Plasmodium falciparum African PfCRT Mutant Isoforms Conducive to Piperaquine Resistance are Infrequent and Impart a Major Fitness Cost

Hagenah, L. M., Yeo, T., Schindler, K. A., Jeon, J. H., Bloxham, T. S., Small-Saunders, J. L., Mok, S., & Fidock, D. A. (2024). Plasmodium falciparum African PfCRT Mutant Isoforms Conducive to Piperaquine Resistance Are Infrequent and Impart a Major Fitness Cost. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiae617
Authors:
Laura M. Hagenah
Tomas Yeo
Kyra A. Schindler
Jin Yong Jeon
Talia S. Bloxham
Jennifer L. Small-Saunders
Sachel Mok
David A. Fidock
Affiliated Authors:
Laura M. Hagenah
Tomas Yeo
Kyra A. Schindler
Jin Yong Jeon
Talia S. Bloxham
Jennifer L. Small-Saunders
Sachel Mok
David A. Fidock
Columbia Affiliation:
Subjects:
Malaria (OpenAlex Topic)
Epilepsy and Seizures (OpenAlex Topic)
Efficacy and Safety of Antiretroviral Therapy for HIV (OpenAlex Topic)
Author Keywords:
plasmodium falciparum
pfcrt
antimalarial resistance
artemisinin-based combination therapy
fitness
malaria chemoprevention
piperaquine
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Publication Type:
Article
Unique ID:
10.1093/infdis/jiae617
PMID:
39661643
DOI:
10.1093/infdis/jiae617
Journal:
Journal of Infectious Diseases
Publication Date:
Data Source:
OpenAlex
Source Link:
View OpenAlex Record
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Record Created: