Transfer RNA-mediated restoration of potassium current and electrical correction in premature termination long-QT syndrome hERG mutants

Blomquist, V. G., Niu, J., Choudhury, P., Al Saneh, A., Colecraft, H. M., & Ahern, C. A. (2023). Transfer RNA-mediated restoration of potassium current and electrical correction in premature termination long-QT syndrome hERG mutants. Molecular Therapy - Nucleic Acids, 34, 102032. https://doi.org/10.1016/j.omtn.2023.102032

Authors:

Viggo G. Blomquist

Jacqueline Niu

Papiya Choudhury

Ahmad Al Saneh

Henry M. Colecraft

Christopher A. Ahern

Affiliated Authors:

Viggo G. Blomquist

Jacqueline Niu

Papiya Choudhury

Henry M. Colecraft

Columbia Affiliation:

Vagelos College of Physicians and Surgeons
- Department of Physiology and Cellular Biophysics
- Department of Molecular Pharmacology and Therapeutics

Subjects:

Ribosome Structure and Translation Mechanisms (OpenAlex Topic)

Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins (OpenAlex Topic)

Molecular Mechanisms of Cardiac Arrhythmias (OpenAlex Topic)

Author Keywords:

cardiac arrhythmia

ion channel

mt: oligonucleotides: trna therapies and applications

rna therapeutics

stop-codon readthrough

Publication Type:

Article

Unique ID:

10.1016/j.omtn.2023.102032

PMID:

DOI:

10.1016/j.omtn.2023.102032

Journal:

Molecular Therapy: Nucleic Acids

Publication Date:

2023-12-01

Data Source:

OpenAlex

Source Link:

View OpenAlex Record

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Record Created:

Tuesday, July 30, 2024 - 11:49