Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors

Lagomarsino, V. N., Pearse, R. V., Liu, L., Hsieh, Y.-C., Fernandez, M. A., Vinton, E. A., Paull, D., Felsky, D., Tasaki, S., Gaiteri, C., Vardarajan, B., Lee, H., Muratore, C. R., Benoit, C. R., Chou, V., Fancher, S. B., He, A., Merchant, J. P., Duong, D. M., … Young-Pearse, T. L. (2021). Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors. Neuron, 109(21), 3402-3420.e9. https://doi.org/10.1016/j.neuron.2021.08.003
Authors:
Valentina N. Lagomarsino
Richard V. Pearse
Lei Liu
Yi-Chen Hsieh
Marty A. Fernandez
Elizabeth A. Vinton
Daniel Paull
Daniel Felsky
Shinya Tasaki
Chris Gaiteri
Badri Vardarajan
Hyo Lee
Christina R. Muratore
Courtney R. Benoit
Vicky Chou
Seeley B. Fancher
Amy He
Julie P. Merchant
Duc M. Duong
Hector Martinez
Monica Zhou
Fatmata Bah
Maria A. Vicent
Jonathan M.S. Stricker
Jishu Xu
Eric B. Dammer
Allan I. Levey
Lori B. Chibnik
Vilas Menon
Nicholas T. Seyfried
Philip L. De Jager
Scott Noggle
Dennis J. Selkoe
David A. Bennett
Tracy L. Young-Pearse
Affiliated Authors:
Badri Vardarajan
Vilas Menon
Philip L. De Jager
Columbia Affiliation:
Author Keywords:
alzheimer's
aβ
genetics
ipsc
load
mapt
neuron
pp1
prs
tau
elink
Publication Type:
Article
Unique ID:
10.1016/j.neuron.2021.08.003
PMID:
34473944
DOI:
10.1016/j.neuron.2021.08.003
Journal:
Neuron
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
View Web of Science Record

Record Created: