal melanoma

Bauer, S., Larkin, J., Hodi, F. S., Stephen, F., Kapiteijn, E. H. W., Schwartz, G. K., Calvo, E., Yerramilli-Rao, P., Piperno-Neumann, S., & Carvajal, R. D. (2023). A phase Ib trial of combined PKC and MEK inhibition with sotrastaurin and binimetinib in patients with metastatic uveal melanoma. Frontiers in Oncology, 12. https://doi.org/10.3389/fonc.2022.975642
Authors:
Sebastian Bauer
James Larkin
F. Stephen Hodi
Stephen Jay Frank
Ellen Kapiteijn
Gary K. Schwartz
Emiliano Calvo
Padmaja Yerramilli-Rao
Sophie Piperno‐Neumann
Richard D. Carvajal
Affiliated Authors:
Gary K. Schwartz
Columbia Affiliation:
Subjects:
Ocular Cancer Research and Treatment (OpenAlex Topic)
Mammalian MAP Kinase Signaling Pathways (OpenAlex Topic)
Diagnosis and Treatment of Multiple Myeloma (OpenAlex Topic)
Author Keywords:
gna11
gnaq
mek
pkc
binimetinib
sotrastaurin
uveal melanoma
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Publication Type:
Article
Unique ID:
10.3389/fonc.2022.975642
PMID:
37359242
DOI:
10.3389/fonc.2022.975642
Journal:
Frontiers in Oncology
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
View PubMed Record

Record Created: