Amyloid beta-Protein Precursor

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Qu, W., Lam, M., McInvale, J. J., Mares, J. A., Kwon, S., Humala, N., Mahajan, A., Nguyen, T., Jakubiak, K. A., Mun, J.-Y., Tedesco, T. G., Al-Dalahmah, O., Hussaini, S. A., Sproul, A. A., Siegelin, M. D., De Jager, P. L., Canoll, P., Menon, V., & Hargus, G. (2024). Xenografted human iPSC-derived neurons with the familial Alzheimer’s disease APPV717I mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediator. Acta Neuropathologica, 147(1). https://doi.org/10.1007/s00401-024-02755-5
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Puliatti, G., Li Puma, D. D., Aceto, G., Lazzarino, G., Acquarone, E., Mangione, R., D’Adamio, L., Ripoli, C., Arancio, O., Piacentini, R., & Grassi, C. (2023). Intracellular accumulation of tau oligomers in astrocytes and their synaptotoxic action rely on Amyloid Precursor Protein Intracellular Domain-dependent expression of Glypican-4. Progress in Neurobiology, 227, 102482. https://doi.org/10.1016/j.pneurobio.2023.102482
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