R01AG049810

NIH – National Institute On Aging

Approaches to timescale choice in cognitive aging research and potential implications for estimated exposure effects: coordinated analyses in ten cohorts of older adults

Hayes-Larson, E., Andrews, R. M., Kezios, K. L., Bercu, A., Rouanet, A., Helmer, C., Crane, P. K., Gibbons, L., Klinedinst, B. S., McEvoy, L. K., Nichols, E., Weuve, J., Rajan, K. B., Hwang, P. H., Mez, J., Farina, M., Shaw, C., Sims, K. D., Therneau, T., … Mayeda, E. R. (2025). Approaches to timescale choice in cognitive aging research and potential implications for estimated exposure effects: coordinated analyses in ten cohorts of older adults. Epidemiology. https://doi.org/10.1097/ede.0000000000001859
Authors:
Eleanor Hayes-Larson
Ryan M Andrews
Katrina L Kezios
Ariane Bercu
Anaïs Rouanet
Catherine Helmer
Paul K Crane
Laura Gibbons
Brandon S Klinedinst
Linda K McEvoy
Emma Nichols
Jennifer Weuve
Kumar B Rajan
Phillip H Hwang
Jesse Mez
Mateo Farina
Crystal Shaw
Kendra D Sims
Terry Therneau
Ronald C Petersen
Vincent Bouteloup
Alden Gross
Marilyn Albert
John C Morris
Colin L Masters
Susan M Resnick
Paul Maruff
Jennifer J Manly
Indira Turney
Jet M J Vonk
Justina Avila-Rieger
Alexandra Weigand
Ruijia Chen
Jingxuan Wang
Cécile Proust-Lima
Elizabeth Rose Mayeda
Affiliated Authors:
Katrina L Kezios
Jennifer J Manly
Indira Turney
Justina Avila-Rieger
Author Keywords:
apolipoprotein e
cognitive change
cognitive decline
diabetes
linear mixed-effects models
longitudinal analysis
timescale
apolipoprotein e4
african american
aged
article
caucasian
cognitive aging
cognitive defect
cohort analysis
controlled study
diabetes mellitus
disease association
educational status
episodic memory
female
follow up
genotype
hispanic
human
major clinical study
male
medical decision making
medical research
memory
memory assessment
aging
epidemiology
genetics
physiology
time factor
very elderly
aged, 80 and over
cohort studies
humans
time factors
Grants:
F31AG071191 (NIH – National Institute on Aging)
F99AG083306 (NIH – National Institute On Aging)
K00AG068431 (NIH – National Institute On Aging)
K01AG080119 (NIH – National Institute on Aging)
K99AG075317 (NIH – National Institute On Aging)
K99AG076975 (NIH – National Institute On Aging)
K99AG078440 (NIH – National Institute On Aging)
K99AG083121 (NIH – National Institute On Aging)
K99AG084769 (NIH – National Institute on Aging)
P01AG003991 (NIH – National Institute On Aging)
P01AG007232 (NIH – National Institute on Aging)
P01AG026276 (NIH – National Institute On Aging)
P30AG059303 (NIH – National Institute On Aging)
P30AG066444 (NIH – National Institute On Aging)
P30AG066509 (NIH – National Institute On Aging)
P30AG072978 (NIH – National Institute On Aging)
P50AG005136 (NIH – National Institute On Aging)
R00AG066934 (NIH – National Institute On Aging)
R00AG075317 (NIH – National Institute on Aging)
R00AG078440 (NIH – National Institute on Aging)
R00AG084769 (NIH – National Institute on Aging)
R01AG008122 (NIH – National Institute On Aging)
R01AG011101 (NIH – National Institute On Aging)
R01AG027161 (NIH – National Institute on Aging)
R01AG030153 (NIH – National Institute On Aging)
R01AG037212 (NIH – National Institute On Aging)
R01AG049810 (NIH – National Institute On Aging)
R01AG058679 (NIH – National Institute on Aging)
R01AG061028 (NIH – National Institute on Aging)
R01AG062109 (NIH – National Institute on Aging)
R01AG065359 (NIH – National Institute On Aging)
R01AG070953 (NIH – National Institute On Aging)
R01AG072474 (NIH – National Institute On Aging)
R01AG072681 (NIH – National Institute On Aging)
R01AG073627 (NIH – National Institute on Aging)
R13AG064971 (NIH – National Institute On Aging)
RF1AG027161 (NIH – National Institute on Aging)
RF1AG054023 (NIH – National Institute On Aging)
RF1AG054156 (NIH – National Institute On Aging)
RF1AG059869 (NIH – National Institute on Aging)
RF1AG062109 (NIH – National Institute On Aging)
U01AG006781 (NIH – National Institute On Aging)
U01AG006786 (NIH – National Institute On Aging)
U01AG009740 (NIH – National Institute On Aging)
U01AG033655 (NIH – National Institute on Aging)
U01HL096812 (NIH – National Heart, Lung, and Blood Institute)
U01HL096814 (NIH – National Heart, Lung, and Blood Institute)
U01HL096899 (NIH – National Heart, Lung, and Blood Institute)
U01HL096902 (NIH – National Heart, Lung, and Blood Institute)
U01HL096917 (NIH – National Heart, Lung, and Blood Institute)
U19AG033655 (NIH – National Institute On Aging)
U19AG066567 (NIH – National Institute On Aging)
U19AG068753 (NIH – National Institute On Aging)
U24AG074855 (NIH – National Institute On Aging)
UH2AG083289 (NIH – National Institute on Aging)
UL1TR001873 (NIH – National Center for Advancing Translational Sciences)
Publication Type:
Article
Unique ID:
10.1097/ede.0000000000001859
PMID:
Journal:
Publication Date:
Data Source:
PubMed

Record Created:

Long-term blood pressure patterns in midlife and dementia in later life: Findings from the Framingham Heart Study

Kim, H., Ang, T. F. A., Thomas, R. J., Lyons, M. J., & Au, R. (2023). Long‐term blood pressure patterns in midlife and dementia in later life: Findings from the Framingham Heart Study. Alzheimer’s & Dementia, 19(10), 4357–4366. Portico. https://doi.org/10.1002/alz.13356
Authors:
Hyun Kim
Ting Fang Alvin Ang
Robert J. Thomas
Michael J. Lyons
Rhoda Au
Affiliated Authors:
Hyun Kim
Rhoda Au
Author Keywords:
blood pressure
dementia
midlife
prevention
Grants:
R01NS017950 (NIH – National Institute of Neurological Disorders and Stroke)
R01AG008122 (NIH – National Institute On Aging)
R01AG016495 (NIH – National Institute On Aging)
RF1AG062109 (NIH – National Institute On Aging)
R01AG054076 (NIH – National Institute On Aging)
U19AG068753 (NIH – National Institute On Aging)
R56AG062109 (NIH – National Institute On Aging)
R01AG049810 (NIH – National Institute On Aging)
Publication Type:
Article
Unique ID:
10.1002/alz.13356
PMID:
Publication Date:
Data Source:
Scopus

Record Created:

Increased regional white matter hyperintensity volume in objectively-defined subtle cognitive decline and mild cognitive impairment

Calcetas, A. T., Thomas, K. R., Edmonds, E. C., Holmqvist, S. L., Edwards, L., Bordyug, M., Delano-Wood, L., Brickman, A. M., Bondi, M. W., Bangen, K. J., & for the Alzheimer’s Disease Neuroimaging Initiative. (2022). Increased regional white matter hyperintensity volume in objectively-defined subtle cognitive decline and mild cognitive impairment. Neurobiology of Aging, 118, 1–8. https://doi.org/10.1016/j.neurobiolaging.2022.06.002
Authors:
Amanda T. Calcetas
Kelsey R. Thomas
Emily C. Edmonds
Sophia L. Holmqvist
Lauren Edwards
Maria Bordyug
Lisa Delano-Wood
Adam M. Brickman
Mark W. Bondi
Katherine J. Bangen
for the Alzheimer's Disease Neuroimaging Initiative
Affiliated Authors:
Adam M. Brickman
Author Keywords:
white matter hyperintensities
preclinical alzheimer?s disease
subtle cognitive decline
magnetic resonance imaging
cerebrovascular disease
preclinical alzheimer's disease
Grants:
R03AG070435 (NIH – National Institute On Aging)
P30AG062429 (NIH – National Institute On Aging)
U01AG024904 (NIH – National Institute On Aging)
R01AG049810 (NIH – National Institute On Aging)
R01AG063782 (NIH – National Institute On Aging)
IK2CX001415 (NIH – Veterans Affairs)
I01CX001842 (NIH – Veterans Affairs)
IK2CX001865 (NIH – Veterans Affairs)
Publication Type:
Article
Unique ID:
10.1016/j.neurobiolaging.2022.06.002
PMID:
Publication Date:
Data Source:
Scopus

Record Created: