I01CX001849

NIH – Veterans Affairs

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Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference

Meng, X., Navoly, G., Giannakopoulou, O., Levey, D. F., Koller, D., Pathak, G. A., Koen, N., Lin, K., Adams, M. J., Rentería, M. E., Feng, Y., Gaziano, J. M., Stein, D. J., Zar, H. J., Campbell, M. L., van Heel, D. A., Trivedi, B., Finer, S., … McQuillin, A. (2024). Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference. Nature Genetics, 56(2), 222–233. https://doi.org/10.1038/s41588-023-01596-4
Authors:
Xiangrui Meng
Georgina Navoly
Olga Giannakopoulou
Daniel F Levey
Dora Koller
Gita A Pathak
Nastassja Koen
Kuang Lin
Mark J Adams
Miguel E Rentería
Yanzhe Feng
J Michael Gaziano
Dan J Stein
Heather J Zar
Megan L Campbell
David A van Heel
Bhavi Trivedi
Sarah Finer
Andrew McQuillin
Nick Bass
V Kartik Chundru
Hilary C Martin
Qin Qin Huang
Maria Valkovskaya
Chia-Yi Chu
Susan Kanjira
Po-Hsiu Kuo
Hsi-Chung Chen
Shih-Jen Tsai
Yu-Li Liu
Kenneth S Kendler
Roseann E Peterson
Na Cai
Yu Fang
Srijan Sen
Laura J Scott
Margit Burmeister
Ruth J F Loos
Michael H Preuss
Ky'Era V Actkins
Lea K Davis
Monica Uddin
Agaz H Wani
Derek E Wildman
Allison E Aiello
Robert J Ursano
Ronald C Kessler
Masahiro Kanai
Yukinori Okada
Saori Sakaue
Jill A Rabinowitz
Brion S Maher
George Uhl
William Eaton
Carlos S Cruz-Fuentes
Gabriela A Martinez-Levy
Adrian I Campos
Iona Y Millwood
Zhengming Chen
Liming Li
Sylvia Wassertheil-Smoller
Yunxuan Jiang
Chao Tian
Nicholas G Martin
Brittany L Mitchell
Enda M Byrne
Swapnil Awasthi
Jonathan R I Coleman
Stephan Ripke
Tamar Sofer
Robin G Walters
Andrew M McIntosh
Renato Polimanti
Erin C Dunn
Murray B Stein
Joel Gelernter
Cathryn M Lewis
Karoline Kuchenbaecker
Affiliated Authors:
Allison E Aiello
Columbia Affiliation:
Subjects:
Genome-Wide Association Study (MeSH)
Depressive Disorder, Major (MeSH)
Grants:
R01HD074711 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
UL1TR001863 (NIH – National Center for Advancing Translational Sciences)
UL1TR002243 (NIH – National Center for Advancing Translational Sciences)
UL1TR000445 (NIH – National Center for Advancing Translational Sciences)
UL1RR024975 (NIH – National Center for Research Resources)
U19HL065962 (NIH – National Heart, Lung, and Blood Institute)
U01HL065233 (NIH – National Heart, Lung, and Blood Institute)
U01HG004798 (NIH – National Human Genome Research Institute)
U01HG006378 (NIH – National Human Genome Research Institute)
P50GM115305 (NIH – National Institute of General Medical Sciences)
RC2GM092618 (NIH – National Institute of General Medical Sciences)
T32MH014276 (NIH – National Institute of Mental Health)
R01MH101459 (NIH – National Institute of Mental Health)
R01MH100549 (NIH – National Institute of Mental Health)
R01MH125938 (NIH – National Institute of Mental Health)
R01MH113930 (NIH – National Institute of Mental Health)
R21MH126358 (NIH – National Institute of Mental Health)
R01MH124873 (NIH – National Institute of Mental Health)
R01NS032830 (NIH – National Institute of Neurological Disorders and Stroke)
R21DC018098 (NIH – National Institute On Deafness and Other Communication Disorders)
R01DA009897 (NIH – National Institute On Drug Abuse)
R33DA047527 (NIH – National Institute On Drug Abuse)
R01MD011728 (NIH – National Institute On Minority Health and Health Disparities)
I01CX001849 (NIH – Veterans Affairs)
Publication Type:
Article
Unique ID:
10.1038/s41588-023-01596-4
PMID:
38177345
DOI:
10.1038/s41588-023-01596-4
Journal:
Nature Genetics
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record
View Web of Science Record

Record Created:

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