Interaction of an α-synuclein epitope with HLA-DRB1∗15:01 triggers enteric features in mice reminiscent of prodromal Parkinson’s disease

Garretti, F., Monahan, C., Sloan, N., Bergen, J., Shahriar, S., Kim, S. W., Sette, A., Cutforth, T., Kanter, E., Agalliu, D., & Sulzer, D. (2023). Interaction of an α-synuclein epitope with HLA-DRB1∗15:01 triggers enteric features in mice reminiscent of prodromal Parkinson’s disease. Neuron, 111(21), 3397-3413.e5. https://doi.org/10.1016/j.neuron.2023.07.015
Authors:
Francesca Garretti
Connor Monahan
Nicholas Sloan
Jeroen van Bergen
Sanjid Shahriar
Seon Woo Kim
Alessandro Sette
Tyler Cutforth
Ellen Kanter
Dritan Agalliu
David Sulzer
Affiliated Authors:
Francesca Garretti
Connor Monahan
Nicholas Sloan
Jeroen van Bergen
Sanjid Shahriar
Tyler Cutforth
Ellen Kanter
Dritan Agalliu
David Sulzer
Columbia Affiliation:
Subjects:
Parkinson Disease (MeSH)
Pathophysiology of Parkinson's Disease (OpenAlex Topic)
Functional Bowel Disorders and Gastrointestinal Health (OpenAlex Topic)
Feeding Disorders in Children with Autism Spectrum Disorders (OpenAlex Topic)
Author Keywords:
antigen-experienced trm
cd4+ t cells
constipation
enteric dopaminergic neurons
hla-drb1∗15:01
mucosal barriers
neo-antigen
parkinson's disease
prodromal disease
α-synuclein
cd4(+) t cells
hla-drb1(∗)15:01
parkinson’s disease
antigen-experienced t(rm)
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Publication Type:
Article
Unique ID:
10.1016/j.neuron.2023.07.015
PMID:
37597517
DOI:
10.1016/j.neuron.2023.07.015
Journal:
Neuron
Publication Date:
Data Source:
OpenAlex
Source Link:
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