Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis

Jiang, Z., Wu, F., Laise, P., Takayuki, T., Na, F., Kim, W., Kobayashi, H., Chang, W., Takahashi, R., Valenti, G., Sunagawa, M., White, R. A., Macchini, M., Renz, B. W., Middelhoff, M., Hayakawa, Y., Dubeykovskaya, Z. A., Tan, X., Chu, T. H., … Wang, T. C. (2023). Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis. Cell Stem Cell, 30(8), 1091-1109.e7. https://doi.org/10.1016/j.stem.2023.07.002
Authors:
Zhengyu Jiang
Feijing Wu
Pasquale Laise
Tanaka Takayuki
Fu Na
Woosook Kim
Hiroki Kobayashi
Wenju Chang
Ryota Takahashi
Giovanni Valenti
Masaki Sunagawa
Ruth A White
Marina Macchini
Bernhard W Renz
Moritz Middelhoff
Yoku Hayakawa
Zinaida A Dubeykovskaya
Xiangtian Tan
Timothy H Chu
Karan Nagar
Yagnesh Tailor
Bryana R Belin
Akanksha Anand
Samuel Asfaha
Michael O Finlayson
Alina C Iuga
Andrea Califano
Timothy C Wang
Affiliated Authors:
Zhengyu Jiang
Feijing Wu
Pasquale Laise
Tanaka Takayuki
Fu Na
Woosook Kim
Hiroki Kobayashi
Wenju Chang
Ryota Takahashi
Giovanni Valenti
Masaki Sunagawa
Ruth A White
Marina Macchini
Bernhard W Renz
Moritz Middelhoff
Zinaida A Dubeykovskaya
Xiangtian Tan
Timothy H Chu
Karan Nagar
Yagnesh Tailor
Bryana R Belin
Michael O Finlayson
Alina C Iuga
Andrea Califano
Timothy C Wang
Columbia Affiliation:
Subjects:
Pancreatic Neoplasms (MeSH)
Carcinoma, Pancreatic Ductal (MeSH)
Author Keywords:
cell ablation
lineage tracing
pancreas
pancreatic ductal carcinoma
progenitor cells
regeneration
transit-amplifying cells
trefoil factor 2
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Publication Type:
Article
Unique ID:
10.1016/j.stem.2023.07.002
PMID:
37541213
DOI:
10.1016/j.stem.2023.07.002
Journal:
Cell Stem Cell
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
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Record Created: