Calcineurin-NFAT Signaling in Transcriptional Regulation

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Unique ID
https://openalex.org/T12620

Antibodies targeting ADAM17 reverse neurite outgrowth inhibition by myelin-associated inhibitors

Saha, N., Chan, E., Mendoza, R. P., Romin, Y., Tipping, M. J., & Nikolov, D. B. (2025). Antibodies targeting ADAM17 reverse neurite outgrowth inhibition by myelin-associated inhibitors. Life Science Alliance, 8(6), e202403126. https://doi.org/10.26508/lsa.202403126
Authors:
Nayanendu Saha
Eric Chan
Rachelle P Mendoza
Yevgeniy Romin
Murray J Tipping
Dimitar B Nikolov
Affiliated Authors:
Rachelle P Mendoza
Author Keywords:
adam10 endopeptidase
tumor necrosis factor alpha converting enzyme
adam10 protein
adam17 protein
adam17 protein, human
amyloid precursor protein secretases
antibodies, monoclonal
lingo1 protein, human
membrane proteins
myelin proteins
myelin-associated glycoprotein
nerve tissue proteins
nogo proteins
membrane protein
monoclonal antibody
myelin associated glycoprotein
myelin protein
nerve protein
protein nogo
secretase
animal
drug effect
human
immunology
metabolism
mouse
myelin sheath
nerve cell
neurite
neurite outgrowth
signal transduction
spinal cord injury
tumor cell line
animals
cell line, tumor
humans
mice
neurites
neuronal outgrowth
neurons
spinal cord injuries
Publication Type:
Article
Unique ID:
10.26508/lsa.202403126
PMID:
Publication Date:
Data Source:
PubMed

Record Created:

Activating Transcription Factor 5 (ATF5) Promotes Neuroblastoma Metastasis by Inducing Anoikis Resistance

Banerjee, D., Boboila, S., Okochi, S., Angelastro, J. M., Kadenhe-Chiweshe, A. V., Lopez, G., Califano, A., Connolly, E. P., Greene, L. A., & Yamashiro, D. J. (2023). Activating Transcription Factor 5 Promotes Neuroblastoma Metastasis by Inducing Anoikis Resistance. Cancer Research Communications, 3(12), 2518–2530. https://doi.org/10.1158/2767-9764.crc-23-0154
Authors:
Debarshi Banerjee
Shuobo Boboila
Shunpei Okochi
James M. Angelastro
Angela V. Kadenhe‐Chiweshe
Gonzalo López
Andrea Califano
Eileen P. Connolly
Lloyd A. Greene
Darrell J. Yamashiro
Affiliated Authors:
Debarshi Banerjee
Shuobo Boboila
Shunpei Okochi
Gonzalo López
Andrea Califano
Eileen P. Connolly
Lloyd A. Greene
Darrell J. Yamashiro
Grants:
P30CA013696 (NIH – National Cancer Institute)
R35CA197745 (NIH – National Cancer Institute)
U01CA272610 (NIH – National Cancer Institute)
S10OD021764 (NIH – Office of the Director, National Institutes of Health)
S10OD012351 (NIH – Office of the Director, National Institutes of Health)
Publication Type:
Article
Unique ID:
10.1158/2767-9764.crc-23-0154
PMID:
Publication Date:
Data Source:
OpenAlex

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P-200 MAP4K2 inhibition reinforces sensitivity to iberdomide in RAS-mutated MM through a CRBN-independent mechanism

Li, S., Fu, J., Liu, G., Ma, H., Mapara, M., Marcireau, C., & Lentzsch, S. (2023). P-200 MAP4K2 inhibition reinforces sensitivity to iberdomide in RAS-mutated MM through a CRBN-independent mechanism. Clinical Lymphoma Myeloma and Leukemia, 23, S145–S146. https://doi.org/10.1016/s2152-2650(23)01818-9
Authors:
Shirong Li
Jing Fu
Guifen Liu
Huihui Ma
Markus Y. Mapara
Christophe Marcireau
Suzanne Lentzsch
Affiliated Authors:
Shirong Li
Jing Fu
Guifen Liu
Huihui Ma
Suzanne Lentzsch
Publication Type:
Article
Unique ID:
10.1016/s2152-2650(23)01818-9
Publication Date:
Data Source:
OpenAlex

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Abrogation of MAP4K4 protein function causes congenital anomalies in humans and zebrafish

Patterson, V., Ullah, F., Bryant, L., Li, D., Griffin, J. N., Sidhu, A., Saliganan, S., Blaile, M., Saenz, M. S., Smith, R., Ellingwood, S., Grange, D. K., Hu, X., Mireguli, M., Luo, Y., Shen, Y., Mulhern, M., Zackai, E., Ritter, A., … Bhoj, E. (2023). Abrogation of MAP4K4 protein function causes congenital anomalies in humans and zebrafish. Science Advances, 9(17). https://doi.org/10.1126/sciadv.ade0631
Authors:
Victoria Patterson
Farid Ullah
Laura Bryant
John N Griffin
Alpa Sidhu
Sheila Saliganan
Mackenzie Blaile
Margarita S Saenz
Rosemarie Smith
Sara Ellingwood
Dorothy K Grange
Xuyun Hu
Maimaiti Mireguli
Yanfei Luo
Yiping Shen
Maureen Mulhern
Elaine Zackai
Alyssa Ritter
Kosaki Izumi
Julia Hoefele
Matias Wagner
Korbinian M Riedhammer
Barbara Seitz
Nathaniel H Robin
Dana Goodloe
Cyril Mignot
Boris Keren
Helen Cox
Joanna Jarvis
Maja Hempel
Cynthia Forster Gibson
Frederic Tran Mau-Them
Antonio Vitobello
Ange-Line Bruel
Arthur Sorlin
Sarju Mehta
F Lucy Raymond
Kelly Gilmore
Bradford C Powell
Karen Weck
Chumei Li
Anneke T Vulto-van Silfhout
Thea Giacomini
Maria Margherita Mancardi
Andrea Accogli
Vincenzo Salpietro
Federico Zara
Neeta L Vora
Erica E Davis
Rebecca Burdine
Elizabeth Bhoj
Affiliated Authors:
Maureen Mulhern
Grants:
R01HD055651 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
R01HD105868 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
K23HD088742 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
R03HD092694 (NIH – Eunice Kennedy Shriver National Institute of Child Health & Human Development)
R21TR002770 (NIH – National Center for Advancing Translational Sciences)
UL1TR002553 (NIH – National Center for Advancing Translational Sciences)
U01HG006487 (NIH – National Human Genome Research Institute)
R01AR071486 (NIH – National Institute of Arthritis and Musculoskeletal and Skin Diseases)
R01GM086537 (NIH – National Institute of General Medical Sciences)
R01MH106826 (NIH – National Institute of Mental Health)
Publication Type:
Article
Unique ID:
10.1126/sciadv.ade0631
PMID:
Journal:
Publication Date:
Data Source:
PubMed

Record Created:

Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmodium falciparum

Kucharski, M., Wirjanata, G., Nayak, S., Boentoro, J., Dziekan, J. M., Assisi, C., van der Pluijm, R. W., Miotto, O., Mok, S., Dondorp, A. M., & Bozdech, Z. (2023). Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmodium falciparum. PLOS Pathogens, 19(1), e1011118. https://doi.org/10.1371/journal.ppat.1011118
Authors:
Michal Kucharski
Grennady Wirjanata
Sourav Nayak
Josephine Boentoro
Jerzy M. Dziekan
Christina Assisi
Rob W. van der Pluijm
Olivo Miotto
Sachel Mok
Arjen M. Dondorp
Zbynek Bozdech
Affiliated Authors:
Sachel Mok
Publication Type:
Article
Unique ID:
10.1371/journal.ppat.1011118
PMID:
Journal:
Publication Date:
Data Source:
OpenAlex

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The Immunoglobulin Superfamily Member Basigin Is Required for Complex Dendrite Formation in Drosophila

Shrestha, B. R., Burgos, A., & Grueber, W. B. (2021). The Immunoglobulin Superfamily Member Basigin Is Required for Complex Dendrite Formation in Drosophila. Frontiers in Cellular Neuroscience, 15. https://doi.org/10.3389/fncel.2021.739741
Authors:
Brikha R Shrestha
Anita Burgos
Wesley B Grueber
Affiliated Authors:
Brikha R Shrestha
Anita Burgos
Wesley B Grueber
Author Keywords:
basigin
dendrite morphogenesis
drosophila
dendritic arborization neurons
sensory neuron
dendrite-substrate interaction
Publication Type:
Article
Unique ID:
10.3389/fncel.2021.739741
PMID:
Publication Date:
Data Source:
PubMed

Record Created:

Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency

Ward, T., Tai, W., Morton, S., Impens, F., Van Damme, P., Van Haver, D., Timmerman, E., Venturini, G., Zhang, K., Jang, M. Y., Willcox, J. A. L., Haghighi, A., Gelb, B. D., Chung, W. K., Goldmuntz, E., Porter, G. A., Lifton, R. P., Brueckner, M., Yost, H. J., … Seidman, J. G. (2021). Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency. Circulation Research, 128(8), 1156–1169. https://doi.org/10.1161/circresaha.120.316966
Authors:
Tarsha Ward
Warren Tai
Sarah Morton
Gabriela Venturini
Min Young Jang
Jon A. L. Willcox
Alireza Haghighi
Joshua Gorham
Yuri Kim
Alexandre Pereira
Jason Homsy
Craig C. Benson
Steven R. DePalma
Christine Seidman
J. G. Seidman
Francis Impens
Delphi Van Haver
Evy Timmerman
Kris Gevaert
Petra Van Damme
Kehan Zhang
Christopher S. Chen
Bruce D. Gelb
Wendy K. Chung
Elizabeth Goldmuntz
George A. Porter
Richard P. Lifton
Martina Brueckner
H. Joseph Yost
Benoit G. Bruneau
Sylvia Varland
Thomas Arnesen
Affiliated Authors:
Wendy K. Chung
Author Keywords:
congenital heart defects
haploinsufficiency
induced pluripotent stem cells
proteins
proteomics
ribosomes
Grants:
UL1TR001863 (NIH – National Center for Advancing Translational Sciences)
U01HL153009 (NIH – National Heart, Lung, and Blood Institute)
K08HL150284 (NIH – National Heart, Lung, and Blood Institute)
U01HL098153 (NIH – National Heart, Lung, and Blood Institute)
U01HL098147 (NIH – National Heart, Lung, and Blood Institute)
UM1HL098123 (NIH – National Heart, Lung, and Blood Institute)
R01HL151257 (NIH – National Heart, Lung, and Blood Institute)
UM1HL098179 (NIH – National Heart, Lung, and Blood Institute)
Publication Type:
Article
Unique ID:
10.1161/CIRCRESAHA.120.316966
PMID:
Publication Date:
Data Source:
Web of Science

Record Created: