Management of asynchronous multifocal adult glioblastoma with loss of BRAFV600E -mutant clonality: a case report

Haile, H., Upadhyayula, P. S., Karlovich, E., Sisti, M. B., Gill, B. J. A., & Donovan, L. E. (2025). Management of asynchronous multifocal adult glioblastoma with loss of BRAFV600E -mutant clonality: a case report. Acta Neuropathologica Communications, 13(1). https://doi.org/10.1186/s40478-024-01894-w
Authors:
Hannah Haile
Pavan S. Upadhyayula
Esma Karlovich
Michael B. Sisti
Brian J.A. Gill
Laura Donovan
Affiliated Authors:
Hannah Haile
Pavan S. Upadhyayula
Esma Karlovich
Michael B. Sisti
Brian J.A. Gill
Laura Donovan
Columbia Affiliation:
Subjects:
Glioblastoma (MeSH)
Proto-Oncogene Proteins B-raf (MeSH)
Brain Neoplasms (MeSH)
Gliomas (OpenAlex Topic)
Ocular Cancer Research and Treatment (OpenAlex Topic)
Mammalian MAP Kinase Signaling Pathways (OpenAlex Topic)
Author Keywords:
glioblastoma
braf(v600e)
braf inhibitors
clonal evolution
targeted therapy
glioma
tumor heterogeneity
resistance mechanisms
dabrafenib
trametinib
brafv600e
elink
Publication Type:
Article
Unique ID:
10.1186/s40478-024-01894-w
PMID:
39871343
DOI:
10.1186/s40478-024-01894-w
Journal:
Acta Neuropathologica Communications
Publication Date:
Data Source:
OpenAlex
Source Link:
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Record Created: