Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

Upadhyayula, P. S., Higgins, D. M., Mela, A., Banu, M., Dovas, A., Zandkarimi, F., Patel, P., Mahajan, A., Humala, N., Nguyen, T. T. T., Chaudhary, K. R., Liao, L., Argenziano, M., Sudhakar, T., Sperring, C. P., Shapiro, B. L., Ahmed, E. R., Kinslow, C., Ye, L. F., … Canoll, P. (2023). Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-36630-w
Authors:
Pavan S. Upadhyayula
Dominique M. Higgins
Angeliki Mela
Matei Banu
Athanassios Dovas
Fereshteh Zandkarimi
Purvi Patel
Aayushi Mahajan
Nelson Humala
Trang T. T. Nguyen
Kunal R. Chaudhary
Lillian Liao
Michael Argenziano
Tejaswi Sudhakar
Colin P. Sperring
Benjamin L. Shapiro
Eman R. Ahmed
Connor Kinslow
Ling F. Ye
Markus D. Siegelin
Simon Cheng
Rajesh Soni
Jeffrey N. Bruce
Brent R. Stockwell
Peter Canoll
Affiliated Authors:
Pavan S. Upadhyayula
Dominique M. Higgins
Angeliki Mela
Matei Banu
Athanassios Dovas
Purvi Patel
Aayushi Mahajan
Nelson Humala
Trang T. T. Nguyen
Kunal R. Chaudhary
Lillian Liao
Michael Argenziano
Tejaswi Sudhakar
Colin P. Sperring
Benjamin L. Shapiro
Eman R. Ahmed
Ling F. Ye
Markus D. Siegelin
Rajesh Soni
Jeffrey N. Bruce
Brent R. Stockwell
Peter Canoll
Columbia Affiliation:
Subjects:
Ferroptosis (MeSH)
Glioma (MeSH)
Mechanisms and Implications of Ferroptosis in Cancer (OpenAlex Topic)
Lipid Metabolism in Cancer Pathogenesis (OpenAlex Topic)
Epigenetic Modifications and Their Functional Implications (OpenAlex Topic)
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Publication Type:
Article
Unique ID:
10.1038/s41467-023-36630-w
PMID:
36864031
DOI:
10.1038/s41467-023-36630-w
Journal:
Nature Communications
Publication Date:
Data Source:
Scopus
Source Link:
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