Pathophysiology of Lumbar Disc Degeneration and Treatment

Displaying 1 - 47 of 47CSV
Chan, A. K., Upadhyayula, P. S., Tang, A. J., & Chou, D. (2025). Minimally invasive transforaminal lumbar interbody fusion for scoliosis: surgical technique for focal treatment of the lumbosacral fractional curve. Journal of Spine Surgery, 11(1), 125–134. https://doi.org/10.21037/jss-24-127
Publication Date
Cerpa, M., Zuckerman, S. L., Lenke, L. G., Carreon, L. Y., Cheung, K. M. C., Kelly, M. P., Fehlings, M. G., Ames, C. P., Boachie-Adjei, O., Dekutoski, M. B., Kebaish, K. M., Lewis, S. J., Matsuyama, Y., Pellisé, F., Qiu, Y., Schwab, F. J., Smith, J. S., & Shaffrey, C. I. (2025). Long-term follow-up of non‑neurologic and neurologic complications after complex adult spinal deformity surgery: results from the Scoli-RISK-1 study. European Spine Journal. https://doi.org/10.1007/s00586-025-08683-6
Publication Date
Martin, C. T., Yoon, S. T., Alluri, R. K., Benzel, E. C., Bono, C. M., Cho, S. K., Chou, D., Chen, X., Cheung, J. P. Y., Cabrera, J. P., Ćorluka, S., Demetriades, A. K., Gary, M. F., Ghogawala, Z., Hamouda, W., Han, I., Hauri, D., Hsieh, P. C., … Jain, A. (2024). How Reliable is the Assessment of Fusion Status Following ACDF Using Dynamic Flexion-Extension Radiographs? Global Spine Journal. https://doi.org/10.1177/21925682241303107
Publication Date
Christolias, G., Raghunandan, A., Schneider, B. J., Amin, K., Hao, D., & Patel, J. (2024). Factfinders for patient safety: Epidural steroid injection in patients with lumbar spinal stenosis. Interventional Pain Medicine, 3(4), 100444. https://doi.org/10.1016/j.inpm.2024.100444
Publication Date
Holder, E. K., Lee, H., Raghunandan, A., Marshall, B., Michalik, A., Nguyen, M., Saffarian, M., Schneider, B. J., Smith, C. C., Tiegs-Heiden, C. A., Zheng, P., Patel, J., & Levi, D. (2024). FACTFINDERS FOR PATIENT SAFETY: Minimizing risks with cervical epidural injections. Interventional Pain Medicine, 3(3), 100430. https://doi.org/10.1016/j.inpm.2024.100430
Publication Date
Jiang, F., Joshi, H., Badhiwala, J. H., Wilson, J. R. F., Lenke, L. G., Shaffrey, C. I., Cheung, K. M. C., Carreon, L. Y., Dekutoski, M. B., Schwab, F. J., Boachie-Adjei, O., Kebaish, K. M., Ames, C. P., Berven, S. H., Qiu, Y., Matsuyama, Y., Dahl, B. T., Mehdian, H., Pellisé, F., … Fehlings, M. G. (2024). Spinal cord injury in high-risk complex adult spinal deformity surgery: review of incidence and outcomes from the Scoli-RISK-1 study. Spinal Cord Series and Cases, 10(1). https://doi.org/10.1038/s41394-024-00673-y
Publication Date
D’Souza, R. S., Zheng, P., Christolias, G., Holder, E. K., Lee, H., Miller, D. C., Raghunandan, A., Smith, C. C., & Patel, J. (2024). FACTFINDERS for PATIENT SAFETY: Preventing procedure-related complications: Epidural lipomatosis and postpartum steroid exposure. Interventional Pain Medicine, 3(2), 100408. https://doi.org/10.1016/j.inpm.2024.100408
Publication Date
Mathew, J., Zuckerman, S. L., Lin, H., Marciano, G., Simhon, M., Cerpa, M., Lee, N. J., Boddapati, V., Lehman, R. A., Sardar, Z. M., Dyrszka, M. D., Lombardi, J. M., & Lenke, L. G. (2023). Living with a C2-Sacrum Spinal Fusion: Surgical Outcomes and Quality of Life in Patients Fused from C2 to the Sacrum. Global Spine Journal, 14(5), 1542–1551. https://doi.org/10.1177/21925682221149389
Publication Date
Gupta, P., Hassan, F. M., Thomas, G. M., Lombardi, J. M., & Sardar, Z. M. (2022). Influence of Surgeon Specialty on 30-day Outcomes Following Single-Level Cervical Disc Arthroplasty: A Propensity-Matched Analysis. Global Spine Journal, 219256822211394. https://doi.org/10.1177/21925682221139436
Publication Date
Kato, S., Smith, J. S., Driesman, D., Shaffrey, C. I., Lenke, L. G., & Lewis, S. J. (2024). Post-operative bracing following adult spine deformity surgery: Results from the AO Spine surveillance of post-operative management of patients with adult spine deformity. PLOS ONE, 19(4), e0297541. https://doi.org/10.1371/journal.pone.0297541
Publication Date
Diebo, B. G., Alsoof, D., Lafage, R., Daher, M., Balmaceno-Criss, M., Passias, P. G., Ames, C. P., Shaffrey, C. I., Burton, D. C., Deviren, V., Line, B. G., Soroceanu, A., Hamilton, D. K., Klineberg, E. O., Mundis, G. M., Kim, H. J., Gum, J. L., Smith, J. S., Uribe, J. S., … Daniels, A. H. (2024). Impact of Self-Reported Loss of Balance and Gait Disturbance on Outcomes following Adult Spinal Deformity Surgery. Journal of Clinical Medicine, 13(8), 2202. https://doi.org/10.3390/jcm13082202
Publication Date
Kim, D. K., Tang, A. J., Wright, M. A., Rohde, C. H., & Chan, A. K. (2024). 105. Sociodemographic And Hospital-Level Predictors Of Concomitant Muscle Flap Closure After Spinal Fusion Surgeries: A Propensity Score Matched Analysis. Plastic and Reconstructive Surgery - Global Open, 12(S4), 69–70. https://doi.org/10.1097/01.gox.0001015508.91517.fb
Publication Date
Heffernan, M. J., Leonardi, C., Andras, L. M., Fontenot, B., Drake, L., Pahys, J. M., Smith, J. T., Sturm, P. F., Thompson, G. H., Glotzbecker, M. P., Tetreault, T. A., Roye, B. D., & Li, Y. (2024). Lowest instrumented vertebrae in early onset scoliosis: is there a role for a more selective approach? Spine Deformity, 12(4), 1145–1153. https://doi.org/10.1007/s43390-024-00842-x
Publication Date
Zheng, P., Hao, D., Christolias, G., Marshall, B., Smith, C. C., Sudhakaran, S., Patel, J., & McCormick, Z. L. (2024). FactFinders for patient safety: Delaying epidural steroid injections: Infection and safe platelet cutoff. Interventional Pain Medicine, 3(1), 100383. https://doi.org/10.1016/j.inpm.2024.100383
Publication Date
Coury, J. R., Morrissette, C. R., Lee, N. J., Cerpa, M., Sardar, Z. M., Weidenbaum, M., Lehman, R. A., Lombardi, J. M., & Lenke, L. G. (2022). Worse Preoperative Disability is Predictive of Improvement in Disability After Complex Adult Spinal Deformity Surgery. Global Spine Journal, 14(2), 364–369. https://doi.org/10.1177/21925682221104425
Publication Date
Shen, Y., Sardar, Z. M., Malka, M., Katiyar, P., Greisberg, G., Hassan, F., Reyes, J. L., Le Huec, J.-C., Bourret, S., Hasegawa, K., Wong, H. K., Liu, G., Dennis Hey, H. W., Riahi, H., Kelly, M., Lombardi, J. M., & Lenke, L. G. (2024). Characteristics of Spinal Morphology According to the “Current” and “Theoretical” Roussouly Classification Systems in a Diverse, Asymptomatic Cohort: Multi-Ethnic Alignment Normative Study (MEANS). Global Spine Journal. https://doi.org/10.1177/21925682241235611
Publication Date
Mourad, M., Hairston, J. C., Laughlin, A., Louwagie, E., Nhan Chang, C. L., Yan, Q., Reddy, U. M., & Myers, kristin. (2024). 257 Aspirated and computed cervical stiffness throughout gestation for patients with and without a pessary. American Journal of Obstetrics and Gynecology, 230(1), S150–S151. https://doi.org/10.1016/j.ajog.2023.11.279
Publication Date
Byvaltsev, V. A., Kalinin, A. A., Shepelev, V. V., Pestryakov, Y. Y., Biryuchkov, M. Y., Jubaeva, B. A., Boddapati, V., Lehman, R. A., & Riew, K. D. (2022). The Relationship of Radiographic Parameters and Morphological Changes at Various Stages of Degeneration of the Lumbar Facet Joints: Cadaver Study. Global Spine Journal, 14(1), 195–203. https://doi.org/10.1177/21925682221099471
Publication Date
Kenawy, H. M., Nuñez, M. I., Morales, X., Lisiewski, L. E., Burt, K. G., Kim, M. K. M., Campos, L., Kiridly, N., Hung, C. T., & Chahine, N. O. (2023). Sex differences in the biomechanical and biochemical responses of caudal rat intervertebral discs to injury. JOR SPINE, 6(4). Portico. https://doi.org/10.1002/jsp2.1299
Publication Date
Benes, G., Roye, B. D., Stikeleather, L., Hresko, M. T., Sucato, D. J., Welborn, M. C., McClellan, C., & Sponseller, P. D. (2023). Scoliosis Bracing: Details Make the Difference. Journal of the Pediatric Orthopaedic Society of North America, 5(4), 776. https://doi.org/10.55275/jposna-2023-776
Publication Date
Chanbour, H., Tang, A. R., Steinle, A. M., Jonzzon, S., Roth, S. G., Gardocki, R. J., Stephens, B. F., Abtahi, A. M., & Zuckerman, S. L. (2023). In Reply: Transforaminal Lumbar Interbody Fusion Versus Posterolateral Fusion Alone in the Treatment of Grade 1 Degenerative Spondylolisthesis. Neurosurgery, 94(1), e15–e16. https://doi.org/10.1227/neu.0000000000002747
Publication Date
Theologis, A. A., Cummins, D. D., Kato, S., Lewis, S., Shaffrey, C., Lenke, L., & Berven, S. H. (2023). Activity and sports resumption after long segment fusions to the pelvis for adult spinal deformity: survey results of AO Spine members. Spine Deformity, 11(6), 1485–1493. https://doi.org/10.1007/s43390-023-00734-6
Publication Date
Fourman, M. S., Lafage, R., Lovecchio, F., Sheikh Alshabab, B., Shah, S., Punyala, A., Ang, B., Elysee, J., Lenke, L. G., Kim, H. J., Schwab, F., & Lafage, V. (2022). How Does Gravity Influence the Distribution of Lordosis in Patients With Sagittal Malalignment? Global Spine Journal, 13(8), 2446–2453. https://doi.org/10.1177/21925682221087467
Publication Date
Diebo, B. G., Tataryn, Z., Alsoof, D., Lafage, R., Hart, R. A., Passias, P. G., Ames, C. P., Scheer, J. K., Lewis, S. J., Shaffrey, C. I., Burton, D. C., Deviren, V., Line, B. G., Soroceanu, A., Hamilton, D. K., Klineberg, E. O., Mundis, G. M., Kim, H. J., … Gum, J. L. (2023). Height Gain Following Correction of Adult Spinal Deformity. Journal of Bone and Joint Surgery, 105(18), 1410–1419. https://doi.org/10.2106/jbjs.23.00031
Publication Date
Echt, M., Bakare, A. A., Varela, J. R., Platt, A., Abdul Sami, M., Molenda, J., Kerolus, M., & Fessler, R. G. (2023). Comparison of minimally invasive decompression alone versus minimally invasive short-segment fusion in the setting of adult degenerative lumbar scoliosis: a propensity score–matched analysis. Journal of Neurosurgery: Spine, 1–10. https://doi.org/10.3171/2023.4.spine221047
Publication Date
Joaquim, A. F., Martins, C. R., & Riew, K. D. (2022). How Knowledgeable Are Spine Surgeons Regarding EMG-NCS for Cervical Spine Conditions? An International Aospine Survey. Global Spine Journal, 13(7), 2033–2046. https://doi.org/10.1177/21925682211068795
Publication Date
Malka, M., Sardar, Z. M., Czerwonka, N., Coury, J. R., Reyes, J. L., Le Huec, J.-C., Bourret, S., Hasegawa, K., Wong, H.-K., Liu, G., Hey, H. W. D., Riahi, H., Kelly, M., & Lenke, L. G. (2023). The Thoracolumbar Inflection Point in a Population of Asymptomatic Volunteers: A Multi-Ethnic Alignment Normative Study Cohort Study. Global Spine Journal. https://doi.org/10.1177/21925682231193619
Publication Date
Columbia Affiliation
Nguyen, M., Saffarian, M., Smith, C. C., Holder, E. K., Lee, H., Marshall, B. J., Mattie, R., Patel, J., Schneider, B., & McCormick, Z. L. (2023). FactFinders for patient safety: Understanding potential procedure-related complications: RFN/multifidus atrophy, intradiscal biologics, and facet cyst rupture. Interventional Pain Medicine, 2(2), 100248. https://doi.org/10.1016/j.inpm.2023.100248
Publication Date
Hassan, F. M., Lenke, L. G., Berven, S. H., Kelly, M. P., Smith, J. S., Shaffrey, C. I., Dahl, B. T., de Kleuver, M., Spruit, M., Pellise, F., Cheung, K. M. C., Alanay, A., Polly, D. W., Sembrano, J., Matsuyama, Y., Qiu, Y., & Lewis, S. J. (2023). Independent Prognostic Factors Associated With Improved Patient-Reported Outcomes in the Prospective Evaluation of Elderly Deformity Surgery (PEEDS) Study. Global Spine Journal, 219256822311741. https://doi.org/10.1177/21925682231174182
Publication Date
Zuckerman, S. L., Chanbour, H., Hassan, F. M., Lai, C. S., Shen, Y., Kerolus, M. G., Ha, A., Buchanan, I., Lee, N. J., Leung, E., Cerpa, M., Lehman, R. A., & Lenke, L. G. (2023). The Lumbosacral Fractional Curve vs Maximum Coronal Cobb Angle in Adult Spinal Deformity Patients with Coronal Malalignment: Which Matters More? Global Spine Journal, 219256822311615. https://doi.org/10.1177/21925682231161564
Publication Date
Jentzsch, T., Lewis, S. J., Oitment, C., Rienmüller, A., Martin, A. R., Nielsen, C. J., Shear-Yashuv, H., de Kleuver, M., Qiu, Y., Matsuyama, Y., Lenke, L. G., Alanay, A., Pellisé-Urquiza, F., Cheung, K. M. C., Spruit, M., Polly, D. W., Sembrano, J. N., Shaffrey, C. I., … Smith, J. S. (2023). The Influence of Multilevel Spinal Deformity Surgery on the EuroQol 5 Dimensions’ (EQ-5D) Questionnaire and Residential Status in the Elderly: A Prospective, Observational, Multicenter Study. Global Spine Journal, 219256822311625. https://doi.org/10.1177/21925682231162574
Publication Date
Saffarian, M., Christolias, G., Babaria, V., Patel, J., Nguyen, M. C., Smith, C. C., Miller, D. C., & McCormick, Z. L. (2023). FactFinders for patient safety: Motor stimulation testing in lumbar radiofrequency neurotomy and radiofrequency neurotomy in patients with posterior hardware. Interventional Pain Medicine, 2(1), 100170. https://doi.org/10.1016/j.inpm.2022.100170
Publication Date
Smith, J. S., Elias, E., Sursal, T., Line, B., Lafage, V., Lafage, R., Klineberg, E., Kim, H. J., Passias, P., Nasser, Z., Gum, J. L., Eastlack, R., Daniels, A., Mundis, G., Hostin, R., Protopsaltis, T. S., Soroceanu, A., Hamilton, D. K., … Kelly, M. P. (2023). How Good Are Surgeons at Achieving Their Preoperative Goal Sagittal Alignment Following Adult Deformity Surgery? Global Spine Journal, 219256822311613. https://doi.org/10.1177/21925682231161304
Publication Date
Schupper, A. J., Lin, J. D., Osorio, J. A., Lee, N. J., Steinberger, J. M., Lombardi, J. M., Lehman, R. A., & Lenke, L. G. (2022). Freehand Juxtapedicular Screws Placed in the Apical Concavity of Adult Idiopathic Scoliosis Patients: Technique, Computed Tomography Confirmation, and Radiographic Results. Neurospine, 19(4), 1116–1121. https://doi.org/10.14245/ns.2244798.399
Publication Date
Mattie, R., Schneider, B. J., Miller, D. C., Popescu, A., Smith, C. C., & McCormick, Z. L. (2022). Factfinders for patient safety: Antibiotics for disc access and spinal cord stimulation trials. Interventional Pain Medicine, 1(4), 100150. https://doi.org/10.1016/j.inpm.2022.100150
Publication Date
Danford, N. C., Boddapati, V., Simhon, M. E., Lee, N. J., Mathew, J., Lombardi, J. M., Sardar, Z. M., Lenke, L. G., & Lehman, R. A. (2022). Clinical Trial Quality Assessment in Adult Spinal Surgery: What Do Publication Status, Funding Source, and Result Reporting Tell Us? Global Spine Journal, 12(8), 1904–1911. https://doi.org/10.1177/21925682211073313
Publication Date
Good, C. R., Orosz, L. D., Lehman, R. A., Gum, J. L., Fox, D., & Lieberman, I. H. (2022). Minimally Invasive Posterior Facet Decortication and Fusion Using Navigated Robotic Guidance: Feasibility and Workflow Optimization. Neurospine, 19(3), 773–779. https://doi.org/10.14245/ns.2244190.095
Publication Date
Columbia Affiliation
Lee, N. J., Leung, E., Buchanan, I. A., Geiselmann, M., Coury, J. R., Simhon, M. E., Zuckerman, S., Buchholz, A. L., Pollina, J., Jazini, E., Haines, C., Schuler, T. C., Good, C. R., Lombardi, J., & Lehman, R. A. (2022). A multicenter study of the 5-year trends in robot-assisted spine surgery outcomes and complications. Journal of Spine Surgery, 8(1), 9–20. https://doi.org/10.21037/jss-21-102
Publication Date
Jain, D., Kelly, M. P., Gornet, M. F., Kenneth Burkus, J., Hodges, S. D., Dryer, R. F., McConnell, J. R., Lanman, T. H., & Daniel Riew, K. (2022). Impact of Cervical Disc Arthroplasty vs Anterior Cervical Discectomy and Fusion on Driving Disability: Post Hoc Analysis of a Randomized Controlled Trial With 10-Year Follow-Up. International Journal of Spine Surgery, 16(1), 95–101. https://doi.org/10.14444/8199
Publication Date
Smith, C., Miller, D. C., Saffarian, M., & McCormick, Z. L. (2022). FactFinders for patient safety: Antithrombotics and interventional pain procedures -- lumbar transforaminal epidural steroid injections and lumbar medial branch radiofrequency neurotomy. Interventional Pain Medicine, 1(1), 100008. https://doi.org/10.1016/j.inpm.2021.100008
Publication Date
Patel, A. K., Chang, J. L., Haffey, P. R., Mainkar, O., & Gulati, A. (2022). Characterizing an angle of cannula insertion for Lumbar Medial Branch Radiofrequency Neurotomy: A retrospective observational study. Interventional Pain Medicine, 1(1), 100071. https://doi.org/10.1016/j.inpm.2022.100071
Publication Date
Tetreault, L., Garwood, P., Gharooni, A.-A., Touzet, A. Y., Nanna-Lohkamp, L., Martin, A., Wilson, J., Harrop, J. S., Guest, J., Kwon, B. K., Milligan, J., Arizala, A. M., Riew, K. D., Fehlings, M. G., Kotter, M. R. N., Kalsi-Ryan, S., & Davies, B. M. (2021). Improving Assessment of Disease Severity and Strategies for Monitoring Progression in Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 4]. Global Spine Journal, 12(1_suppl), 64S-77S. https://doi.org/10.1177/21925682211063854
Publication Date
Hilton, B., Gardner, E. L., Jiang, Z., Tetreault, L., Wilson, J. R. F., Zipser, C. M., Riew, K. D., Guest, J. D., Harrop, J. S., Fehlings, M. G., Rodrigues-Pinto, R., Rahimi-Movaghar, V., Aarabi, B., Koljonen, P. A., Kotter, M. R. N., Davies, B. M., & Kwon, B. K. (2022). Establishing Diagnostic Criteria for Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 3]. Global Spine Journal, 12(1_suppl), 55S-63S. https://doi.org/10.1177/21925682211030871
Publication Date
Khan, A., Soliman, M. A. R., Lee, N. J., Waqas, M., Lombardi, J. M., Boddapati, V., Levy, L. C., Mao, J. Z., Park, P. J., Mathew, J., Lehman, R. A., Mullin, J. P., & Pollina, J. (2022). CT-to-fluoroscopy registration versus scan-and-plan registration for robot-assisted insertion of lumbar pedicle screws. Neurosurgical Focus, 52(1), E8. https://doi.org/10.3171/2021.10.focus21506
Publication Date
Wolf, C., Betz, U., Huthwelker, J., Konradi, J., Westphal, R. S., Cerpa, M., Lenke, L., & Drees, P. (2021). Evaluation of 3D vertebral and pelvic position by surface topography in asymptomatic females: presentation of normative reference data. Journal of Orthopaedic Surgery and Research, 16(1). https://doi.org/10.1186/s13018-021-02843-2
Publication Date