Global Prevalence and Treatment of Glaucoma

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Rodriguez, J., Hamm, A., Bensinger, E., Kerti, S., Gomes, P., Ousler III, G., Gupta, P., De Moraes, C., & Abelson, M. (2025). Statistical Evaluation of Smartphone-Based Automated Grading System for Ocular Redness Associated with Dry Eye Disease and Implications for Clinical Trials. Clinical Ophthalmology, Volume 19, 907–914. https://doi.org/10.2147/opth.s506519
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Jalili, J., Walker, E., Bowd, C., Belghith, A., Goldbaum, M. H., Fazio, M. A., Girkin, C. A., De Moraes, C. G., Liebmann, J. M., Weinreb, R. N., Zangwill, L. M., & Christopher, M. (2025). Deep Learning Approach Predicts Longitudinal Retinal Nerve Fiber Layer Thickness Changes. Bioengineering, 12(2), 139. https://doi.org/10.3390/bioengineering12020139
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Kizhatil, K., Clark, G. M., Sunderland, D. K., Bhandari, A., Horbal, L. J., Balasubramanian, R., & John, S. W. M. (2025). FYN regulates aqueous humor outflow and IOP through the phosphorylation of VE-CADHERIN. Nature Communications, 16(1). https://doi.org/10.1038/s41467-024-55232-8
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Susanna, C. T., De Moraes, C. G., Alhadeff, P., Susanna, B., Susanna, F., Germano, R. A. S., & Susanna, R. (2024). Reproducibility of Peaks During Water-drinking Test in Patients Treated for Open-angle Glaucoma. Journal of Ophthalmic and Vision Research, 19(4). https://doi.org/10.18502/jovr.v19i4.14982
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Hood, D. C., La Bruna, S., Durbin, M., Lee, C., Guzman, A., Gebhardt, T., Wang, Y., Stowman, A. L., De Moraes, C. G., Chaglasian, M., & Tsamis, E. (2024). A Pattern-Based OCT Metric for Glaucoma Detection. Translational Vision Science & Technology, 13(12), 21. https://doi.org/10.1167/tvst.13.12.21
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Gordon, M. O., Heuer, D. K., Higginbotham, E. J., Parrish, R. K., Liu, L., Brandt, J. D., Huecker, J. B., Miller, J. P., Perera, C., Xie, C., Keltner, J. L., Johnson, C. A., Gardiner, S. K., Liebmann, J. M., & Kass, M. A. (2024). Visual Field Progression in the Ocular Hypertension Treatment Study. American Journal of Ophthalmology. https://doi.org/10.1016/j.ajo.2024.11.017
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Tian, Y., Sharma, A., Mehta, S., Kaushal, S., Liebmann, J. M., Cioffi, G. A., & Thakoor, K. A. (2024). Automated Identification of Clinically Relevant Regions in Glaucoma OCT Reports Using Expert Eye Tracking Data and Deep Learning. Translational Vision Science & Technology, 13(10), 24. https://doi.org/10.1167/tvst.13.10.24
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Hood, D. C., Durbin, M., La Bruna, S., Lee, C., Hsiao, Y. S., El-Nimri, N. W., De Moraes, C. G., & Tsamis, E. (2024). Characteristics of a Large Database of Healthy Eyes From Optometry Practices: Implications for a Real-World Reference Database. Translational Vision Science & Technology, 13(10), 8. https://doi.org/10.1167/tvst.13.10.8
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Holste, G., Lin, M., Zhou, R., Wang, F., Liu, L., Yan, Q., Van Tassel, S. H., Kovacs, K., Chew, E. Y., Lu, Z., Wang, Z., & Peng, Y. (2024). Harnessing the power of longitudinal medical imaging for eye disease prognosis using Transformer-based sequence modeling. Npj Digital Medicine, 7(1). https://doi.org/10.1038/s41746-024-01207-4
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Shi, M., Lokhande, A., Tian, Y., Luo, Y., Eslami, M., Kazeminasab, S., Elze, T., Shen, L. Q., Pasquale, L. R., Wellik, S. R., De Moraes, C. G., Myers, J. S., Zebardast, N., Friedman, D. S., Boland, M. V., & Wang, M. (2024). Transformer-Based Deep Learning Prediction of 10-Degree Humphrey Visual Field Tests From 24-Degree Data. Translational Vision Science & Technology, 13(8), 11. https://doi.org/10.1167/tvst.13.8.11
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Lin, T.-Y., Yu-Chuan Kang, E., Wang, N.-K., Kang, J.-H., Chen, K.-J., Wu, W.-C., Lai, C.-C., & Hwang, Y.-S. (2024). Association Between Pentoxifylline Use and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease: A Multi-Institutional Cohort Study. Biomedical Journal, 100771. https://doi.org/10.1016/j.bj.2024.100771
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Hood, D. C., La Bruna, S., Durbin, M., Lee, C., Hsiao, Y. S., De Moraes, C. G., & Tsamis, E. (2024). Anatomical Features can Affect OCT Measures Used for Clinical Decisions and Clinical Trial Endpoints. Translational Vision Science & Technology, 13(4), 27. https://doi.org/10.1167/tvst.13.4.27
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Singh, R. K., Smith, S., Fingert, J., Gordon, M., Kass, M., Scheetz, T., Segrè, A. V., Wiggs, J., Elze, T., & Zebardast, N. (2024). Machine Learning–Derived Baseline Visual Field Patterns Predict Future Glaucoma Onset in the Ocular Hypertension Treatment Study. Investigative Opthalmology & Visual Science, 65(2), 35. https://doi.org/10.1167/iovs.65.2.35
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Christopher, M., Gonzalez, R., Huynh, J., Walker, E., Radha Saseendrakumar, B., Bowd, C., Belghith, A., Goldbaum, M. H., Fazio, M. A., Girkin, C. A., De Moraes, C. G., Liebmann, J. M., Weinreb, R. N., Baxter, S. L., & Zangwill, L. M. (2024). Proactive Decision Support for Glaucoma Treatment: Predicting Surgical Interventions with Clinically Available Data. Bioengineering, 11(2), 140. https://doi.org/10.3390/bioengineering11020140
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Chuter, B., Huynh, J., Bowd, C., Walker, E., Rezapour, J., Brye, N., Belghith, A., Fazio, M. A., Girkin, C. A., De Moraes, G., Liebmann, J. M., Weinreb, R. N., Zangwill, L. M., & Christopher, M. (2024). Deep Learning Identifies High-Quality Fundus Photographs and Increases Accuracy in Automated Primary Open Angle Glaucoma Detection. Translational Vision Science & Technology, 13(1), 23. https://doi.org/10.1167/tvst.13.1.23
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Gad, R. E., Kahn, J., & Trief, D. (2024). Spontaneous Reattachment of a Detached Sutured Descemet-Stripping Automated Endothelial Keratoplasty Graft. Case Reports in Ophthalmology, 15(1), 41–46. Portico. https://doi.org/10.1159/000535402
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Leshno, A., Tsamis, E., Hirji, S., Gomide, G. A., Harizman, N., De Moraes, C. G., Garg Shukla, A., Cioffi, G. A., Hood, D. C., & Liebmann, J. M. (2024). Detecting Established Glaucoma Using OCT Alone: Utilizing an OCT Reading Center in a Real-World Clinical Setting. Translational Vision Science & Technology, 13(1), 4. https://doi.org/10.1167/tvst.13.1.4
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Verma, S. S., Gudiseva, H. V., Chavali, V. R. M., Salowe, R. J., Bradford, Y., Guare, L., Lucas, A., Collins, D. W., Vrathasha, V., Nair, R. M., Rathi, S., Zhao, B., He, J., Lee, R., Zenebe-Gete, S., Bowman, A. S., McHugh, C. P., Zody, M. C., Pistilli, M., … O’Brien, J. M. (2024). A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma. Cell, 187(2), 464-480.e10. https://doi.org/10.1016/j.cell.2023.12.006
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Oliveira, M. A., Senger, C., Souza, R. P., Moraes, C. G. de, Messias, A., & Paula, J. S. (2024). Saccadic movements during an exploratory visual search task in patients with glaucomatous visual field loss. Arquivos Brasileiros de Oftalmologia, 87(3). https://doi.org/10.5935/0004-2749.2022-0366
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Leshno, A., Tsamis, E., Harizman, N., De Moraes, C. G., La Bruna, S., Rai, A., Garg-Shukla, A., Cioffi, G. A., Wang, Q., Liebmann, J. M., & Hood, D. C. (2023). Improving glaucoma staging in clinical practice by combining the ICD-10 glaucoma severity classification system and optical coherence tomography. Eye, 38(1), 153–160. https://doi.org/10.1038/s41433-023-02650-5
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Hood, D. C., La Bruna, S., Leshno, A., Gomide, G. A., Kim, M. J., Cioffi, G. A., Liebmann, J. M., De Moraes, C. G., & Tsamis, E. (2023). A Model of Progression to Help Identify Macular Damage Due to Glaucoma. Investigative Opthalmology & Visual Science, 64(15), 8. https://doi.org/10.1167/iovs.64.15.8
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Javitt, D. C., Martinez, A., Sehatpour, P., Beloborodova, A., Habeck, C., Gazes, Y., Bermudez, D., Razlighi, Q. R., Devanand, D. P., & Stern, Y. (2023). Disruption of early visual processing in amyloid-positive healthy individuals and mild cognitive impairment. Alzheimer’s Research & Therapy, 15(1). https://doi.org/10.1186/s13195-023-01189-7
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Ong, S. S., Peavey, J. J., Hiatt, K. D., Whitlow, C. T., Sappington, R. M., Thompson, A. C., Lockhart, S. N., Chen, H., Craft, S., Rapp, S. R., Fitzpatrick, A. L., Heckbert, S. R., Luchsinger, J. A., Klein, B. E. K., Meuer, S. M., Cotch, M. F., Wong, T. Y., & Hughes, T. M. (2023). Association of fractal dimension and other retinal vascular network parameters with cognitive performance and neuroimaging biomarkers: The Multi‐Ethnic Study of Atherosclerosis (MESA). Alzheimer’s & Dementia, 20(2), 941–953. Portico. https://doi.org/10.1002/alz.13498
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Mahmoudinezhad, G., Nishida, T., Weinreb, R. N., Baxter, S. L., Chang, A. C., Nikkhoy, N., Walker, E., Liebmann, J. M., Girkin, C. A., & Moghimi, S. (2023). Associations of smoking and alcohol consumption with the development of open angle glaucoma: a retrospective cohort study. BMJ Open, 13(10), e072163. https://doi.org/10.1136/bmjopen-2023-072163
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Akerman, M., Choudhary, S., Liebmann, J. M., Cioffi, G. A., Chen, R. W. S., & Thakoor, K. A. (2023). Extracting decision-making features from the unstructured eye movements of clinicians on glaucoma OCT reports and developing AI models to classify expertise. Frontiers in Medicine, 10. https://doi.org/10.3389/fmed.2023.1251183
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Moster, M. R., Shalaby, W. S., Myers, J. S., Razeghinejad, R., Ramesh, S., Katz, L. J., Kolomeyer, N. N., Lee, D., & Shukla, A. G. (2023). Evaluation of the Hypertensive Phase after Ahmed Glaucoma Valve Implantation in Neovascular Glaucoma. Journal of Current Glaucoma Practice, 17(2), 91–97. https://doi.org/10.5005/jp-journals-10078-1406
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Ambrósio, R., Machado, A. P., Leão, E., Lyra, J. M. G., Salomão, M. Q., Esporcatte, L. G. P., da Fonseca Filho, J. B. R., Ferreira-Meneses, E., Sena, N. B., Haddad, J. S., Costa Neto, A., de Almeida, G. C., Roberts, C. J., Elsheikh, A., Vinciguerra, R., Vinciguerra, P., Bühren, J., Kohnen, T., Kezirian, G. M., … Lopes, B. T. (2023). Optimized Artificial Intelligence for Enhanced Ectasia Detection Using Scheimpflug-Based Corneal Tomography and Biomechanical Data. American Journal of Ophthalmology, 251, 126–142. https://doi.org/10.1016/j.ajo.2022.12.016
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Greenstein, V. C., Castillejos, D. S., Tsang, S. H., Lee, W., Sparrow, J. R., Allikmets, R., Birch, D. G., & Hood, D. C. (2023). Monitoring Lesion Area Progression in Stargardt Disease: A Comparison of En Face Optical Coherence Tomography and Fundus Autofluorescence. Translational Vision Science & Technology, 12(5), 2. https://doi.org/10.1167/tvst.12.5.2
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Shukla, A. G., Milman, T., Fertala, J., Steplewski, A., & Fertala, A. (2023). Scar formation in the presence of mitomycin C and the anti-fibrotic antibody in a rabbit model of glaucoma microsurgery: A pilot study. Heliyon, 9(4), e15368. https://doi.org/10.1016/j.heliyon.2023.e15368
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Tsamis, E., La Bruna, S., Rai, A., Leshno, A., Grossman, J., Cioffi, G., Liebmann, J. M., De Moraes, C. G., & Hood, D. C. (2023). Progression of Early Glaucomatous Damage: Performance of Summary Statistics From Optical Coherence Tomography and Perimetry. Translational Vision Science & Technology, 12(3), 19. https://doi.org/10.1167/tvst.12.3.19
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Fan, R., Alipour, K., Bowd, C., Christopher, M., Brye, N., Proudfoot, J. A., Goldbaum, M. H., Belghith, A., Girkin, C. A., Fazio, M. A., Liebmann, J. M., Weinreb, R. N., Pazzani, M., Kriegman, D., & Zangwill, L. M. (2023). Detecting Glaucoma from Fundus Photographs Using Deep Learning without Convolutions. Ophthalmology Science, 3(1), 100233. https://doi.org/10.1016/j.xops.2022.100233
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Hood, D. C., La Bruna, S., Tsamis, E., Leshno, A., Melchior, B., Grossman, J., Liebmann, J. M., & De Moraes, C. G. (2022). The 24-2 Visual Field Guided Progression Analysis Can Miss the Progression of Glaucomatous Damage of the Macula Seen Using OCT. Ophthalmology Glaucoma, 5(6), 614–627. https://doi.org/10.1016/j.ogla.2022.03.007
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Miller, S. C., Meeralakshmi, P., Fliotsos, M. J., Justin, G. A., Yonekawa, Y., Chen, A., Hoskin, A. K., Blanch, R. J., Cavuoto, K. M., Low, R., Li, X., Gardiner, M., Liu, T. A., Shah, A. S., Auran, J. D., Agrawal, R., & Woreta, F. A. (2022). Global Current Practice Patterns for the Management of Hyphema. Clinical Ophthalmology, Volume 16, 3135–3144. https://doi.org/10.2147/opth.s372273
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Nishida, T., Moghimi, S., Mohammadzadeh, V., Wu, J.-H., Yamane, M. L. M., Kamalipour, A., Mahmoudinezhad, G., Micheletti, E., Liebmann, J. M., Fazio, M. A., Girkin, C. A., Zangwill, L. M., & Weinreb, R. N. (2022). Association Between Ganglion Cell Complex Thinning and Vision-Related Quality of Life in Glaucoma. JAMA Ophthalmology. https://doi.org/10.1001/jamaophthalmol.2022.2140
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Melgarejo, J. D., Eijgen, J. V., Maestre, G. E., Al-Aswad, L. A., Thijs, L., Mena, L. J., Lee, J. H., Terwilliger, J. D., Petitto, M., Chávez, C. A., Brito, M., Calmon, G., Silva, E., Wei, D.-M., Cutsforth, E., Keer, K. V., Gustavo De Moraes, C., Vanassche, T., Janssens, S., … Zhang, Z.-Y. (2022). Open-Angle Glaucomatous Optic Neuropathy Is Related to Dips Rather Than Increases in the Mean Arterial Pressure Over 24-H. American Journal of Hypertension, 35(8), 703–714. https://doi.org/10.1093/ajh/hpac028
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Kim, J., Men, C. J., Ratanawongphaibul, K., Papadogeorgou, G., Tsikata, E., Ben-David, G. S., Antar, H., Poon, L. Y.-C., Freeman, M., Park, E. A., Guzman Aparicio, M. A., de Boer, J. F., & Chen, T. C. (2022). Reproducibility of Neuroretinal Rim Measurements Obtained from High-Density Spectral Domain Optical Coherence Tomography Volume Scans. Clinical Ophthalmology, Volume 16, 2595–2608. https://doi.org/10.2147/opth.s369807
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Zemborain, Z. Z., Tsamis, E., La Bruna, S., Leshno, A., De Moraes, C. G., & Hood, D. C. (2022). Test of a Retinal Nerve Fiber Bundle Trajectory Model Using Eyes With Glaucomatous Optic Neuropathy. Translational Vision Science & Technology, 11(7), 7. https://doi.org/10.1167/tvst.11.7.7
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Villasana, G. A., Bradley, C., Elze, T., Myers, J. S., Pasquale, L., De Moraes, C. G., Wellik, S., Boland, M. V., Ramulu, P., Hager, G., Unberath, M., & Yohannan, J. (2022). Improving Visual Field Forecasting by Correcting for the Effects of Poor Visual Field Reliability. Translational Vision Science & Technology, 11(5), 27. https://doi.org/10.1167/tvst.11.5.27
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La Bruna, S., Rai, A., Mao, G., Kerr, J., Amin, H., Zemborain, Z. Z., Leshno, A., Tsamis, E., De Moraes, C. G., & Hood, D. C. (2022). The OCT RNFL Probability Map and Artifacts Resembling Glaucomatous Damage. Translational Vision Science & Technology, 11(3), 18. https://doi.org/10.1167/tvst.11.3.18
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Nicolela Susanna, C., Nicolela Susanna, B., Nicolela Susanna, F., & Susanna Jr, R. (2022). Peak Intraocular Pressure Time during Water Drinking Test and Its Relationship with Glaucoma Severity. Journal of Ophthalmic and Vision Research, 17(1). https://doi.org/10.18502/jovr.v17i1.10167
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