Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target

Istvan, E. S., Guerra, F., Abraham, M., Huang, K.-S., Rocamora, F., Zhao, H., Xu, L., Pasaje, C., Kumpornsin, K., Luth, M. R., Cui, H., Yang, T., Palomo Diaz, S., Gomez-Lorenzo, M. G., Qahash, T., Mittal, N., Ottilie, S., Niles, J., Lee, M. C. S., … Winzeler, E. A. (2023). Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target. Science Translational Medicine, 15(686). https://doi.org/10.1126/scitranslmed.adc9249
Authors:
Eva S. Istvan
Francisco Guerra
Matthew Abraham
Kuo‐Sen Huang
Frances Rocamora
Haoshuang Zhao
Lan Xu
Charisse Flerida A. Pasaje
Krittikorn Kümpornsin
Madeline R. Luth
Haissi Cui
Tuo Yang
Sara Palomo Dı́az
Marı́a G. Gómez-Lorenzo
Tarrick Qahash
Nimisha Mittal
Sabine Ottilie
Jacquin C. Niles
Lee M
Manuel Llinás
Nobutaka Kato
John Okombo
David A. Fidock
Paul Schimmel
Francisco‐Javier Gamo
Daniel E. Goldberg
Elizabeth A. Winzeler
Affiliated Authors:
John Okombo
David A. Fidock
Columbia Affiliation:
Subjects:
Antimalarials (MeSH)
Malaria, Falciparum (MeSH)
Malaria (MeSH)
Ribosome Structure and Translation Mechanisms (OpenAlex Topic)
Global Challenge of Antibiotic Resistance in Bacteria (OpenAlex Topic)
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Publication Type:
Article
Unique ID:
10.1126/scitranslmed.adc9249
PMID:
36888694
DOI:
10.1126/scitranslmed.adc9249
Journal:
Science Translational Medicine
Publication Date:
Data Source:
OpenAlex
Source Link:
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