Results of SIGNAL‐AD, a randomized, phase 1b/2 trial to evaluate safety and efficacy of targeting reactive astrocytes with pepinemab, SEMA4D blocking antibody, in people with mild Alzheimer’s dementia

Siemers, E. R., Evans, E. E., Fisher, T. L., Boise, M., Foster, A., Leonard, J. E., Mishra, V., Mallow, C. L., Porsteinsson, A. P., Turner, R. S., Bond, W., Huffaker, J., Farlow, M. R., Honig, L. S., Sheldon, E., Townley, R. A., Winner, P., Norton, J., Holub, R., … Zauderer, M. (2024). Results of SIGNAL‐AD, a randomized, phase 1b/2 trial to evaluate safety and efficacy of targeting reactive astrocytes with pepinemab, SEMA4D blocking antibody, in people with mild Alzheimer’s dementia. Alzheimer’s & Dementia, 20(S2). Portico. https://doi.org/10.1002/alz.092538
Authors:
Eric Siemers
Elizabeth E. Evans
Terrence L. Fisher
Megan Boise
Amber Foster
John E. Leonard
Vikas Mishra
Crystal Mallow
Anton P. Porsteinsson
Raymond Scott Turner
Wendy Bond
John Huffaker
Martin R. Farlow
Lawrence S. Honig
Elizabeth Sheldon
Ryan Townley
Paul Winner
Jeffrey A. Norton
Richard Holub
Paayal Patel
David Geldmacher
Horacio Capote
Stephen Thein
Maurice Zauderer
Affiliated Authors:
Lawrence S. Honig
Publication Type:
Article
Unique ID:
10.1002/alz.092538
Publication Date:
Data Source:
OpenAlex

Record Created: