Gliovascular transcriptional perturbations in Alzheimer’s disease reveal molecular mechanisms of blood brain barrier dysfunction

İş, Ö., Wang, X., Reddy, J. S., Min, Y., Yilmaz, E., Bhattarai, P., Patel, T., Bergman, J., Quicksall, Z., Heckman, M. G., Tutor-New, F. Q., Can Demirdogen, B., White, L., Koga, S., Krause, V., Inoue, Y., Kanekiyo, T., Cosacak, M. I., Nelson, N., … Ertekin-Taner, N. (2024). Gliovascular transcriptional perturbations in Alzheimer’s disease reveal molecular mechanisms of blood brain barrier dysfunction. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-48926-6
Authors:
Özkan İş
Xue Wang
Joseph S. Reddy
Yuhao Min
Elanur Yılmaz
Prabesh Bhattarai
Tulsi Patel
Jeremiah Bergman
Zachary Quicksall
Michael G. Heckman
Frederick Q. Tutor‐New
Birsen Can Demirdöğen
Launia J. White
Shunsuke Koga
Vanessa Krause
Yasuteru Inoue
Takahisa Kanekiyo
Mehmet İlyas Coşacak
Nastasia Nelson
Annie Lee
Badri N. Vardarajan
Richard Mayeux
Naomi Kouri
Kaancan Deniz
Troy Carnwath
Stephanie R. Oatman
Laura J. Lewis‐Tuffin
Thuy Nguyen
Minerva M. Carrasquillo
Jonathan Graff‐Radford
Ronald C. Petersen
Clifford R. Jack
Kejal Kantarci
Melissa E. Murray
Kwangsik Nho
Andrew J. Saykin
Dennis W. Dickson
Çağhan Kızıl
Mariet Allen
Nilüfer Ertekin‐Taner
Affiliated Authors:
Elanur Yılmaz
Prabesh Bhattarai
Nastasia Nelson
Annie Lee
Badri N. Vardarajan
Richard Mayeux
Çağhan Kızıl
Columbia Affiliation:
Subjects:
Alzheimer Disease (MeSH)
Blood-Brain Barrier (MeSH)
Smad3 Protein (MeSH)
Zebrafish (MeSH)
Astrocytes (MeSH)
Vascular Endothelial Growth Factor A (MeSH)
Pericytes (MeSH)
Blood-Brain Barrier and Neurovascular Interactions (OpenAlex Topic)
Comprehensive Integration of Single-Cell Transcriptomic Data (OpenAlex Topic)
Epigenetic Modifications and Their Functional Implications (OpenAlex Topic)
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Publication Type:
Article
Unique ID:
10.1038/s41467-024-48926-6
PMID:
38902234
DOI:
10.1038/s41467-024-48926-6
Journal:
Nature Communications
Publication Date:
Data Source:
OpenAlex
Source Link:
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