GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision

Asher, W. B., Terry, D. S., Gregorio, G. G. A., Kahsai, A. W., Borgia, A., Xie, B., Modak, A., Zhu, Y., Jang, W., Govindaraju, A., Huang, L.-Y., Inoue, A., Lambert, N. A., Gurevich, V. V., Shi, L., Lefkowitz, R. J., Blanchard, S. C., & Javitch, J. A. (2022). GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision. Cell, 185(10), 1661-1675.e16. https://doi.org/10.1016/j.cell.2022.03.042
Authors:
Wesley B. Asher
Daniel S. Terry
G. Glenn A. Gregorio
Alem W. Kahsai
Alessandro Borgia
Bing Xie
Arnab Modak
Ying Zhu
Wonjo Jang
Alekhya Govindaraju
Li-Yin Huang
Asuka Inoue
Nevin A. Lambert
Vsevolod V. Gurevich
Lei Shi
Robert J. Lefkowitz
Scott C. Blanchard
Jonathan A. Javitch
Affiliated Authors:
Wesley B. Asher
Ying Zhu
Jonathan A. Javitch
Author Keywords:
g protein-coupled receptor
gpcr
agonist
arrestin
conformational dynamics
phosphorylation
phosphorylation barcode
receptor signaling
single-molecule fret
β-arrestin
Publication Type:
Article
Unique ID:
10.1016/j.cell.2022.03.042
PMID:
Journal:
Publication Date:
Data Source:
Scopus

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