Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

de Vries, L. E., Jansen, P. A. M., Barcelo, C., Munro, J., Verhoef, J. M. J., Pasaje, C. F. A., Rubiano, K., Striepen, J., Abla, N., Berning, L., Bolscher, J. M., Demarta-Gatsi, C., Henderson, R. W. M., Huijs, T., Koolen, K. M. J., Tumwebaze, P. K., Yeo, T., Aguiar, A. C. C., Angulo-Barturen, I., … Dechering, K. J. (2022). Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-29688-5
Authors:
Laura E. de Vries
Patrick A. M. Jansen
Catalina Barcelo
Justin Munro
Julie M. J. Verhoef
Charisse Flerida A. Pasaje
Kelly Rubiano
Josefine Striepen
Nada Abla
Luuk Berning
Judith M. Bolscher
Claudia Demarta-Gatsi
Rob W. M. Henderson
Tonnie Huijs
Karin M. J. Koolen
Patrick K. Tumwebaze
Tomas Yeo
Anna C. C. Aguiar
Iñigo Angulo-Barturen
Alisje Churchyard
Jake Baum
Benigno Crespo Fernández
Aline Fuchs
Francisco-Javier Gamo
Rafael V. C. Guido
María Belén Jiménez-Diaz
Dhelio B. Pereira
Rosemary Rochford
Camille Roesch
Laura M. Sanz
Graham Trevitt
Benoit Witkowski
Sergio Wittlin
Roland A. Cooper
Philip J. Rosenthal
Robert W. Sauerwein
Joost Schalkwijk
Pedro H. H. Hermkens
Roger V. Bonnert
Brice Campo
David A. Fidock
Manuel Llinás
Jacquin C. Niles
Taco W. A. Kooij
Koen J. Dechering
Affiliated Authors:
Kelly Rubiano
Josefine Striepen
Tomas Yeo
David A. Fidock
Columbia Affiliation:
Subjects:
Antimalarials (MeSH)
Folic Acid Antagonists (MeSH)
Malaria (MeSH)
Malaria, Falciparum (MeSH)
Malaria, Vivax (MeSH)
Neurodegeneration with Brain Iron Accumulation (OpenAlex Topic)
Nucleotide Metabolism and Enzyme Regulation (OpenAlex Topic)
Chemical Synthesis and Analysis (OpenAlex Topic)
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Publication Type:
Article
Unique ID:
10.1038/s41467-022-29688-5
PMID:
35444200
DOI:
10.1038/s41467-022-29688-5
Journal:
Nature Communications
Publication Date:
Data Source:
Scopus
Source Link:
View Scopus Record
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