Detection and Management of Retinal Diseases

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Jalili, J., Walker, E., Bowd, C., Belghith, A., Goldbaum, M. H., Fazio, M. A., Girkin, C. A., De Moraes, C. G., Liebmann, J. M., Weinreb, R. N., Zangwill, L. M., & Christopher, M. (2025). Deep Learning Approach Predicts Longitudinal Retinal Nerve Fiber Layer Thickness Changes. Bioengineering, 12(2), 139. https://doi.org/10.3390/bioengineering12020139
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Hood, D. C., La Bruna, S., Durbin, M., Lee, C., Guzman, A., Gebhardt, T., Wang, Y., Stowman, A. L., De Moraes, C. G., Chaglasian, M., & Tsamis, E. (2024). A Pattern-Based OCT Metric for Glaucoma Detection. Translational Vision Science & Technology, 13(12), 21. https://doi.org/10.1167/tvst.13.12.21
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Tian, Y., Sharma, A., Mehta, S., Kaushal, S., Liebmann, J. M., Cioffi, G. A., & Thakoor, K. A. (2024). Automated Identification of Clinically Relevant Regions in Glaucoma OCT Reports Using Expert Eye Tracking Data and Deep Learning. Translational Vision Science & Technology, 13(10), 24. https://doi.org/10.1167/tvst.13.10.24
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Hood, D. C., Durbin, M., La Bruna, S., Lee, C., Hsiao, Y. S., El-Nimri, N. W., De Moraes, C. G., & Tsamis, E. (2024). Characteristics of a Large Database of Healthy Eyes From Optometry Practices: Implications for a Real-World Reference Database. Translational Vision Science & Technology, 13(10), 8. https://doi.org/10.1167/tvst.13.10.8
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Holste, G., Lin, M., Zhou, R., Wang, F., Liu, L., Yan, Q., Van Tassel, S. H., Kovacs, K., Chew, E. Y., Lu, Z., Wang, Z., & Peng, Y. (2024). Harnessing the power of longitudinal medical imaging for eye disease prognosis using Transformer-based sequence modeling. Npj Digital Medicine, 7(1). https://doi.org/10.1038/s41746-024-01207-4
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Shi, M., Lokhande, A., Tian, Y., Luo, Y., Eslami, M., Kazeminasab, S., Elze, T., Shen, L. Q., Pasquale, L. R., Wellik, S. R., De Moraes, C. G., Myers, J. S., Zebardast, N., Friedman, D. S., Boland, M. V., & Wang, M. (2024). Transformer-Based Deep Learning Prediction of 10-Degree Humphrey Visual Field Tests From 24-Degree Data. Translational Vision Science & Technology, 13(8), 11. https://doi.org/10.1167/tvst.13.8.11
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Lin, T.-Y., Yu-Chuan Kang, E., Wang, N.-K., Kang, J.-H., Chen, K.-J., Wu, W.-C., Lai, C.-C., & Hwang, Y.-S. (2024). Association Between Pentoxifylline Use and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease: A Multi-Institutional Cohort Study. Biomedical Journal, 100771. https://doi.org/10.1016/j.bj.2024.100771
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Hood, D. C., La Bruna, S., Durbin, M., Lee, C., Hsiao, Y. S., De Moraes, C. G., & Tsamis, E. (2024). Anatomical Features can Affect OCT Measures Used for Clinical Decisions and Clinical Trial Endpoints. Translational Vision Science & Technology, 13(4), 27. https://doi.org/10.1167/tvst.13.4.27
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Yalla, G. R., Hyman, N., Hock, L. E., Zhang, Q., Shukla, A. G., & Kolomeyer, N. N. (2024). Performance of Artificial Intelligence Chatbots on Glaucoma Questions Adapted From Patient Brochures. Cureus. https://doi.org/10.7759/cureus.56766
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Singh, R. K., Smith, S., Fingert, J., Gordon, M., Kass, M., Scheetz, T., Segrè, A. V., Wiggs, J., Elze, T., & Zebardast, N. (2024). Machine Learning–Derived Baseline Visual Field Patterns Predict Future Glaucoma Onset in the Ocular Hypertension Treatment Study. Investigative Opthalmology & Visual Science, 65(2), 35. https://doi.org/10.1167/iovs.65.2.35
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El Husseini, N., Schaich, C. L., Craft, S., Rapp, S. R., Hayden, K. M., Sharrett, R., Cotch, M. F., Wong, T. Y., Luchsinger, J. A., Espeland, M. A., Baker, L. D., Bertoni, A. G., & Hughes, T. M. (2024). Retinal vessel caliber and cognitive performance: the multi-ethnic study of atherosclerosis (MESA). Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-54412-2
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Feenstra, H. M. A., van Dijk, E. H. C., Cheung, C. M. G., Ohno-Matsui, K., Lai, T. Y. Y., Koizumi, H., Larsen, M., Querques, G., Downes, S. M., Yzer, S., Breazzano, M. P., Subhi, Y., Tadayoni, R., Priglinger, S. G., Pauleikhoff, L. J. B., Lange, C. A. K., Loewenstein, A., Diederen, R. M. H., Schlingemann, R. O., … Boon, C. J. F. (2024). Central serous chorioretinopathy: An evidence-based treatment guideline. Progress in Retinal and Eye Research, 101, 101236. https://doi.org/10.1016/j.preteyeres.2024.101236
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Christopher, M., Gonzalez, R., Huynh, J., Walker, E., Radha Saseendrakumar, B., Bowd, C., Belghith, A., Goldbaum, M. H., Fazio, M. A., Girkin, C. A., De Moraes, C. G., Liebmann, J. M., Weinreb, R. N., Baxter, S. L., & Zangwill, L. M. (2024). Proactive Decision Support for Glaucoma Treatment: Predicting Surgical Interventions with Clinically Available Data. Bioengineering, 11(2), 140. https://doi.org/10.3390/bioengineering11020140
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Chuter, B., Huynh, J., Bowd, C., Walker, E., Rezapour, J., Brye, N., Belghith, A., Fazio, M. A., Girkin, C. A., De Moraes, G., Liebmann, J. M., Weinreb, R. N., Zangwill, L. M., & Christopher, M. (2024). Deep Learning Identifies High-Quality Fundus Photographs and Increases Accuracy in Automated Primary Open Angle Glaucoma Detection. Translational Vision Science & Technology, 13(1), 23. https://doi.org/10.1167/tvst.13.1.23
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Leshno, A., Tsamis, E., Hirji, S., Gomide, G. A., Harizman, N., De Moraes, C. G., Garg Shukla, A., Cioffi, G. A., Hood, D. C., & Liebmann, J. M. (2024). Detecting Established Glaucoma Using OCT Alone: Utilizing an OCT Reading Center in a Real-World Clinical Setting. Translational Vision Science & Technology, 13(1), 4. https://doi.org/10.1167/tvst.13.1.4
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Leshno, A., Tsamis, E., Harizman, N., De Moraes, C. G., La Bruna, S., Rai, A., Garg-Shukla, A., Cioffi, G. A., Wang, Q., Liebmann, J. M., & Hood, D. C. (2023). Improving glaucoma staging in clinical practice by combining the ICD-10 glaucoma severity classification system and optical coherence tomography. Eye, 38(1), 153–160. https://doi.org/10.1038/s41433-023-02650-5
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Hood, D. C., La Bruna, S., Leshno, A., Gomide, G. A., Kim, M. J., Cioffi, G. A., Liebmann, J. M., De Moraes, C. G., & Tsamis, E. (2023). A Model of Progression to Help Identify Macular Damage Due to Glaucoma. Investigative Opthalmology & Visual Science, 64(15), 8. https://doi.org/10.1167/iovs.64.15.8
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Javitt, D. C., Martinez, A., Sehatpour, P., Beloborodova, A., Habeck, C., Gazes, Y., Bermudez, D., Razlighi, Q. R., Devanand, D. P., & Stern, Y. (2023). Disruption of early visual processing in amyloid-positive healthy individuals and mild cognitive impairment. Alzheimer’s Research & Therapy, 15(1). https://doi.org/10.1186/s13195-023-01189-7
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Ong, S. S., Peavey, J. J., Hiatt, K. D., Whitlow, C. T., Sappington, R. M., Thompson, A. C., Lockhart, S. N., Chen, H., Craft, S., Rapp, S. R., Fitzpatrick, A. L., Heckbert, S. R., Luchsinger, J. A., Klein, B. E. K., Meuer, S. M., Cotch, M. F., Wong, T. Y., & Hughes, T. M. (2023). Association of fractal dimension and other retinal vascular network parameters with cognitive performance and neuroimaging biomarkers: The Multi‐Ethnic Study of Atherosclerosis (MESA). Alzheimer’s & Dementia, 20(2), 941–953. Portico. https://doi.org/10.1002/alz.13498
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Mahmoudinezhad, G., Nishida, T., Weinreb, R. N., Baxter, S. L., Chang, A. C., Nikkhoy, N., Walker, E., Liebmann, J. M., Girkin, C. A., & Moghimi, S. (2023). Associations of smoking and alcohol consumption with the development of open angle glaucoma: a retrospective cohort study. BMJ Open, 13(10), e072163. https://doi.org/10.1136/bmjopen-2023-072163
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Akerman, M., Choudhary, S., Liebmann, J. M., Cioffi, G. A., Chen, R. W. S., & Thakoor, K. A. (2023). Extracting decision-making features from the unstructured eye movements of clinicians on glaucoma OCT reports and developing AI models to classify expertise. Frontiers in Medicine, 10. https://doi.org/10.3389/fmed.2023.1251183
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Kang, E. Y.-C., Lin, T.-Y., Garg, S. J., Wang, N.-K., Chen, L.-J., Huang, P.-W., Chan, M.-J., Chen, K.-J., Wu, W.-C., Lai, C.-C., & Hwang, Y.-S. (2023). The Association of Intravitreal Injections of Different Anti-Vascular Endothelial Growth Factor with Systemic Outcomes in Diabetic Patients. Journal of Personalized Medicine, 13(3), 544. https://doi.org/10.3390/jpm13030544
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Fan, R., Alipour, K., Bowd, C., Christopher, M., Brye, N., Proudfoot, J. A., Goldbaum, M. H., Belghith, A., Girkin, C. A., Fazio, M. A., Liebmann, J. M., Weinreb, R. N., Pazzani, M., Kriegman, D., & Zangwill, L. M. (2023). Detecting Glaucoma from Fundus Photographs Using Deep Learning without Convolutions. Ophthalmology Science, 3(1), 100233. https://doi.org/10.1016/j.xops.2022.100233
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Qian, T., Gong, Q., Shen, H., Li, C., Wang, G., Xu, X., Schrauwen, I., & Wang, W. (2022). Novel variants in the RDH5 Gene in a Chinese Han family with fundus albipunctatus. BMC Ophthalmology, 22(1). https://doi.org/10.1186/s12886-022-02301-5
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Thakoor, K. A., Yao, J., Bordbar, D., Moussa, O., Lin, W., Sajda, P., & Chen, R. W. S. (2022). A multimodal deep learning system to distinguish late stages of AMD and to compare expert vs. AI ocular biomarkers. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-06273-w
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White, N. H., Pan, Q., Knowler, W. C., Schroeder, E. B., Dabelea, D., Chew, E. Y., Blodi, B., Goldberg, R. B., Pi-Sunyer, X., Darwin, C., Schlögl, M., Nathan, D. M., Bray, G. A., Gadde, K. M., Culbert, I. W., Arceneaux, J., Chatellier, A., Dragg, A., … Brown, M. B. (2022). Risk Factors for the Development of Retinopathy in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Experience. Diabetes Care, 45(11), 2653–2661. https://doi.org/10.2337/dc22-0860
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Shokr, H., Lush, V., Dias, I. H., Ekárt, A., De Moraes, G., & Gherghel, D. (2022). The Use of Retinal Microvascular Function and Telomere Length in Age and Blood Pressure Prediction in Individuals with Low Cardiovascular Risk. Cells, 11(19), 3037. https://doi.org/10.3390/cells11193037
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Melgarejo, J. D., Eijgen, J. V., Maestre, G. E., Al-Aswad, L. A., Thijs, L., Mena, L. J., Lee, J. H., Terwilliger, J. D., Petitto, M., Chávez, C. A., Brito, M., Calmon, G., Silva, E., Wei, D.-M., Cutsforth, E., Keer, K. V., Gustavo De Moraes, C., Vanassche, T., Janssens, S., … Zhang, Z.-Y. (2022). Open-Angle Glaucomatous Optic Neuropathy Is Related to Dips Rather Than Increases in the Mean Arterial Pressure Over 24-H. American Journal of Hypertension, 35(8), 703–714. https://doi.org/10.1093/ajh/hpac028
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Zemborain, Z. Z., Tsamis, E., La Bruna, S., Leshno, A., De Moraes, C. G., & Hood, D. C. (2022). Test of a Retinal Nerve Fiber Bundle Trajectory Model Using Eyes With Glaucomatous Optic Neuropathy. Translational Vision Science & Technology, 11(7), 7. https://doi.org/10.1167/tvst.11.7.7
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White, N. H., Pan, Q., Knowler, W. C., Schroeder, E. B., Dabelea, D., Chew, E. Y., Blodi, B., Goldberg, R. B., Pi-Sunyer, X., Darwin, C., Schlögl, M., Nathan, D. M., Goldstein, B. J., Furlong, K., Smith, K. A., Mendoza, J., Wildman, W., Simmons, M., … Hivert, M.-F. (2022). The Effect of Interventions to Prevent Type 2 Diabetes on the Development of Diabetic Retinopathy: The DPP/DPPOS Experience. Diabetes Care, 45(7), 1640–1646. https://doi.org/10.2337/dc21-2417
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La Bruna, S., Rai, A., Mao, G., Kerr, J., Amin, H., Zemborain, Z. Z., Leshno, A., Tsamis, E., De Moraes, C. G., & Hood, D. C. (2022). The OCT RNFL Probability Map and Artifacts Resembling Glaucomatous Damage. Translational Vision Science & Technology, 11(3), 18. https://doi.org/10.1167/tvst.11.3.18
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Nicolela Susanna, C., Nicolela Susanna, B., Nicolela Susanna, F., & Susanna Jr, R. (2022). Peak Intraocular Pressure Time during Water Drinking Test and Its Relationship with Glaucoma Severity. Journal of Ophthalmic and Vision Research, 17(1). https://doi.org/10.18502/jovr.v17i1.10167
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Blodi, B. A., Domalpally, A., Tjaden, A. H., Barrett, N., Chew, E. Y., Knowler, W. C., Lee, C. G., Pi-Sunyer, X., Wallia, A., White, N. H., & Temprosa, M. (2022). Comparison of ETDRS 7-Field to 4-Widefield Digital Imaging in the Evaluation of Diabetic Retinopathy Severity. Translational Vision Science & Technology, 11(1), 13. https://doi.org/10.1167/tvst.11.1.13
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Barua, P. D., Chan, W. Y., Dogan, S., Baygin, M., Tuncer, T., Ciaccio, E. J., Islam, N., Cheong, K. H., Shahid, Z. S., & Acharya, U. R. (2021). Multilevel Deep Feature Generation Framework for Automated Detection of Retinal Abnormalities Using OCT Images. Entropy, 23(12), 1651. https://doi.org/10.3390/e23121651
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Al-Aswad, L. A., Elgin, C. Y., Patel, V., Popplewell, D., Gopal, K., Gong, D., Thomas, Z., Joiner, D., Chu, C.-K., Walters, S., Ramachandran, M., Kapoor, R., Rodriguez, M., Alcantara-Castillo, J., Maestre, G. E., Lee, J. H., & Moazami, G. (2021). Real-Time Mobile Teleophthalmology for the Detection of Eye Disease in Minorities and Low Socioeconomics At-Risk Populations. Asia-Pacific Journal of Ophthalmology, 10(5), 461–472. https://doi.org/10.1097/apo.0000000000000416
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