Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Displaying 1 - 9 of 9CSV
Anis, S., Weill, C., Ponger, P., Nassar, M., Reiner, J., Chorin, O., Parlar, S. C., Alcalay, R. N., Gan-Or, Z., Ezra, A., Saar, A., Thaler, A., Cohen, O. S., Zlotnik, Y., Benizri, S., Nitsan, Z., Djaldetti, R., Yahalom, G., Schlesinger, I., … Greenbaum, L. (2025). Genetic testing for Parkinson’s disease in Israel: Insights from the Rostock Parkinson’s Disease (ROPAD) study. Parkinsonism & Related Disorders, 137, 107940. https://doi.org/10.1016/j.parkreldis.2025.107940
Publication Date
Goldstein, O., Shani, S., Gana-Weisz, M., Elkoshi, N., Casey, F., Sun, Y. H., Chandratre, K., Cedarbaum, J. M., Blauwendraat, C., Bar-Shira, A., Thaler, A., Gurevich, T., Mirelman, A., Giladi, N., Orr-Urtreger, A., & Alcalay, R. N. (2025). The effect of polygenic risk score on PD risk and phenotype in LRRK2 G2019S and GBA1 carriers. Journal of Parkinson’s Disease. https://doi.org/10.1177/1877718x241310722
Publication Date
Shani, S., Gana-Weisz, M., Bar-Shira, A., Thaler, A., Gurevich, T., Mirelman, A., Giladi, N., Alcalay, R. N., Orr-Urtreger, A., & Goldstein, O. (2024). P2RX7, an adaptive immune response gene, is associated with Parkinson’s disease risk and age at onset. Journal of Parkinson’s Disease. https://doi.org/10.1177/1877718x241296015
Publication Date
Cook, L., Verbrugge, J., Schwantes-An, T.-H., Schulze, J., Foroud, T., Hall, A., Marder, K. S., Mata, I. F., Mencacci, N. E., Nance, M. A., Schwarzschild, M. A., Simuni, T., Bressman, S., Wills, A.-M., Fernandez, H. H., Litvan, I., Lyons, K. E., Shill, H. A., Singer, C., … Alcalay, R. N. (2024). Parkinson’s disease variant detection and disclosure: PD GENEration, a North American study. Brain, 147(8), 2668–2679. https://doi.org/10.1093/brain/awae142
Publication Date
Fan, Y., Nirujogi, R. S., Garrido, A., Ruiz-Martínez, J., Bergareche-Yarza, A., Mondragón-Rezola, E., Vinagre-Aragón, A., Croitoru, I., Gorostidi Pagola, A., Paternain Markinez, L., Alcalay, R., Hickman, R. A., Düring, J., Gomes, S., Pratuseviciute, N., Padmanabhan, S., Valldeoriola, F., Pérez Sisqués, L., Malagelada, C., … Sammler, E. M. (2021). R1441G but not G2019S mutation enhances LRRK2 mediated Rab10 phosphorylation in human peripheral blood neutrophils. Acta Neuropathologica, 142(3), 475–494. https://doi.org/10.1007/s00401-021-02325-z
Publication Date
Lai, D., Alipanahi, B., Fontanillas, P., Schwantes‐An, T., Aasly, J., Alcalay, R. N., Beecham, G. W., Berg, D., Bressman, S., Brice, A., Brockman, K., Clark, L., Cookson, M., Das, S., Van Deerlin, V., Follett, J., Farrer, M. J., Trinh, J., Gasser, T., … Foroud, T. (2021). Genomewide Association Studies of LRRK2 Modifiers of Parkinson’s Disease. Annals of Neurology, 90(1), 76–88. Portico. https://doi.org/10.1002/ana.26094
Publication Date
Sosero, Y. L., Yu, E., Krohn, L., Rudakou, U., Mufti, K., Ruskey, J. A., Asayesh, F., Laurent, S. B., Spiegelman, D., Fahn, S., Waters, C., Sardi, S. P., Bandres-Ciga, S., Alcalay, R. N., Gan-Or, Z., & Senkevich, K. (2021). LRRK2 p.M1646T is associated with glucocerebrosidase activity and with Parkinson’s disease. Neurobiology of Aging, 103, 142.e1-142.e5. https://doi.org/10.1016/j.neurobiolaging.2021.02.018
Publication Date
Ortega, R. A., Wang, C., Raymond, D., Bryant, N., Scherzer, C. R., Thaler, A., Alcalay, R. N., West, A. B., Mirelman, A., Kuras, Y., Marder, K. S., Giladi, N., Ozelius, L. J., Bressman, S. B., & Saunders-Pullman, R. (2021). Association of Dual LRRK2 G2019S and GBA Variations With Parkinson Disease Progression. JAMA Network Open, 4(4), e215845. https://doi.org/10.1001/jamanetworkopen.2021.5845
Publication Date