A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease

Nayar, S., Morrison, J. K., Giri, M., Gettler, K., Chuang, L., Walker, L. A., Ko, H. M., Kenigsberg, E., Kugathasan, S., Merad, M., Chu, J., & Cho, J. H. (2021). A myeloid–stromal niche and gp130 rescue in NOD2-driven Crohn’s disease. Nature, 593(7858), 275–281. https://doi.org/10.1038/s41586-021-03484-5
Authors:
Shikha Nayar
Joshua K Morrison
Mamta Giri
Kyle Gettler
Ling-Shiang Chuang
Laura A Walker
Huaibin M Ko
Ephraim Kenigsberg
Subra Kugathasan
Miriam Merad
Jaime Chu
Judy H Cho
Affiliated Authors:
Huaibin M Ko
Columbia Affiliation:
Subjects:
Crohn Disease (MeSH)
Cytokine Receptor gp130 (MeSH)
Myeloid Cells (MeSH)
Nod2 Signaling Adaptor Protein (MeSH)
Stromal Cells (MeSH)
Grants:
R01DK121154 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK123758 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
R01DK106593 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
U01DK062422 (NIH – National Institute of Diabetes and Digestive and Kidney Diseases)
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Publication Type:
Article
Unique ID:
10.1038/s41586-021-03484-5
PMID:
33789339
DOI:
10.1038/s41586-021-03484-5
Journal:
Nature
Publication Date:
Data Source:
PubMed
Source Link:
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