Cyclooxygenase-2 Inhibitors in Inflammation and Cancer

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Paiola, M., Portnoy, D. M., Hao, L. Y., Bukhari, S., Winchester, R. J., Henick, B. S., Mor, A., & Gartshteyn, Y. (2025). Osteoarthritis increases the risk of inflammatory arthritis due to immune checkpoint inhibitors associated with tissue-resident memory T cells. Journal for ImmunoTherapy of Cancer, 13(3), e010758. https://doi.org/10.1136/jitc-2024-010758
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Schoenfeld, A. J., Izar, B., Spira, A., Zamarin, D., Spigel, D. R., Hoimes, C., McDermott, D. F., Sehgal, K., Najjar, Y. G., Garon, E. B., Sullivan, R. J., Henick, B., Leal, T. A., Hurwitz, M., McKay, R., Gong, X., Rokade, S., Stager, A. M., Bach, K., … Oft, M. (2024). 1325 T cell and immune activation from a phase 1 study of STK-012, a first-in-class IL-2R α/β selective partial agonist in advanced solid tumors. Regular and Young Investigator Award Abstracts, A1484–A1484. https://doi.org/10.1136/jitc-2024-sitc2024.1325
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Markosyan, N., Kim, I.-K., Arora, C., Quinones-Ware, L., Joshi, N., Cheng, N., Schechter, E. Y., Tobias, J. W., Hochberg, J. E., Corse, E., Liu, K., Rodriguez DiBlasi, V., Chan, L.-C. (Eric), Smyth, E. M., FitzGerald, G. A., Stanger, B. Z., & Vonderheide, R. H. (2024). Pivotal roles for cancer cell–intrinsic mPGES-1 and autocrine EP4 signaling in suppressing antitumor immunity. JCI Insight, 9(21). https://doi.org/10.1172/jci.insight.178644
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Rossano, S., Talmasov, D., Johnson, A. S., Smith, A. C., Guzmán, D. S., Okafor, A., Kreisl, W. C., De Jager, P. L., & Lao, P. J. (2023). Validating noninvasive techniques for 11C‐ER176 PET quantification in controls and Alzheimer’s disease patients. Alzheimer’s & Dementia, 19(S10). Portico. https://doi.org/10.1002/alz.081801
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Rossano, S., Talmasov, D., Johnson, A. S., Smith, A. C., Guzmán, D. S., Okafor, A., Kreisl, W. C., De Jager, P. L., & Lao, P. J. (2023). Validating noninvasive techniques for 11C‐ER176 PET quantification in controls and Alzheimer’s disease patients. Alzheimer’s & Dementia, 19(S17). Portico. https://doi.org/10.1002/alz.078290
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